Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
30 Cards in this Set
- Front
- Back
|
morphine |
strong opioid µ-receptor agonist >> K-receptor |
|
|
methadone |
strong opioid µ-receptor agonist |
|
|
fentanyl |
strong opioid µ-receptor agonist |
|
|
hydromorphone |
strong opioid µ-receptor agonist
- more potent than morphine |
|
|
oxymorphone |
strong opioid µ-receptor agonist
- more potent than morphine |
|
|
meperidine |
strong opioid µ-receptor agonist
- anti-cholinergic effects |
|
|
sufentanil |
strong opioid µ-receptor agonist >> δ,K-receptor |
|
|
alfentanil |
strong opioid µ-receptor agonist |
|
|
remifentanil |
strong opioid µ-receptor agonist |
|
|
levorphanol |
strong opioid µ-receptor agonist |
|
|
codeine |
partial opioid µ-receptor agonist
- for pain and cough |
|
|
hydrocodone |
partial opioid µ-receptor agonist |
|
|
oxycodone |
partial opioid µ-receptor agonist |
|
|
propoxyphene |
partial opioid µ-receptor agonist |
|
|
buprenorphine |
partial µ-agonist, K-antagonist |
|
|
nalbuphine |
K-agonist, µ-antagonist |
|
|
butorphanol |
K-agonist, partial µ-agonist/antagonist |
|
|
pentazocine |
K-agonist, partial µ-agonist/antagonist |
|
|
dextromethorphan codeine |
poorly understood moa
antitussive |
|
|
naloxone |
opioid antagonist at µ, δ, K receptors
- opioid overdose |
|
|
naltrexone |
opioid antagonist at µ, δ, K receptors
- opioid overdose and maintenance |
|
|
nalmefene |
opioid antagonist at µ, δ, K receptors
- opioid overdose |
|
|
alvimopan |
potent peripheral µ antagonist
- no effect on morphine analgesia (no CNS entry) |
|
|
methylnaltrexone |
potent peripheral µ antagonist
- no effect on morphine analgesia (no CNS entry) |
|
|
tramadol |
weak µ agonist, moderate SERT, weak NET inhibitor
- moderate pain adjunct |
|
|
tapentadol |
weak µ agonist, moderate SERT, weak NET inhibitor
- moderate pain adjunct |
|
|
ziconotide |
blocks presynaptic N-type VG Ca+ channels
- severe, refractory chronic pain |
|
|
loperamide |
µ agonist in enteric nervous system
- diarrhea |
|
|
diphenoxylate |
µ agonist in enteric nervous system
- diarrhea
- high doses can cause CNS opioid effects and toxicity |
|
|
difenoxin |
µ agonist in enteric nervous system
- diarrhea |
