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101 Cards in this Set
- Front
- Back
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3 types diseases CAUSED BY FUNGI
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1) Allergic: Hypersensitivity to fungal propagules
2) Mycotoxicoses: accidental or recreational ingestion of toxic fungal metabolites 3) Infection |
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FUNGAL ALLERGIES ARE USUALLY TYPE
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1-IGE MEDIATED
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D MUSHROOM POSINING
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MUSHROOM PROUDCE LOTS OF TOXINS. MOST COMMON ARE GASTROINTESTINAL IRRITANTS.
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D AMANTININ MUSCHROOM TOXIN
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MUSHROOM TOXIN
Amanitin: cyclic polypeptide RNA inhibitors, liver failure. Extremely lethal (50% mortality). Effects are delayed 6-24h, toxin absorption must be prevented VERY DANGEROUS TOXIN! |
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D MUSCARINE MUSHROOM TOXIN
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FOCUS ON ANS
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D ISOXAZOLE DERIVATIVES MUSHOROOM TOXIN
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CAUSE CNS EFFECTS. RECOVERY SPONTANEOUS.
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D GYROMITRIN MUSHROOM TOXIN
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NUEROTOXIN, GI TRACT TOXIN, HEMATOPPOITIC TOXIN. RARE
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D ERGOT ALCOILOIDS
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COMMONLY GROW ON WHEAT BARLEY RYE. INJESTION OF EFTOGT RESULTS IN ERGATISM: A VARIETY OF SX LIKE GANGRENE, ODD BEHAVIOR.
CONTRIBUTED TO SALEM WHICH TRIALS? PEOPLE WHO INJESTED ALCOLOIDS STRATED ACTED STANGE. USE CROP DUSTERS TO PREVENT GROWTH ON GRAINS. |
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D ALFOTOXINS
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GROWS ON CORN COTTONSEED, PENUTS
CARCINOGENIC-POTENT TARGETS LIVER-CANCER AND FAILURE |
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D FUMONISINS
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INVOLVED IN CANCER
INHIBITS CEREMAIDE SYNTHSASE FROM AGRUCULTURAL PRODUCTS |
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D OCHRATOXIN
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- Produced by Aspergillus and Penicillium sp
- Nephrotoxic, teratogenic, and carcinogenic in animal models - Linked to nephritis in humans |
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TYPES FUNGAL INFECTIONS
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SUPERFICIAL-TINEA
CUTANEOUS-RINGWORN ENDEMIC-DIMORPHICS, MORE VIRULENT OPPORTUNISTIC-IN IMMUNE COMPRIMISED |
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D OCHRATOXIN
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- Produced by Aspergillus and Penicillium sp
- Nephrotoxic, teratogenic, and carcinogenic in animal models - Linked to nephritis in humans |
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WHAT TYPES OF TISSUE DO FUNGI COLONIZE
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- Superficial Mycoses: outer layers of skin and hair
- Cutaneous Mycoses: epidermis, nails, hair cortex - Subcutaneous Mycoses: dermis, subcutis, fascia, bone - Systemic/Endemic Mycoses: inhalation and dissemination |
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D SUPERFICIAL MYCOSES
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LIMITED TO OUTERMOST LAYER OF STRATUM CORNERUM OR TO THE CUTICLE OF HAIR SHAFT.
NO DISCUMFORT. RESPOND WELL TO TREATMENT. |
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D OCHRATOXIN
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- Produced by Aspergillus and Penicillium sp
- Nephrotoxic, teratogenic, and carcinogenic in animal models - Linked to nephritis in humans |
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TX SUPERFICIAL MYCOSES
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TOPICAL TX
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TYPES FUNGAL INFECTIONS
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SUPERFICIAL-TINEA
CUTANEOUS-RINGWORN ENDEMIC-DIMORPHICS, MORE VIRULENT OPPORTUNISTIC-IN IMMUNE COMPRIMISED |
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4 MAJOR SUPERIFICAL MYCOSES
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A. Tinea versicolor/Seborrheic dermatitis (Malasezzia furfur)
B. Tinea nigra (Exophiala werneckii) C. Black piedra (Piedraia hortai) D. White piedra (Trichosporon beigeleii) |
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TYPES FUNGAL INFECTIONS
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SUPERFICIAL-TINEA
CUTANEOUS-RINGWORN ENDEMIC-DIMORPHICS, MORE VIRULENT OPPORTUNISTIC-IN IMMUNE COMPRIMISED |
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D OCHRATOXIN
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- Produced by Aspergillus and Penicillium sp
- Nephrotoxic, teratogenic, and carcinogenic in animal models - Linked to nephritis in humans |
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WHAT TYPES OF TISSUE DO FUNGI COLONIZE
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- Superficial Mycoses: outer layers of skin and hair
- Cutaneous Mycoses: epidermis, nails, hair cortex - Subcutaneous Mycoses: dermis, subcutis, fascia, bone - Systemic/Endemic Mycoses: inhalation and dissemination |
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D TINEA VERISCOLOR. WHERE DOES IT INFECT? APPEARANCE?
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LIPOPHILIC FUNGUS. COLONIZES SEBACEOUS GLAND REGIONS.
SPAGHETTI AND MEATBALL APPEARANCE. |
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TYPES FUNGAL INFECTIONS
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SUPERFICIAL-TINEA
CUTANEOUS-RINGWORN ENDEMIC-DIMORPHICS, MORE VIRULENT OPPORTUNISTIC-IN IMMUNE COMPRIMISED |
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D SUPERFICIAL MYCOSES
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LIMITED TO OUTERMOST LAYER OF STRATUM CORNERUM OR TO THE CUTICLE OF HAIR SHAFT.
NO DISCUMFORT. RESPOND WELL TO TREATMENT. |
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WHAT TYPES OF TISSUE DO FUNGI COLONIZE
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- Superficial Mycoses: outer layers of skin and hair
- Cutaneous Mycoses: epidermis, nails, hair cortex - Subcutaneous Mycoses: dermis, subcutis, fascia, bone - Systemic/Endemic Mycoses: inhalation and dissemination |
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WHAT ARE 2 CUTANEOUS FUNAL INFECTION
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RINGWORM AND TINEAS
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D OCHRATOXIN
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- Produced by Aspergillus and Penicillium sp
- Nephrotoxic, teratogenic, and carcinogenic in animal models - Linked to nephritis in humans |
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WHAT TYPES OF TISSUE DO FUNGI COLONIZE
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- Superficial Mycoses: outer layers of skin and hair
- Cutaneous Mycoses: epidermis, nails, hair cortex - Subcutaneous Mycoses: dermis, subcutis, fascia, bone - Systemic/Endemic Mycoses: inhalation and dissemination |
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NAME FUNGI THAT CUASE RING WORM
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Infections that are caused by a group of keratinophilic fungi termed dermatophytes
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D SUPERFICIAL MYCOSES
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LIMITED TO OUTERMOST LAYER OF STRATUM CORNERUM OR TO THE CUTICLE OF HAIR SHAFT.
NO DISCUMFORT. RESPOND WELL TO TREATMENT. |
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TX SUPERFICIAL MYCOSES
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TOPICAL TX
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TYPES FUNGAL INFECTIONS
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SUPERFICIAL-TINEA
CUTANEOUS-RINGWORN ENDEMIC-DIMORPHICS, MORE VIRULENT OPPORTUNISTIC-IN IMMUNE COMPRIMISED |
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TX SUPERFICIAL MYCOSES
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TOPICAL TX
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T/F RINGWROM NOT INFECTIOUS BEYOUND KARATIZED SKIN
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T
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WHAT TYPES OF TISSUE DO FUNGI COLONIZE
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- Superficial Mycoses: outer layers of skin and hair
- Cutaneous Mycoses: epidermis, nails, hair cortex - Subcutaneous Mycoses: dermis, subcutis, fascia, bone - Systemic/Endemic Mycoses: inhalation and dissemination |
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4 MAJOR SUPERIFICAL MYCOSES
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A. Tinea versicolor/Seborrheic dermatitis (Malasezzia furfur)
B. Tinea nigra (Exophiala werneckii) C. Black piedra (Piedraia hortai) D. White piedra (Trichosporon beigeleii) |
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D SUPERFICIAL MYCOSES
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LIMITED TO OUTERMOST LAYER OF STRATUM CORNERUM OR TO THE CUTICLE OF HAIR SHAFT.
NO DISCUMFORT. RESPOND WELL TO TREATMENT. |
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4 MAJOR SUPERIFICAL MYCOSES
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A. Tinea versicolor/Seborrheic dermatitis (Malasezzia furfur)
B. Tinea nigra (Exophiala werneckii) C. Black piedra (Piedraia hortai) D. White piedra (Trichosporon beigeleii) |
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D SUPERFICIAL MYCOSES
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LIMITED TO OUTERMOST LAYER OF STRATUM CORNERUM OR TO THE CUTICLE OF HAIR SHAFT.
NO DISCUMFORT. RESPOND WELL TO TREATMENT. |
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D TINEA VERISCOLOR. WHERE DOES IT INFECT? APPEARANCE?
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LIPOPHILIC FUNGUS. COLONIZES SEBACEOUS GLAND REGIONS.
SPAGHETTI AND MEATBALL APPEARANCE. |
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TX SUPERFICIAL MYCOSES
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TOPICAL TX
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TX SUPERFICIAL MYCOSES
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TOPICAL TX
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D TINEA VERISCOLOR. WHERE DOES IT INFECT? APPEARANCE?
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LIPOPHILIC FUNGUS. COLONIZES SEBACEOUS GLAND REGIONS.
SPAGHETTI AND MEATBALL APPEARANCE. |
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4 MAJOR SUPERIFICAL MYCOSES
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A. Tinea versicolor/Seborrheic dermatitis (Malasezzia furfur)
B. Tinea nigra (Exophiala werneckii) C. Black piedra (Piedraia hortai) D. White piedra (Trichosporon beigeleii) |
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D OCHRATOXIN
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- Produced by Aspergillus and Penicillium sp
- Nephrotoxic, teratogenic, and carcinogenic in animal models - Linked to nephritis in humans |
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WHAT ARE 2 CUTANEOUS FUNAL INFECTION
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RINGWORM AND TINEAS
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D OCHRATOXIN
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- Produced by Aspergillus and Penicillium sp
- Nephrotoxic, teratogenic, and carcinogenic in animal models - Linked to nephritis in humans |
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WHAT ARE 2 CUTANEOUS FUNAL INFECTION
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RINGWORM AND TINEAS
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D TINEA VERISCOLOR. WHERE DOES IT INFECT? APPEARANCE?
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LIPOPHILIC FUNGUS. COLONIZES SEBACEOUS GLAND REGIONS.
SPAGHETTI AND MEATBALL APPEARANCE. |
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4 MAJOR SUPERIFICAL MYCOSES
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A. Tinea versicolor/Seborrheic dermatitis (Malasezzia furfur)
B. Tinea nigra (Exophiala werneckii) C. Black piedra (Piedraia hortai) D. White piedra (Trichosporon beigeleii) |
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NAME FUNGI THAT CUASE RING WORM
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Infections that are caused by a group of keratinophilic fungi termed dermatophytes
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TYPES FUNGAL INFECTIONS
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SUPERFICIAL-TINEA
CUTANEOUS-RINGWORN ENDEMIC-DIMORPHICS, MORE VIRULENT OPPORTUNISTIC-IN IMMUNE COMPRIMISED |
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TYPES FUNGAL INFECTIONS
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SUPERFICIAL-TINEA
CUTANEOUS-RINGWORN ENDEMIC-DIMORPHICS, MORE VIRULENT OPPORTUNISTIC-IN IMMUNE COMPRIMISED |
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D TINEA VERISCOLOR. WHERE DOES IT INFECT? APPEARANCE?
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LIPOPHILIC FUNGUS. COLONIZES SEBACEOUS GLAND REGIONS.
SPAGHETTI AND MEATBALL APPEARANCE. |
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WHAT ARE 2 CUTANEOUS FUNAL INFECTION
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RINGWORM AND TINEAS
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T/F RINGWROM NOT INFECTIOUS BEYOUND KARATIZED SKIN
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T
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WHAT TYPES OF TISSUE DO FUNGI COLONIZE
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- Superficial Mycoses: outer layers of skin and hair
- Cutaneous Mycoses: epidermis, nails, hair cortex - Subcutaneous Mycoses: dermis, subcutis, fascia, bone - Systemic/Endemic Mycoses: inhalation and dissemination |
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NAME FUNGI THAT CUASE RING WORM
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Infections that are caused by a group of keratinophilic fungi termed dermatophytes
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WHAT TYPES OF TISSUE DO FUNGI COLONIZE
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- Superficial Mycoses: outer layers of skin and hair
- Cutaneous Mycoses: epidermis, nails, hair cortex - Subcutaneous Mycoses: dermis, subcutis, fascia, bone - Systemic/Endemic Mycoses: inhalation and dissemination |
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T/F RINGWROM NOT INFECTIOUS BEYOUND KARATIZED SKIN
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T
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NAME FUNGI THAT CUASE RING WORM
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Infections that are caused by a group of keratinophilic fungi termed dermatophytes
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D SUPERFICIAL MYCOSES
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LIMITED TO OUTERMOST LAYER OF STRATUM CORNERUM OR TO THE CUTICLE OF HAIR SHAFT.
NO DISCUMFORT. RESPOND WELL TO TREATMENT. |
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WHAT ARE 2 CUTANEOUS FUNAL INFECTION
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RINGWORM AND TINEAS
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D SUPERFICIAL MYCOSES
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LIMITED TO OUTERMOST LAYER OF STRATUM CORNERUM OR TO THE CUTICLE OF HAIR SHAFT.
NO DISCUMFORT. RESPOND WELL TO TREATMENT. |
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T/F RINGWROM NOT INFECTIOUS BEYOUND KARATIZED SKIN
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T
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NAME FUNGI THAT CUASE RING WORM
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Infections that are caused by a group of keratinophilic fungi termed dermatophytes
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TX SUPERFICIAL MYCOSES
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TOPICAL TX
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TX SUPERFICIAL MYCOSES
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TOPICAL TX
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4 MAJOR SUPERIFICAL MYCOSES
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A. Tinea versicolor/Seborrheic dermatitis (Malasezzia furfur)
B. Tinea nigra (Exophiala werneckii) C. Black piedra (Piedraia hortai) D. White piedra (Trichosporon beigeleii) |
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T/F RINGWROM NOT INFECTIOUS BEYOUND KARATIZED SKIN
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T
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D TINEA VERISCOLOR. WHERE DOES IT INFECT? APPEARANCE?
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LIPOPHILIC FUNGUS. COLONIZES SEBACEOUS GLAND REGIONS.
SPAGHETTI AND MEATBALL APPEARANCE. |
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4 MAJOR SUPERIFICAL MYCOSES
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A. Tinea versicolor/Seborrheic dermatitis (Malasezzia furfur)
B. Tinea nigra (Exophiala werneckii) C. Black piedra (Piedraia hortai) D. White piedra (Trichosporon beigeleii) |
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WHAT ARE 2 CUTANEOUS FUNAL INFECTION
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RINGWORM AND TINEAS
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D TINEA VERISCOLOR. WHERE DOES IT INFECT? APPEARANCE?
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LIPOPHILIC FUNGUS. COLONIZES SEBACEOUS GLAND REGIONS.
SPAGHETTI AND MEATBALL APPEARANCE. |
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WHAT ARE 2 CUTANEOUS FUNAL INFECTION
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RINGWORM AND TINEAS
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NAME FUNGI THAT CUASE RING WORM
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Infections that are caused by a group of keratinophilic fungi termed dermatophytes
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T/F RINGWROM NOT INFECTIOUS BEYOUND KARATIZED SKIN
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T
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NAME FUNGI THAT CUASE RING WORM
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Infections that are caused by a group of keratinophilic fungi termed dermatophytes
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T/F RINGWROM NOT INFECTIOUS BEYOUND KARATIZED SKIN
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T
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WHAT ARE 4 TYPES OF DERMATOPHYTES BASED ON LOCATION
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A. Skin
B. Ectothrix C. Endothrix D. Favic |
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D: Ectothrix Infection:
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Spores surrounding the hair shaft
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DX ECTOTHRIX INFECTION
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Infected hairs often fluoresce under Wood's lamp
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D ENDOTHRIX INFEXION
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INVASIVE FUNAL ELEMENTS INSIDE HAIR SHAFT
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D FAVIC INFECTION
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T. schoenlenii, infection of the
base of the hair shaft. Hyphal elements course throughout hair- alopecia is common |
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TINEA PEDIS CAUSES
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ATHLETE'S FOOT
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TINEA BARBA
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BEARD RING WORM
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D SUBCUTANEOUS MYCOSES
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Wide spectrum of infections caused by a
heterogeneous group of fungi. Involves the deeper layers of the dermis, subcutaneous tissue, and epidermis. |
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ROUTE OF ENTRY SUBCUTANEOUS MYCOSES
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MECHANICAL TRAMUA. LESIONS GENREAL OCCUR AT SITE OF TRAUMA
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HOW DO SUBCUTANEOUS MYCOSES SPREAD IN BODY
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VIA LYMPHATICS
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D SPOROTRICHOSIS
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DIORPHIC FUNGUS. YEAST ISOLATED FROM INFECTION. UBIQUTOUS SOURCE.
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MOST COMMON SPOROTRICHOSIS
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LYMPHOCUTANEOUS SPOROTICHOSIS
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D SPOROTRICHOSIS LESIONS
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Lesion starts as hard, painless mass, may become fluctuant and
eventually ulcerate |
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SPOROTROCHOSIS INFECTION SPREADS VIA
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LYMPHATICS
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SPOROTROCHOSIS CAN HAVE BONE AND PULMONARY MANIFSETATION.T/F
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T
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SPOROTRICHOSIS FORM -------- AT BODY TEMP
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YEASTS
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SUBCUTANEOUS MICOSES
D Chromoblastomycosis |
infections caused by dematiaceous (pigmented) fungi
NODULES AT INNOCULATION SITE, ITCHY, PROGRESSIVE SCLEORTIC BODIES MOST COMMON IN TROPICS SURGERY MAY BE NEEDED SPREAD VIA LYMPHATICS |
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CHROMBOBLASTOMYCOSIS Etiologic agents include:
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Cladosporium carrionii, Fonsecaea pedrosoi, F. compacta, Phialophora verrucosa, Rhinocladiella spp., Exophiala spp.
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Subcutaneous Mycoses:
D Eumycotic Mycetoma |
NON PIGMENTED FUNGI
STARTS AROUND FOOT AND MAKES TUMOR THAT GETS BIG LOCALLY RATHER THAN SPREAD LYMPHATICALLY CHORNIC DISEASE FORMS CHARACTERISTIC "GRAINS" IN DRAINING SINUSES TX IS DIFFICULT USUALLY WITH SURGERY AND AZOLE THERAPY COMBO |
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D GRAINS
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SULFUR GRANULES CHARACTERISTIC OF EUMYCOTIC MYCETOMA
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2 SUBCUNTANOUS MYCOSES ARE
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Eumycotic Mycetoma
D Chromoblastomycosis |
