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11 Cards in this Set

  • Front
  • Back
Incidence of ectopic pregnancy in the U.S
19.7 per 1000 pregnancies
(108,800 women)
Risk Factors
Previous ectopic
Previous PID
Previous IUD
Previous infertility tx
Previous tubal ligation
Previous tubal surgery
Signs and symptoms of ectopic pregnancy
Abdominal pain - 97-98%
Amenorrhea - 74%
Irregular vaginal bleeding - 56%
Palpable adnexal mass - 54%
sites for ectopic pregnancy
Tubal > 90%
Abdominal (1.4%)
Cervical (<1%)
Ovarian (6%)
Diagnostic tools for Ectopics
Quantitative HCG (level should double ~ every 2 days)

Progesterone level
Diagnostic tools
Ultrasound
Abdominal approach
IUP visable with HCG >6500

Vaginal approach
IUP visable with HCG >1200-1500
Diagnostic tools
Culdocentesis
Positive for non-clotting blood in 78-95% of ectopic pregnancies
Diagnostic tools
Surgery
Dilitation and curettage with frozen section, possible laparoscopy
Treatment of Ectopic
Laparoscopy
Laparotomy
Methotrexate
Instillation of hyperosmolar glucose
Candidates for methotrexate therapy
Reliable patient
Asymptomatic
HCG levels < 5000
Tubal diameter < 3cm
No fetal cardiac activity on U/S

Do not use alcohol until HCG is negative
Do not have intercourse until HCG negative
Do not use folic acid-containing vitamins
Report severe or prolonged increase in vaginal bleeding and abdominal pain
Be aware that approximately 4% of women experience tubal rupture after treatment
Correlates of repeat ectopic pregnancy
Age <= 24 years at first ectopic pregnancy
History of repeat ectopic pregnancy

Initiation of infertility work-up

Conception with an intrauterine device at index pregnancy

Pregnancy order (strongest correlate)