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54 Cards in this Set

  • Front
  • Back
NEMATODES ARE
ROUNDWORMS
T/F THRE ARE MALE AND FEMALE NEMATODES
t
2 types NEMATODES ARE
INTESTINAL AND TISSUE NEMATODES
D INTESTINAL NEMATODDS. DO THEY HAVE TISSUE PHASE?
Presence of the adult nematode in the intestine is responsible for the disease manifestations

No tissue phase - no migration (mouth to intestine)
Minor tissue phase - migration through lung tissue

Closely related animal parasites behave primarily as tissue parasites in humans
D TISSUE NEMATODES
Migration of larval form throughout the host tissue is responsible for the disease manifestations
Trichinella has a minor intestinal phase
WHAT NEAMTODES ARE AQUIRED THROUGH INJESTION
Enterobius vermicularis - pinworm
Trichuris trichiura - whipworm
Ascaris lumbricoides - roundworm
WHICH ARE AQUIRED THORUGH SKIN
Ancylostoma duodenale - hookworm
Necator americanus - hookworm
Strongyloides stercoralis - threadworm
ENTERBORIS INFECTION MANIFISTATION
Clinical manifestations
Pruritis ani
Irritability, insomnia, bed wetting
Secondary rash and infection
Vaginal discharge
Appendicitis
ENTEROBIUS VERMICULARIS=
PINWORM (RUSSIAN=GLIST?)
ENTEROBIUS VERMICULARIS CYCLE
FEMALE LAYS EGGS IN ANUS. ANUS ITCHES. ANUS GETS SCATCHED. IF FINGER PLACED IN MOUTH, INFECTION IS INTENSIFIED.
TX ENTEROBIUS VEMICULARIS (PINWORM)
PARANTHOL-OVER THE COUNTER

MEBENDAZOLE

CURE RATE HIGH
T/F PINWORMS ARE COMMON IN SCHOOLS/GENERAL POP
T
Trichuris trichiura =
WHIPWORM
Trichuris trichiura (WHIPWORM) ADULTS LIVE IN
Adults live in cecum where the female worm produces 20,000 eggs per day which are shed with the feces
Trichuris trichiura (WHIPWORM) INFECTION BY
INGESTION OF EGGS
Trichuris trichiura (WHIPWORM) Embryonation IS IN
SOIL
INFECTION SEVERITY WHIPWORM
Infections with less than 10 worms are asymptomatic

Moderate to heavy infections cause abdominal pain, diarrhea, weight loss

Heavily infected children may have profuse bloody diarrhea, cramps, tenesmus and urgency which may result in rectal prolapse
WHIPWORM CAN CAUSE
RECTAL PROLAPSE
DX WHIPWORM
Diagnosis by demonstration of characteristic eggs (“champagne corks”)
TX WHIPWORM
Treatment with mebendazole
Ascaris lumbricoides=
ROUNDWORM
T/F ROUNDWORMS ARE VERY BIG
T
A. SUUM ROUNDWORM INFECTS
PIGS
A. LUMBRCOIDES SPECIES INFECTS
HUMANS
ROUNDWORM MORPHOLOY
BIG, 3 LIP WORM
TRANSMISSION ROUNDWORM
Feces must be deposited on soil

3 weeks to embryonate (become infected)

Eggs accidentally ingested with soil, fruits, vegetables grown close to the ground
ROUNDOWM CYCLE
Fully embryonated eggs are swallowed

Larvae release in the stomach

penetrate stomach or duodenal mucosa wall

Larvae enter blood stream lung

Larvae mature in the lungs move up and get swallowed

Adults live in intestine

Held in jejunum by muscular activity
Live 6 months-2 years
2-3 months eggs produced
ROUNDWORMS HAVE MALES AND FEMALES. T/F
T
T/F UNMATED ROUNDOWRM FEMALE WILL TILL RELEASE UNFERTILIZED EGGS. WHAT IS THE PROBLEM?
T-SHE WILL SEARCH FOR MALE AND MOVE TO OTHER PARTS OF BODY
T/F ROUNDWORM EGGS ARE SENSTIVE TO SUN, BUT OTHERWISE VERY RESISTANT
T
PRESENTATION ROUNDWORM
-INTESTINAL OBSTRUCTION WITH WORNS

-MALNURISHMENT IN CHILDREN

-PULMONARY SX

-PENETRATION OF ORGANS

-DHIARREA

-VOMITING
D VOLVULUS
MASS OF KNOTTED WORMS
TX ROUNDWORM
PIPERAZINE-TASTES REALLY BAD
MEBENDAZOLE
ANCYLOSTOMA DUODENALE AND NECATOR AMERICANUS=
HUMAN HOOKWORMS
LIFE CYCLE HOOKWORMS
Adult worms live in the small intestine
female lay 5-10000 eggs a day over 5 years
Eggs are passed with the feces
Larvae develop outside the human body in soil
The larvae move to the surface in search for a host
If they come into contact with the host they penetrate the skin, enter blood vessels and leave the circulatory system into the alveoli
The larvae move up the trachea are swallowed and finally reach the intestine, reach maturity
GROUND ITCH IS INDICATIVE OF
HOOKWORMS
SX PULMONARY PHASE, FEVER
USUALLY ASSYMPTOMATIC

COUGHING, WHEEZING
INTESTINAL WORMS ATTACH TO----- AND FEED ON----
MUCOSA...BLOOD
HOOKWORMS RESULT IN
ANEMIA
IRON DEFICIENCY
STUNTED GROWTH
FATIQUE
TX HOOKWORMS
mebendazole
STRONGYLOIDIASIS STERCORALIS=
THREADWORM
LIFE CYCLE THREADWORM
Females fertilized by male/parthenogenesis possible

Females burrow into jejunal wall - lays eggs

Eggs hatch release larvae

Larvae enter lumen - pass in feces
THREADWORM INFECTION IS LOCATED IN
ENTIRE BOWEL

BILIEARY AND PANCREATIC DUCT INVOLVED
3 LIFE CYCLE OF THREADOWRM
FREE LIVING
AUTOINFECTION
PENETRATION OF HOST
D FREE LIVING LIFE CYCLE
LIFE OUTSIDE
D PENETRATION LIFE CYCLE
PENETRATE SKIN LIKE HOOKWORM
WHY ARE threadworms DANGEROUS?
NOT VERY VISSIBLE
MISDIAGNOSIS
DEADLY IF DISSEMINATED
threadworm TRANSMISSION
BARE SKIN CONTACT WITH CONTAMINATED SOIL

INJESTION OF FOOD OR MILK

PHYSICAL CONTACT

AUTOINFECTION
threadworm MANIFESTATIONS
Skin
Initial penetration asymptomatic
Red raised serpiginous lesions may develop
Recur at irregular intervals
Common over lower back and buttocks
Probably related to episodes of autoinfections

Pulmonary
coughing, wheezing, and fever
Similar to ascarisis and hookworm disease

Intestinal
Usually asymptomatic small # of worms
Abdominal pain and tenderness (“peptic ulcer)
Flatulance, nausea, vomiting, diarrhea
Malabsorption with weight loss
Ileus with intestinal obstruction-Inhibition of bowel motility
Ulcerative colitis, intestinal perforation
threadworm DISSEMINATION CAUSES
ENCEPHALITIS

HEMORRHAGIC PNEMONIA

DEATH
DX threadworm
DIFFICULT

-FIND LARVAE IN STOOL
-EOSINOPHILIA
-SEROLOGY
TX threadworm
ALBENDAZOLE
IVERMECTIN

TREAT PTS PRIOR TO IMMUNSUPRESSION
PROGNOSIS HOOKWORMS
POOR IN HYPERINFECTIONS
pinworm=
whipworm=
roundworm=
hookworm=
threadworm=
Enterobius vermicularis - pinworm
Trichuris trichiura - whipworm
Ascaris lumbricoides - roundworm
Necator americanus - hookworm
Strongyloides stercoralis - threadworm