5.28 Qbank

Front 1

1. What are Opa proteins and which organism has them?

2. There are 5 drugs involved with Sulfa allergies. What are they?

Back 1

1. adherence and antigenic proteins of n. gonorrhea

2. FACTS: furosdemie, acetazolamide, sulfonylureas, SMX, sulfasalazine, thiazides, celecoxib

Front 2

1. What organism uses Shiga toxin and what organism uses Shiga-Like toxin?

2. What is the etiology of a Charcot-Bouchard aneurysm? Where in the brain is it located?

3. Which organisms use IgA proteases?

Back 2

1. Shiga: Shigella, Shiga-like: EHEC

2. Hypertension; parenchyma

3. SHiN: Strep. pneumo, H. influ, N. Gonorrhea

Front 3

1. Why might an A-V fistula cause an intracranial hemorrhage? Where in the brain will this typically occur?

2. Which Lysosomal storage diseases are more common in Ashkenazi Jews? (3)

3. What is a cystic hygroma and what condition is it associated with?

Back 3

1. increased venous pressure leads to aneurysm; occurs most often in the hemispheres

2. Tay-Sachs, Neimann-Pick, Gaucher

3. Fluid filled cyst in the neck; Turner's syndrome

Front 4

1. Compare the amplitude/frequency of a Beta wave with that of a Delta wave?

2. Coarctation of the aorta is a biggie for Turner's. What's the other cardiac abnormality with this disease?

3. NADPH Oxidase system depends on oxygen; What natural defense system does NOT rely on oxygen?

Back 4

1. Beta: low amplitude/high frequency, Theta: high amplitude, low frequency

2. bicuspid aortic valve

3. Defensins

Front 5

1. What are the general characteristics of fibrocystic breast changes?

2. Cowdry-type inclusions are pathognomonic for what type of pathogen?

3. What is the most common malarial species?

Back 5

1. (1) fibrosis (2) cysts (3) epithelial changes (increased glands or ducts)

2. Herpesvirus

3. p. vivax

Front 6

1. Which is the most serious plasmodium species?

2. Why would a patient with CNVII paralysis have hyperacousis?

Back 6

1. plasmodium falciparum

2. Loss of innervation to Stapedius muscle in ear.

Front 7

1. What are the timeframes for phase I, II, III starvation and what energy is used during each?

2. Describe the organization of the important structures in the brachial fossa?

3. The most common mutation resulting in trisomy is what?

Back 7

1. I: liver glycogenolysis (up to 24 hrs), II: liver gluconeogenesis (at 36 hours), III: ketones/FFA (1 week)

2. Lateral → Medial (TAN): biceps Tendon, brachial Artery, medial Nerve

3. Robertsonian Translocation: two acrosomal chromosomes recombine losing the short ends

Front 8

1. Where do the cells come from for re-epithelialization of an abrasion that did not include the dermis?

2. What is mean arterial pressure composed of? (HINT: MAP equation?)

3. What is the difference between bullous pemphigus and pemphigus vulgaris with respect to the area affected by each?

Back 8

1. stem cells in hair follicle

2. MAP=CO X TPR

3. bullous pemphigus spare the oral mucosa; pemphigus vulgaris does not spare the oral mucosa

Front 9

1. Superior Vena Cava syndrome is what? And what tumors cause it?

2. What is the first-line class of drugs for diabetes not controlled with diet and exercise?

3. Fistulas are a characteristic of Crohn's disease. Why and how does it present?

Back 9

1. compression of SVC by a lung tumor

2. sulfonylureas

3. transmural inflammation causes a connection with the bladder: multiple UTIs

Front 10

1. A patient with homocysteinuria has physical features that appear like what other disease?

2. WHERE and ON WHAT proteins do penicillins act?

Back 10

1. Marfans

2. penicillin binding proteins responsible for the cross-linking of PTG are transmembrane proteins in the cell membrane

Front 11

1. Diagram the homocysteine pathway with appropriate enzymes? Also, how is this condition treated?

2. Compare the emboli in which you would see splinter hemorages versus a PE?

3. Compare the antigens produced from a polysaccharide vaccine versus a conjugated protein vaccine? Why is there a difference?

Back 11

1. SEE SHEET; treated with ↑cysteine/↓methionine

2. splinter: arterial, PE: venous

3. polysac: only IgM, protein: IgG (T cells required for isotype switching; T-cells stimulated by proteins in MHC groove

Front 12

1. What are the enterotoxigenic bacteria that work via cAMP and describe their mechanisms?

Back 12

1. vibrio: Gs, ETEC: Gs, pertussis: Gi, bacillus: toxin is an AC

Front 13

1. What condition results in the complete lack of fusion of process vaginalus versus partial lack of fusion?

2. What is associated with "owl's eye" inclusion body?

3. Compare locations of the AV node and the His Bundle?

Back 13

1. complete: congenital hernia, partial: hydroceole

2. CMV

3. AV: intratrial septum, His: intraventricular septum

Front 14

1. Psuedohypoparathyroidism is associated with shortened 4th/5th fingers; What other condition is also like this?

2. Where is the cingulate gyrus?

3. Which cell contains high levels of major basic protein?

Back 14

1. sickle cell

2. runs parallel to and is just above the corpus callosum

3. eosinophils

Front 15

1. What is the repeat sequence in Freidreich's ataxia?

2. Describe the effects of efferent/afferent artery dilation/constriction on RPF/GFR?

Back 15

1. GAA

2. Constrict A: ↓RPF/↓GFR, Dilate A: ↑RPF/↑GFR, Constrict E: ↓RPF/↑GFR, Dilate A: ↑RPF/↓GFR

Front 16

1. What is the repeat sequence in Myotonic Dystrophy?

Back 16

1. CTG

Front 17

1. What is the repeat sequence in Fragile X?

Back 17

1. CGG