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34 Cards in this Set
- Front
- Back
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Cotinine:
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metabolite of nicotine; used for screening
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increase in Anion gap metabolic acidosis in alcohol abuse:
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lactic acid, B-hydroxybutyric acid
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Aplastic anemia:
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chloramphenicol, alkylating agents
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Hemolytic anemia:
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penicillin, methyldopa, quinidine
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Macrocytic anemia:
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Methotrexate (most common), phenytoin, oral contraceptives, 5-fluorouracil
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Platelet dysfunction:
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Aspirin, other NSAIDs
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Thrombocytopenia:
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Heparin (most common), quinidine
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Congestive Cardiomyopathy:
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Doxorubicin, daunorubicin
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Tinnitus, verigo:
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Salicylates
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Angioedema:
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ACE inhibitors
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Maculopapular rash:
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Penicillin
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Photosensitive rash:
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Tetracycline
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Urticaria:
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Penicillin
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Hemorrhagic gastritis:
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Iron, salicylates
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Cholestasis:
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Oral contraceptives, estrogen, anabolic steroids
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Fatty change:
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amiodarone, tetracycline, methotrexate
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Hepatic adenoma:
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Oral contraceptives
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Liver necrosis:
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Acetaminophen (most common), isoniazid, salicylates, halothane, iron
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Asthma:
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Aspirin, other NSAIDs
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Interstitial fibrosis:
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Bleomycin, busulfan, nitrofurantoin, methotrexate
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Drug induced lupus:
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procainamide, hydralazine
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Arsenic:
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Diarrhea, convulsions, squamous cell carcinoma of skin, liver angiosarcoma, lung cancer
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Asbestos:
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Primary lung cancer, mesothelioma
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Benzene:
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Acute leukemia, aplastic anemia
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Carbon monoxide:
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Headache (first sign), cherry-red skin, coma
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Cyanide:
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Seizures
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Ethylene glycol:
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increased anion gap metabolic acidosis. Acute renal failure
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Isopropyl alcohol:
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deep coma
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Lead:
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Microcytic anemia with coarse basophilic stippling, nephrotoxicity in proximal tubule
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Methanol:
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Increased anion gap metabolic acidosis. Blindness due to optic atrophy
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Organophosphates:
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miotic pupils, paralysis. decreased serum and red blood cell cholinesterase levels
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Polyvinyl chloride:
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liver angiosarcoma
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Most common cause of death in burn patients:
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sepsis caused by pseudomonas aeruginosa
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UVB:
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increase in pyrimidine dimers distorts DNA helix. inact TP53. Act RAS.
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