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7 Cards in this Set
- Front
- Back
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Explain the concept of Respiratory Control Loop.
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SENSORS (chemoreceptors, lung and other receptors) --> input to the CENTRAL CONTROLLER (pons, medulla, other parts of brain) --> output to EFFECTORS (respiratory muscles) --> SENSORS (repeat)
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What are the three main concepts for the control of ventilation?
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1. Central pattern generation
2. Peripheral chemoreceptors 3. Central chemoreceptors |
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Where is basic rhythm generation generated?
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Medulla oblongata
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Why are peripheral chemoreceptor important?
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They are the only significant source of hypoxic ventilatory drive
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Where are central chemoreceptive regions located?
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Ventro-lateral medulla
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What is the stimulus of central chemoreceptors?
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Fall in pH of cerebrospinal fluid (CSF)
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What are the mechanisms behind CSF?
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Very sensitive to changes in PCO2 and therefore CSF pH is largely dictated by respiratory activity
Little protein therefore limited buffering capacity ie no proteins to mop up excess H ions |
