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9 Cards in this Set
- Front
- Back
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A-54. Four species than can cause malaria?
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Plasmodium:
-vivax -ovale -malariae -falciparum |
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A-54. DOC for chloroquine sensitive species? Pregnancy?
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Chloroquine for both
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A-54. DOC for chloroquine resistant P. falciparum?
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Quinine + one (Docy, Tetracycline, Clindamycin)
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A-54. Chloroquine MOA?
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-Transforms heme into a toxic for
-Form complexes that lyse Plasmodia and RBCs that contain it -Alkalizes its food vacuoles -Inhibits P. spp DNA synthesis |
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A-54. Metronidazole MOA, indications, SEs
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-MOA: an e- acceptor creating compounds that bind to DNA and kill the oirganism
-Ind: T. vaginalis, E. histolytica, G. lamblia |
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A-54. Nifurtimox MOA, indications, SEs, Contraindications?
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-MOA: creates radical O2 species
-Ind: Chagas disease (Trypanosoma cruzi) -SEs: ab. pain with N/V Contra: pts with G6PD def. |
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A-54. Trimethoprim-Sulfamethoxazole: Ind, MOA, SEs, Contraindications
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-Ind: Pneumocytosis jiroveci, Toxoplasma gondii
-MOA: inhibits folate manufacturing and use thus inhibits DNA -SEs: |
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A-54. DOC for round worm infection, MOA, contraindications?
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-Albendazole or Mebendazole
-MOA: inhibit microtubule-mediate glucose uptake of the worm -Conta: pregnancy, <2yo |
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A-54. Permethrin is treatment for?
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Head lice, pubic lice, and scabies.
Inhibits transmissions of nerve impulses in the organism causing permamant paralysis |
