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228 Cards in this Set

  • Front
  • Back
Any person, animal, arthpod, plant, soil, substances or combination of; in which an infectious agent normally lives, multiples, or which depends on primarily for survival and where it reproduces itself
Reservior
What are the three modes of Transmission?
a. direct, communicable, indirect
b. Airborne, direct, indirect
c. direct only
d All of the above
b.
What is the definition of Susceptible?
Having little resistance (immunity) to a disease or foreign protein
Infectious disease occuring suddenly in numbers clearly in excess of normal expectancy?
a. host
b. epidemic
c. outbreak
d. Endemic
Epidemic
The period of development of an infecious disease from inoculation to the onset of clinical symptoms?
a. incubation
b. Host
c. Causative agent
d. endemic
Incubation
The initial onsetof infectious disease in a particular host population?
a. host
b. incubation
c. outbreak
d. endemic
outbreak
A specific infectious disease that is present or usually present in a population or geographical area at all times?
a. outbreak
b.endemic
c. incubation
d. epidemic
b. endemic
What are the five sections of the Medic CD rom?
a. Envi., infectious, FHP, Medical, Security
b. Envi. Infectious, FHP, MEdical, Disease
c. FHP, Disease, Enviro., Medical, PHA
b.
What are the parts of Enviornmental Health?
a. key judgementys
b. Hazardoius plants/animals
c. Envir. contamination
d. all the above
d. + physical envirnmental overview, listing information, such as climate, temp.
What 3 things is covered under the INfection disease section of Medic CD?
1. Key judgments
2. Supplents to risk
3. Disease of potential risk
FHP provides a summary of preventive practices to prevent the spread of disease including the following?
major infectious disease countermeasure focus
FHP prior to deployment
FHP during deployment
FHP after deployment
FHP prevmed guide
Provides a list of vector relatied disease as well as recommendiations for vector control on a selected country?
Disease vector profiles
What 5 medical capabiliites are there that provides synopsis of the selected countries ability to furnish medical services and suppor tto operational forces?
Civilian and Military capabiliites
Disaster and emergency response
Social factors
Medical treatment and evacuation facilities
What disease is caused by the orthomyxoviurs, has incubation period of 1-4days with PE findings of Non productive cough, sore throat, constitutional signs and effect mainly young and elderly?
Influenza
What is the definition of influezna?
Acute viral upper respiratory infection caused by influenza type A, B, C
What are the main constitutional symptoms for viral illness?
Fever
Chills
Myalgia
Prostartion
Anorexia
What is rare but severe complication when aspirin is used on children suffering from an influeza/ viral infection?
a. Joe syndrome
b. Triad syndrome
c. Reyes syndrome
d. cushing syndrome
c.
What is the disposition of pt with influenza?
a. bed rest 24-48 hrs or until afebrile
b. RE-check status QD
c. Prognoisi: Duration of uncomplicated cases last from 1-7 days with an excellent .
Acute systemic paramyxocial infection affecting the skin?
Rubeloa (measles)
What is the etiology of Rubeloa?
Transmitted by the infected droplets, which infected the respiratory epithelium and tehn dissemintates to the skin and other organs via monocytes.
What are some Physical findings of r Rubeloa (measles)?
Incubation 10-14 days
prodrome phase begins 2-4days after infection (fever, malaise, Photophobia
***enathem (koplik's spots)
Prodrome phase begins 2-4 days after infection and presents with what signs?
fever
Classic triad: brassy cough, coryza and conjunctivits
Enanthem)koplike spots) white 1-2mm papules appearing on teh buccal mucosa.
Exanthem phase occurs when and shows what type of symptoms?
4 days
Increasing fever peaks 105 degrees and will decline over 24 hrs.
Rash lasts 3-7 day leaving a copper brown crust that desquamtes
Progresses in down and out pattern starting as pin size and brick red, irregular , blocthy and maculopapular, affecting the entire body including the hands and feet
What are some treatments for Rubeloa (measles?
Isoloation
Vit A 200,000 units daily x 2days
Supportive care
Antibiotics for secondary bacteria infections
What are some complications of Rubeloa?
a. splenomegaly endocarditis, COPD
b. Encephalitis, SSPE, Immunocomprised pts/
c. epidymitis, ochitis, vaginitis
d. death, coma, hemorrhagic fever
b.
What is the dispostion of Rubeloa (measles)?
Bed rest for duration of fever
REcheck pt status Q4-6hrs, PRN
Confirm with MO for MEDEVAC
25y/o female in first trimester of pregnancy, with constitiutional symptoms, Conjuncitivits, Lymphadenopathy and rash that develop 4 days after with Palatal macules with exanthema?
Rubella (german)
What is the incubation period of Rubella (german measles)?
14-21 days
What causes Rubella (german measles)?
mild systemic diseas caused by TOGAVIRUS
What are some complications of Geman measles (rubella)?
a. deafness
b. catracts
c. Retinopathy
d. Intrauterine growth retardation
e. Encephalitis
f. all the above
they are all apart of the complications
What is the dispostion of German measles?
a. Iso 3-4 days, Contact MO, MER
b. Iso 10 days, MER and contact MO
c. Contact MO, A&I, Iso 3-4 days
d. Contact MO, Iso 5-7 days, MER
a. Iso to bed rest 3-4days, contact MO, MER
What is acute Generalized paramyxoviral disease causing inflammation of the salivary glands?
a. Chickenpox
b. smallpox
c. mumps
d. Rubella
c.
75% of mumps occure in whom?
teenage years
when is mumps more prevealent?
during the spring
What are some physical findings of mumps?
Incub 14-21
Parotid swelling, tenderness and facial edema are the most common
unilateral 25% and edematous
Drinking citrus or acidic foods exacerbates symptoms
What occurs 85% of all mump cases?
Epididymtitis
What is the treatment for pt over 35 yrs of age with mumps?
Cetriaxone 250mg and Doxycycline 100mg
Over 35 Cipro 500mg
What is the overall treatment of mumps?
Universal precautions
Supportive care
Ensure proper nutrition
what complications occurs 30% of the time of pt with mumps?
1. pancreatitis
2. meningitis
3. hepatitis
4. endocarditis
2.
What is the prognosis of Mumps?
a. most pts recover never
b. course for dz rarley last 2wks and pts recover fine
c. All most dies after 14 days of disease
d. Nothing happens after symptoms reside
most pts recover without incidents and course of dz rarely last two weeks
Pt 10-35y/o with fatigue, malaise, fever, pharyngitis, Post cervical adenopathy with prodrome phase lasting several days. Incubation peiord last 1-2months.
Infectious mono
What causes Mono?
a. hemorrhagic fever
b. mumps
c. Epstein Barr virus
d. adnenovirus type II
c. epstein barr virus
transmitted through close contact via salivia "kissing bug"
What is the treatment for Infectious Mono?
a. ASA 2tabs q4-6hrs prn
b. Tylenol 325 2tabs q-4-6hrs PRN
c. Prednisone 60mg PO QD x 3days
d. Motrin 800mg 1tab q-6 hrs
c. prednisone 60mg x 3days then taper over 1 wk
How long should pts with Mono avoid contact sports and how long is their salvia infectious for?
a. 2 months and 12monts
b. 1 month and 6 mnths
c. 12 months and 6 months
d. 1 month and 1 month
1st month no contact
6 months of infeted saliva
This dz affects ages from 5-10y/o, peaks in springtime and is common and highly contagious viral illness charac. by vesicular rash and fever. The incubation is 10-20 days?
Varicella (chickenpox)
How do the lesions present on pts with varicella (chickenpox?
prominetly on face, scalp and truck progressing to ext.
lesion 2-4 mm red papules with irregular border with a central clear vesicale
"DEW DROPS ON A ROSE PETAL)
New lesion of varicella development generally ceases when and crusts when?
cease on 4th day and crusting by the 6th day
What lab should you do for varicella if diagnosis is in question?
Tzanck smear
What are some treatments for Varicella (chickenpox)?
supportive
diphenhydramine 25mg PO
Calamine lotion
Acyclovir 800mg QID, give within the first 24hrs of prodromal symptoms
What are some complication of Varicella (AIRS)?
ARDS
Ischemic strokes
Reyes syndome
Secondary bacterial infections
Pt comes in with 104temp, BAckache with centrigugal pattern rash starts as flat red lesions, evolving at same rate that are firm, domed or umbilicated. The rash is prominent fo face, arms and legs?
Smallpox
What is the definition of Varioloa (smallpox)?
DNA virus due to the variola virus. It is human virus with no known nonhuman reseviors
When is smallpox most contagious?
a. 3 wk of infection
b. 1 wk of infection
c. all times of infection
d. 4 wk of infection
during the 1st wk of infection
what is the incubation period of smallpox?
a. 1-10 days
b. 5-7 days
c. 7-19 days
d. 28 days
c.
What are some complications for Smallpox?
a. Blepharits, 2nd Bact infection, PNA, dehydration
b. conjuncivitis, hydration, TensionPNA, virual infection
c. Heart attack, corneal ulcers, PNA, stroke
a.
Who do you contact immediately with cases of Smallpox?
a. Prevemed and MO
b. EPMU and infectious dz Physician
c. ER and CDC
d. Public health and CD
b.
What is the mortality rate of Variola major?
a. 10-20%
b. 30-40%
c. 20-50%
d. 80-90%
20-50%
What is group of infectious disease caused by arthropod borne viruses?
Viral hemorrhagic fever
What are the five main genus of viruses?
Arenavirdae
Bunyaviridiae
Filoviridae
Flaviviridae
Paramyxoviridae
90% of this disease is part of the Filoviridae genus?
ebola
What genus does the Hanta virus falls under?
a. Flavivirdiae
b. Paramyxoviridae
c. Arenaviridae
d. Bunyaviridae
d.
What would you find in lates stages of Viral hemorrhagic fever?
Leukopenia
AMS
Hemorrhagic diathesis
What are some treatments of pt's with Viral hemorrhagic fever?
a. supportive and tylenol
b. supportive and Zantac
c. supportive and Tums
d. supporitve and antibiotics
b. Zantac at 150mg bid for GI bleeding
What is the mortality rate of VHF?
a. 5%
b. 15-20%
c. 20%
d. 20-30%
b.
Is usually nonspecific, self limting, febrile illnesss with an incubation period of 7-10day?
Dengue fever
What is the cause of Dengue fever?
a. anopohles
b. blow flow
c. aedes aegypti mosquito
d. sand fly
c.
What are some initial signs of Denque fever?
Constitutional symptoms
Severe myalgia and arthralgias to back
sore thorat
Prostration
Depression
Conjunctival flushing
Redness, flushing, blotching of skin
What is the definition of Dengue fever?
Viral Flaviviurs transmitted by an arthropod bite
What is it meant by biphasic fever curve?
initial fever will last 3-7 days, then a remission period of a few hors to two days followed by another febrile period lasting 1 to 2 days.
Rashes associated with dengue appears 80% of cases and how does the rashes appear?
Scarlatiniform
Morbilliform
Maculopapular
Petechial
Rash can last 2 hrs to several days
Desquamates
What are some treatments for Dengue fever?
Supoortive care
GI bleeding (zantac 150mg BID)
ICe lavage/gavage
Repeat CBC/HCT q 2hrs to tract potential complications. ***expect drop in HCT, with IV hydration
What are some complications of Dengue fever? (BODIP))
Bone marrow failure
Orchitis or oophoritis
Depression
Iritis
PNA
What disease occurs 70--90 % in Bolivia or Peru and has incubation period of 3-6days and affecting 20-40 yrs olds?
Yellow fever
What are the two tramsissable types of yellow fever?
a. sylavitic and blow fly
b. anopheles and dropletic
c. aedes aegyptis and sylvatic (jungle cycle)
c.
What is the toxic phase of Yellow fever?
Jaundice
Oliguria
Albuminuria
Hemorrhage
Encephalopathy
shock
acidosis
What could be some complications of Yellow fever?
Lactic acid build up and shock
myocarditis
Encephalopathy
Decreased synthesis of clotting factors
Disseminated intravascular coagulation
Pt comes in C/O of eye pain, rash fever, chills, myalgia, AMS is flaccid paraylsis, ataxia with Lymphadenopathy lasting 5days. Pt's become infected by the Culex mosquito?
West Nile Virus
What is the definition of West Nile Virus?
a. morbillioform infection
b. encephalitides
c. flavivirus encephalitides
d. none of these
c.
What are some complications of West Nile Virus?
Secondary infections
Urinary retention
Tremors
Seizures
Death
A 25y/o male comes in with bite to the hand, c/o of sore thorat, constitutional symptoms, GI symptoms, pain, on exam you find Extreme hyperactivity, bizarre behaviour, thick tenacious saliva. what is his condition?
rabies
What is the incubation period of rabies?
a. 90 days
b. 10-20days
c. 10-90 days
d. only 20 days
c.
What is the treatment for rabies?
support
Thorough cleaning of wound.
Human rabies immune globulin 20 IU/kg
Anticonvulsant therapy
What are some complications of Rabies?
a. Paralysis and cellulitis
b. Coma, death, paralysis
c. cellulitis and death only
d. no complications can occur
b.
What is the main cause of Poliomyelitis?
a. fecal-oral route by presents of adneovirus
b. fecal-oral route by presents of enterovirus
c. fecal-oral route by presents of staph aerus
d. fecal -oral route by presents of gram postitive bacilli
enterovirus present in throat washings and stool
Transmitted by the fecal oral route
What present of all cases usually results in asymptomacti infection of poliomyelitis?
a. 85%
b. 75%
c. 100%
d. 95%
95%
Those who present with signs of poliomyelitis have one of what three presentations?
a. Paralytic, Nonparalytic, nonabortive
b. abortive, anesthesia, paralytic
c. abortive, nonparalytic, paralytic
d. abortive, paralytic, nonabortive
abortive, nonparalytic and paralytic
What are some signs of Abortive poliomyeylitis?
Constitutional symptoms
Sore throat
diarrhea
constipation
What are some complicatinos of Poliomyelitis?
Urinary retention
UTI
Atelectasis
Myocarditis
PNA
Pul edema
What is the most common cause of hepatitis in the US?
a. Hep B virus
b. Hep C virus
c. Hep A virus
d. Hep E virus
c. HAV
HAV effects whom more?
a. children 1-5y/o
b. children 5-14y/o
c. children 5-10y/o
d. adolescence 10-15y/o
children 5-14
Which hepatitis virus in higher in Europe?
a. HBV
b. HAV
c. HCV
d. HDV
HBV
What is the most common chronic blood borne infection in the US?
a. HDV
b. HEV
c. HBV
d. HCV
HCV accounts for 40% of nonalcoholic liver disease in US
How long does hepatitis last, and when do you expect full recovery?
1. lasting 1-2wks, recover 5-10wks
2. lasing 2-3wks, recover 8-16wks
3. lasing 8-16wks, recover 2-3wks
4. lasting 1wk recovery in 2 wks
disease lasting 2-3 wks and recovery in 8-16 wks
Hepatitis being difficult distinguishing types, what are some prodromal type signs and symptoms of Hepatitis?
Abrupt or insidious onset
constitutional symptoms (varaiable ferver)
Aversion to smoking, distaste
N/V/D or constipation
Stool fatty, floating clay like
ABD pain RUQ
Hepatomegaly over 50-80%
spleomegaly 15%
What would you find in the UA for pt with hepatitis?
a. blood
b. casts
c. bilirubin
d. glycuose
bilirubin
For prognosis which Hep is self limiting, while the others have long term effects?
a. HAV vs HBV/HCV
b. HBV vs. HAV/HDV
c. HCV vs HAV/HBV
d. HGV vs HEV/HBV
Hep A is self limiting as HBV/HCV are chronic and have substantial long term effects
22y/o male reported c/o constitutional symptoms, rigors, conjuntival suffusion, rigors, pharyngitis, lymphadenopathy, splenomeglay. He told you that it started few days ago and that prior he was swimming in a near by river in thailand. What is your diagnosis?
Leptospirosis
What is the definition of Leptospirosis?
Zoonotic disease caused by bacterial spriochete leptospria interrogans
What are some specific labs for Leptospirosis?
CBC, HCT, RPR
UA
Liver panel
24 hr urine
chem10
CHest xray
What is the treatment for Leptospirosis?
a. PCN G and doxycycline
b. Cipro and Doxy
c. Steriods and PCN
d. PCN only
PCN G 6-12 mil units q day IV
Doxycycline 100mg or 200mg if in a endemic area
What is the prognosis of Leptospirosis?
a. excellent
b. self limiting, with admin of Antibiotics less the symptoms
c. even with therapy has morality rate of 10%
d. death
b. self limiting disease but administartion of antibiotics can decrease severity and duration of symptoms
75y/o pt with S/S in last 48hrs with N/V/D, abd cramps, fever. Pt hx of ingesting bad poultry. what is the diagnosis?
Salmonellosis
If Salmonellosis becomes systemic, pts develop with _________ and present with _________?
typhoid fever
presents with increasing malaise, HA, cough, sore thorat abd pain , constipation or diarrhea
Fever 7-10 days..
Pt is suspected to having typhiod fever secondary to Salmonellia, what is the treatment of choice in this case?
a. Doxy 100mg BID x 10days
b. Cipro 500mg PO
c. Ceftriazone 2g PO
d. b & c only.
d.
Treatment of carriers is largely unsuccessful, but recent studies suggest Cipro 500mg PO BID for 4 weeks is highly effective
Relapses occur in what Percent of the cases of salmonilla?
a.10%
b. 20%
c. 15%
d. 30%
15%
Pt comes to the clinic c/o of gray, turbid, withoug fecal odor, blood or pus; describing stool as "rice water stool." No abd pain or fever with mild cramping. He also said he returned from South america a few days ago. what is his DX?
Cholera
What causes cholera?
a. consumption of chicken by chickpox virus
b. consumption of bad water by the vibrio cholera.
c. consumption of shellfish by mecury toxins
d. nonpersistent toxin mediated disease
caused by vibrio cholera, a persistent toxin mediated dz by comsumption of contaminated shellfish and water
What is the first rule of thumb when it comes to treating cholera patients?
a. Antibiotics
b. rest
c. fluid replacment
d. plasma replacement
c.
What is the mixture of contents in water that will help with mild cases of cholera.
a. 1Tsp of salt, 5Tbsp of glucose in 1L H2O
b. 2Tbsp of salt, 5Tbsp of glucose in 1L water
c. 1Tbsp salt, 4 Tbsp of glucsoe in 1L water
c
What antimicrobial therapy will shorten course of diseae of cholera, here are some choices, you figure out which. There are multiple answers
a. Tetracycline
b. PCN
c. Doxy
d. Steriods e. Ampicillin
f. Augmentin g. rocephine
Tetracycline
Doxycycline
Ampicillin
What are some complications of cholera.
a. Hypovolemia, Hypotension, Death
b. Hypervolemia, HTN, Coma
c. Hypercalcemia, Hypocalcemia, Coma
d. Hypokalemia and hypertension
a. Hypovolemia, hypotension, shock and death
What disease has a great potential for use as a bioweapon due to its severe toxicity and durability?
a. E. Coli
b. Yellow fever
c. smallpox
d. botulism
botulism
What is the definition of botulism?
illness resulting from neurotoxin produced by clostridium botulinum.
What is the main causative agent of Botulism?
a. Gram neg bacillus
b. Anaerobic gram-postive Bacillus
c. aerobic gram positive bacillus
d. hemophilic Gram positive bacillus
anaerobic gram-positive bacillus
What are some finding of botulism?
s/s begin 12-36hrs following ingestino
Severity is related to amount
CN palsies (bilateral)
Diploplia
Blurred vision
Ptosis
Dysphagia
Dysarthria
Dry mouth****
N/V/D or constipation and cramps
What are some treatments for botulism?
Antitoxin (trivalent equine botulinum)needs to be given as soon as possible, even prior to lab confirmation.
Give one vial IM, and 1 vial IV
Antitoxin at CDC
Wound botulism PCN 2mil/units IV or Amoxicillin 250mg PO
It is inflammatory disease of the bowel caused by one of several species of shigella?
shigellosis (bacillary dysentery)
What is the most common route of transmission of shigella?
a. indirect only
b. direct only
c. both a and b
d. airborne
c.
Which is the most serious for of shigella?
a. S. sonnei
b. s. aureus
c. S dysenteriae
d. e. coli
c.
What are some physical findings of shigellosis?
incubation 1-3 days
Self limiting
s/s occur abruptly: diarrhea (mixed with blood and mucus
Abd cramping with tenderness
tenesmus
fever
HA, chills, anorexia and malaise
What are some treatments for Shigellosis?
suportive care
Septra DS PO or ciprofloxacin 500mg PO
What are some complications of shigellosis?
Self limiting
dehydration
and severe cases Seizures , intestinal perforatoin and death
This is disease is caused by yersinia pestis and transmitted by the bite of infected flea. Predominately found in China, Laos, Mongolia, India and Vietnam?
Plague
What are some physical findings for pt's with plague?
Incub period is 1-7das
Initial sym. constitutional , sore throat, intense headache, Delirium, Tachycardia
Lymphadentitis, 90% to inguinal nodes
Development of bubo at infection site
If hematogenous spreads for plague, how will the pt present?
a. stupor, petechia spots and paralysis
b. toxic, comatose, purpuric spots (black plague) on skin
c. comatose, malasie, myalgia and spots on hands and feet
d. malasie, myalgia and paralysis with koplike spots
b.
What are some unique lab test for plague?
Gram stain of bubo discharge
Ovoid bipolar gram neg. rod (safety pin appearance

(CBC, RPR, chest films, Serum titer)
How do we treat plauge?
Support
wound cleaning, soap and water
Gentamycin 2mg/kg loading dose, 1.7mg/kg Q8(best choice)
alternative(doxy 100mg)
chloramphenicol 500mg QID IV (ammal prep 1g vials)
What are some complications of Plaque?
a. toxic shock, DIC, Bact Sepsis, fulminant PNA
b. Strep sepsis, Anemia, hypovolemic shock
c. thalassemia, Bact sepsis, StrepPNA
d. folic deficiency, gram neg sepsis, Bronchitis
a
What is the disposition of pt with plague?
Bed rest and strit isolation of pt quarantine all personnel who had face to face contact
contact MO
75y/o male pt with diabetes who had heart surgery comes to ER with s/s of fever, hypotension, tachycardia, tachypnea, slightly AMS with elevated CBC (WBC count) and blood cultures are postive for bacteria. what is your likely Dx?
Sepsis
What are some caustive agents that lead to sepsis?
E. coli
Klebsiella
Pseudomonas Aeruginosa
Staph
Strep
N. Meningitides
Gram neg bact
What is our main treatment plan for pt who is septic?
Id the source
supportive therapy
Broad specturm IV (gentamycin and cipro)
Bed rest, Strict iso
Hospitalzation
COntact MO
What is the definition of Typhus?
a. nonfebrile gram pos, obligate intracellular, bacteria
b. febrile, gram-neg, nonobligate intracelluar, bacteria
c. Febrile gram neg, obligate intracellular, bacteria
d. Febrile gram bacilli, obligate extracellular, bacteria.
Febrile gram negative, obligate intracellular bacteria
How many types of Typhus are there?
a. 1
b. 2
c. 4
d. 3
c. 4
What are the four types of typhus?
Epidemic (louse borne) cause rickettsia prowazekii
California flea (rickettsia felis)
Endemic (murine) cause rickettsia typhi
Scrub (orientia tsutsugamushi)
What is the incubation period of typhus?
a. 2-3wks
b. 1-2wks
c. 2-10wks
d. 1-3wks
1-3 wks
Signs and symptoms of epidemic, California and Endemic Typhu presents with what?
HA, fever, chills
severe prostration
Macular rash to truck, axial , then spreading to rest of the body sparing face palms and soles (epidemic)
Maculopapular rash concentrated on the truck and fades rapidly (Murine)
How does Scrub typhus present?
Malaise, chills, gradual onset of fever, Severe headache, Backache
Site of bite (turns Black Eschar with regional lymphadentitis)
Macular rash appears primarily on truck
What are some late symptoms of typhus in the 2nd or 3rd week include?
Obtunded
Pneumonitis
Myocarditis
Encephaltis
Meningitis
Acute Abd pain
Cardiac failure
Hep
Renal failure
What is the treatment for typhus?
a. support and Doxy
b. support and PCN
c. Support and Steriods
d Support and ASA
a. doxycycline 100mg PO bid x 7 days or until two days after temp returns to normal
What is the prognosis of pt with Typhus?
a. death is great
b. good no matter what
c. depends greatly on age and immunostatus
d. depends on sex and gender
c.
Mortality rate is 10-30% with proper tx fatality and relapses are virtually eliminated
What disease is acquired most often via inhalation of feces, placenta, and milk remnants in dust and is caused by rickettsial organism Coxiella burnett.
a. Typhus
b. Qfever
c. Pfever
d. yellow fever
b.
What is the treatment for Q Fever?
Supportive care
Doxycycline 100mg PO bid
alternative therpay, Erythromycin 500mg
What are some complications that constitute 24% mortality?
a. pleural effusion
b. hepatitis
c. encephalitis
d. endocarditis
d. endocarditis
10y/o boy comes to clinic with c/o of HA, Myalgia, Rash aroudnt he wirst and ankles, diffuse abd pain, nausea and vomitting. History was mother pulled a tick off of him 4 days ago? What is the Dx?
rocky mountain spotted fever
What is the definition of Rocky mountained spotted fever?
a. nonfebrile arthorpod borne illness
b. febrile protoza borne illness
c. nonfebrile protoza borne illness
d. febrile arthropod borne illness
febrile arthropod borne illness
What is the infectious agent of RMSF?
Rickettsia rickettsii, intracellular bacterium
What is the treatment for RMSF?
Doxy 100mg PO bid until two day after fever
Alternative choic Chloramphenicol 50mg
supportive care
What is a flagellated parasitic intestinal and/or biliary tract infection?
a. e coli
b. giardiasis
c. cholera
d. salmonlea
b.
What is the predominant age range for pts with Giardiasis?
a. 5-10
b. 1-5
c. 20-40
d. 19-25
c.
What is the incubatin period of Giardiasis?
a. 1 wk
b. 1-3 wks
c. 2-4 wks
d. 5-10wks
1 to 3 weeks
What might be the only compliant with pt who has Giardiasis?
a. crampy stomach
b. nausea
c. one bulky loose stool movement a day, after Breakfast
d. constipation develops after breakfast
c.
What medication would you give to a patient with Giardiasis?
a. PCN
b. nothing
c. Tertracycline
d. Metronidazole
d. metronidazole 250mg PO TID for 7 days (CBC before and after)
What disease has rates higher in tropical and subtropical areas of poor sanitation and institutions and is protozoal parastic infection of the colon?
Amebiasis
What causes Amebiasis?
a. Anerobic histolytica
b. Aerobic entamoeba
c. Entamoeba histolytica
d. Antameoba histolytica
c.
Mode of transmission is through consumption of infected water and food, and oral fecal route
What is the incubation period of Amebiasis?
2-4wks , severe cases present in 8 days
What would be some physical findings of severe intestinal (dysenteric) Amebiasis?
Freq. BM 10-20 QD
1. Semi formed to liquid, with little fecal material
2. blood streaked, fresh or dark
3. Bits of necrotic tissue become evident
What medications do you want to avoid in pt with amebiasis, and what is the recommended treatment?
Imodium (antiperistalic agents)
Metronidazole 750mg PO TID for 10days
In sever cases admin IV
What is a febrile, flu like illness, caused by the genus Plasmodium?
Malaria
What are the four human malarias disease?
P. Falciparum
P. vivax
P. malariae
P. ovale
What is the mode of transport for Malaria?
bite of female Anopheles Mosquito
What is the incubation period of P. falciparum?
9-14days
What is the incubation period of Pmalariae?
18-40days
What are some general findings of pt with malaria?
Diaphoresis
Fatique and malaise
N/V,
Mild jaundice
Mild hepatomegaly with tenderness
Splenomegaly
Rigors
What would be some signs of pt with P. Falciparum?
a. reguarl stool, HA , and tremors
b. bloody stool, HA, seizures
c. bloody stool, HA , profused vomitting
d. Bloddy urine, HA, coma
b.
What are the two meds used for Malaria?
a. Doxycycline and PCN
b. PCN and tetracycline
c. Mefloquine and Primaquine
d. Erythromycin and PCN
c.
Mefloquine 750mg, then 500mg PO@6, 24 and 48hrs later
Primaquine 26.3mg 2 tabs PO QD for 14 days
What are some characteristics of Renal failure and Black water fever?
combo of fever and dark urine, indicating severe hemolysis following quinine treatment
What is Schistosomiasis?
Snail fever / Bilharziasis
Blood fluke infection with adult and female worms living within mesenteric or venules of veins of the host.
Humans are the main reservoirs for what type of Schistosomiasis?
a.
S. mansoni
Haematobium
What are some initial signs of Schistomiasis?
Cercarial dermatitis, then acute schistomiasis and chronic schistomiasis
What is the incubation period of Schistomiasis?
a. 1-5wks
b. 2-8wks
c. 3-4wks
d. 5-10wks
b.
What are some manifestations of Schistomiasis?
Fever
malaise
urticaria
diarrhea may be bloody
Myalgia
dry cough
What is the time frame and signs of S. mansoni and Japonicum?
begins 6 months to years after infection and presents
diarrhea, abd pain, irregular BM, blood in stool, Hard enlarged liver, Splenomegaly
What type of schistomiasis condtion is chronic and has early sym. of UTI, Freq, and dysuria followed by hematuria and proteinuria?
S. haematobium
What is the treatment plan for Schistomiasis?
Treat only give if Live OVA present
Support
Fluids
Praziquantel 20mg/kg BID for 1 day
THis disease is zoonotic and transmitted by a bite from sand flies. This polymorphic protozan disease of the skin and mucous membranes caused by the genus leishmania?
Leishmaniasis
What are the four overlapping clincial syndromes of Leishmaniaisis?
Visceral (most serious)
cutaneous (baghdad boil)
Mucocutaneous (espundia)
diffuse cutaneous
What are some important details of Visceral Leishmaniasis?
Incubation period 10days to 24 months usually 4-6 months
Fever (peaks twice daily)
chills, sweats, wt loss, cough, diarrhea, hepato-splenomegaly (
anemia
Non ulcerating nodule at the site of bite.
petechia bleeding from nose and gums
Acute or insidious onset
What leishmaniasis appears two wks to several months after bite, lesion vary from small papules, to dry plaques, and encurted ulcers that are painless. Local lymphadenopathy?
Cutaneous Leishmaniasis
A parasitic infection caused by a nematode (round worm)?
Ascariasis
What is the most common intestinal helminthes?
a. E. Coli
b. Cholera
c. Ascarias Lumbricoides
d. Ascarias Sacralricoides
c.
What are some physical findings of rAscarias?
Low grade fever
Non productive cough
blood tinged sputum
Wheezing and localized rales
Dyspnea
Substernal pain
Urticaria
What is the time frame of signs after ingestion of the eggs from the soil?
a. 1-10 days
b. 9-12 days
c. 10-20 days
d. 5-10days
b.
What are some lab results of patient with Ascarias?
CBC
Pul phase, Eosinophils may reach 30-50%, and remain high for 1months
Intestinal phase , normal Eosinophils
What is the treatment for Ascarias?
Supportive care
Mebendazole (vermox) 500mg PO single dose or 100mg PO BID for 3 days. Repeat treatment in 2wks.
Recheck stools in 3 wks, retreat if ascariasis found
What are some complication of Ascarasis?
Cholecystitis
Liver abcess
Appendicitis
Diverticulitis
A intestinal round worm disease, whose larvae migrate and become encapsulated in the muscle?
a. Ascariasis
b. Pin worm
c. Trichinosis
d. round worm
C.
Disease present world wide.
Found in virtually all warm blooded animals
What is the incubation period of Trichinosis?
a. 10-20 days
b. 5 hrs to 30 days, typcial 2-7days
c. 12 hrs -28days, typical 2-7days
d. 6hrs-20days, typical 1-10days
c.
What happens during the Muslce stage of Trichinosis?
1. End of first stage, 6wks
2. Parasitized muscle show Inflammation
3. Fever, Low grade
4. Myalgia
5.Edema and spams
6. Periorbtial and facila edema
7. Sweating, Weakness
8. Dysphagia
9. Dyspnea
10. Subconjunctival, retinal and splinter nail hemrrohages
What are some definitive lab results that will key us in on Trichinoisis?
CBC (Eosinophilia and leukocytosis, appearing in 2wks. In 3wks eosinophilia reaches 90%. Slow decline to NL over few months
Serum Muscle enzymes (cardiac enzymes)
ESR, absence of elevated ESR, indicative
What is one of the main treatments for Trichinoisis?
a. Doxy 100mg PO BID 7days
b. PCN 500mg PO TID 10days
c. Mebendazole 200-300mg PO TID 3days, F/U 400-500mg PO TID 10days
d. Tetracycline 200-400mg PO BID 2 days, f/u with Doxy 100mg PO BID 10days
c. MEbendazole
also Supportive care
24y/o male comes to clinic c/o of of perianal itiching at night. Hx shows wt loss, insomina and irritability in past 2wks. No other major findings noted.What is the likely dx?
Pinworm (Enterobiasis)
What causes Pinworms?
a. Trichinosis
b. Histomoto
c. Enterobius Vermicularis
d. Aerobic Vermicularis
C.
Man is the only host
What is the incubation period of Pinworm?
3-4wks, worm life span is 30 to 45 days.
A parasitic infection of the intestine caused by a helminthes, its widespread prevalence, moist tropics, subtropics and southeastern US.
Uncinariasis
What are some causes of Uncinariasis?
Helminthes, Ancylostoma, dueodenale, ceylanicum, caninum and Necatro americanus
Larvae penetrate skin and then gain acces to bloodstream
Once in bloodstream larvae travel to pulm. capillaries, into alveoli
Some physical findings of pts with Uncinariasis?
Ground itch, pruritic erythematous dermatitis
Pulm stage. Dry cough, Wheezing, Blood-tinged sputum, with low grade fever.
What will show if patient has heavy infection of UNCINARIASIS?
anorexia
Diarrhea
Vague abd pain
Ulcer-like epigastric pain
Pallor, and DEFORMED NAILS***
Treatment for Uncinariasis?
Mebendazole 100mg BID x3days
Repeat in 3wks
MULIT_VIT 1 tab QDx 30days
HIgh protein diet
Ferrous sulfate 200mg tab TID x2mtns, f/u with 1 tab for 4mtns
What are some complications of Uncinariasis?
a. hyperalbuminemia and Anemia
b. hypoalbuminemia and DIC
c. hypoalbuminemia and anemia
d. hyperproteinuria and thalessemia
c.
What is the definition of Tapeworm?
Genus of parasitic flatworms belonging to the class cestode, known to cause dz in man
What are the four primary causative agents known to cause disease in man (TAPEWORM)?
Taenia Saginata (beeftape worm, 59ft)
Taenia Solium (pork 21 ft)
Diphyllobothrium latium (fish 30ft)
Hymenoplis nana (dwarf 25-40mm)
What are some physical findings of Large worm infections?
may be asymptomatic
Vague GI problems (N/D, Abd pain)
systemic symptoms (Fatigue, Hunger, Dizziness)
What are some treatments for Tapeworms?
Supportive
Praziquantel 10mg/kg O single dose
Laxative 2hrs post treatment, assists in passing of worm
THis disease is predomoninatly affects men (25-55), and is barrel shaped hyphae, and is a fungus that exists in the soil, windswept sproes easily fargment and the dispersed to infect other soil, animals and humans?
Coccidiomycosis
What is the incubation period of Coccidiomycosis?
10-30 days
Asymptomatic infections is consistenet with nonspecific URI in 60% of cases
Usually asymptomatic, but what are some physical findings of Coccidiomycosis?
cough, malaise, fever, chills and night sweats, anorexia, weakness, arthralgias
Scattered rales and areas dull to percussion with auscultation.
Treatment can be extensive, but circumstances exists, then what would be the drug of choice for Coccidiomycosis?
Fluconizole 200-400mg PO QD (>6mtnhs)
Chemo for extensive problems
This disease is tranmitted thorugh inhalation of conidia, particles inhaled turn into small budding cells that are engulfed by phagocytic cells in the lung, where it then proliferates and is carried to other organs?
Histoplasmosis
What is H. Capsulatum?
dimorphic fungus that has been isolated from soil contaminated by bird or bat droppings
How is the clinical disease broken down for Histoplasmosis in different classes?
Acute , Progressive disseminated
and Chronic Progressive Pulmonary
What are some Physical findings for Acute histoplasmosis?
Fever, HA, Malaise, Pleuritic chest pain, Nonproductive cough, and wt loss
Illnes last 1week to 6mnths almost never fatal
What is the treatment for Histoplasmosis?
No drug therapy is required if asymptomatic or mild forrms of pul. dz.
Acute dz may benefit with KETOCONAZOLE 400MG QD
A multisystem disorder caused by the transmission of a spirochete from a tick?
Lyme's disease
What is the causative agent of Lyme's disease?
Borrelia burgodorferi
Pt has flu like symptoms fever, chills, myalgia with flat raised red lesion , expands over several days with central clearing. It has three stages (early localized, early Disseminated and Late persistent infection?
Lyme dz
What is the causative agent of Lyme dz?
a. nematode
b. flagellated parasite
c. Borrelia burgodorferi
d. polymorphic protozan
c. Borrelia burgodorferi
transmitted by bite of tick
What is the definition of Lyme disease?
multisystem disorder caused by transmission of Spirocehete from a tick
Where is the B. Bissettti sp found?
a. Hawaii
b. Oklahoma
c. Flordia
d. California
d.
What type of tick is found in North america?
a. Gariniii and afzelii
b. bissettii
c. serulato and serum stricto
d. giarviasis and
c.
What are some physical findings of Lyme disease?
Most pts experience cardiac or neurological manifestations
Myopericaditis, atrial or venticular arrhythmias and heart block
neurological presentation most ofetn mimics asepticmeningitis with mild HA, Stiff neck Bell's Palsy
Peripheral neuroapthy
This mycoplasmic infection accoutns for 5-10% of community acquired PNA and is 2nd most common lung infection in healthy people 5-35 yrs.?
C. Pneumoniae
What are some physical findings of Mycoplasmic Infections?
Malasie
Cough-Productive in older children, and adults and dry in infants, young children
Dyspnea-mild with exerction
Chest pain- Pleuritic and is adacnet to the infected area
What is the treatment for Mycoplasmic infections?
Macrolide (azithromycin, clarithromycin
Doxy 100mg BID

Bed rest
Pt c/o of cough, drenching night sweats, slight dyspnea with yellowis or greenish sputum and "over all not feeling well." what could be the underlying cause?
TB
What is the definition of TB?
small slow growing aerobic bacilli , with complex lipid rich cell envelope responsible for "acid fast".
What is the treatment for lyme disease?
Doxy 100mg PO BID for 21 days
alternative
AMoxicillin 500mg TID x 21 days
What if there are neurological invovlment with Lyme disease, what is the recommended treatment?
Ceftriaxone 2g QD 21 to 28days