60

Front 1

A-60. What is an "M-spike" and what is it indicitive of?

Back 1

Represents high amount of monoclonal protein present

Multiple Myeloma

Front 2

A-60. What is the path, labs, locations, and si/sx of Hypersensitivity arteritis?

Back 2

-Path: type III hypsen rxn to drugs, tumors, HCV/B, and HIV

-Labs: + p-ANCA

-Locations: small vessels mainly skin

-Si/sx: palp. purpura +/-macules, papules (butt), PAINFUL, puritc

Front 3

A-60. Henoch-Schonlein Purpura: path, epi, si/sx?

Back 3

-Path: variant of hypersen. arteritis - IgA complex in small vessel wall
-Epi: mainly kids
-Si/sx: palp. purpura (butt), arthralgias, BLOODY diarrhea, +/- glomerulonephritis

Front 4

A-60. Microscopic Polyangiitis: path, labs, si/sx?

Back 4

-Path: sim to PAN, but small vessels - usually rxn to PCN

-Labs: + p-ANCA

-Si/sx: sev. GloNF, palp. purpura, hemoptysis, hematurea, myalgia

Front 5

A-60. Thromboangitisa Obliterans (Buerger's): Path, locations, si/sx?

Back 5

Path: hyps rxn to tobacco - neutrophils surrounded by granuloma form in walls

Locations: tibal + radial arteries

S/S: destroys vessels, severe pain in distal limb - progess to gangrene

Front 6

A-60. Polymyalgia rheumatics: Path, si/sx?

Back 6

-Path: systemic manifestation of giant cells arteritis
-S/S: flu-like, very high ESR, can lead to CVA, MI, organ damage

Front 7

A-60. Wegener's Granulomatosis: path, labs, s/s?

Back 7

-Path: granulomatous develp. in vess. walls
-Labs: +c-ANCA
-S/S: sinusitis, GNF, SINUS POLYP FORMATION

Front 8

A-60. Takayasu Arteritis: path, epi, s/s?

Back 8

-Path: granulomatous vasculitis, thick aortic arch w/ gran. formations
-Epi: 15-40yo M<F
-S/S: night sweats, chest pain, wk/absent periph. pulse

Front 9

A-60. Churg-Strauss: path labs, locations, s/s?

Back 9

-Path: granulomas + PAN features + eosinophil invasion vess. wall
-Lab: p-ANCA
-Locations:BVs in skin, LUNGS/HEART
-S/S: asthma-like attck, lung infiltrates, death from coronary a. damage, comm in PMH asthma