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20 Cards in this Set
- Front
- Back
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flux is proportional to: |
flux=permability x surface area x (conc. difference) |
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immature PMNs have... |
decreased Fc receptor (CD16) so they are not as efficient at phagocytosing opsonized bacteria |
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what is TdT |
marker for ALL TdT is a DNA polymerase |
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biologically active form of pantothenic acid |
CoA |
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denial vs fantasy |
denial: behaving as if an aspect of reality does not exist fantasy:substituting imaginary scenarios |
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aspergillus vs mucor |
aspergillus: acute angle and septate mucor: wide angle and non-septate |
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topical vitamin D analogues can be used to treat? |
psoriasis: eg calcipotriene. Inhibit keratinocyte proliferation and stimulate keratinocyte differentiation via activation of vitamin D receptor (transcription factor) |
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dopamine agonists used in parkinson dz |
ergot: bromocriptine and pergolide non-ergot: pramipexole and ropinirole |
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associated with body fat redistribution |
HAART therapy |
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comt inhibitors used in PD |
entacapone: peripheral tolcapone: peripheral and central |
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pioglitazone |
TZD decreases insulin resistance by binding to PPARgamma -> increases levels of adiponectin. main side fx is fluid retention and edema |
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fungal drugs that bind to ergosterol |
amphotericin B and nystatin |
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terbinafine moa |
binds fungal squalene epoxidase, which disrupts synthesis of ergosterol |
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who should obtain informed consent? |
the physician performing the procedure |
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volume of distribution |
vd=amt in body/plasma drug conc. =mass/conc. =volume of distribution |
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clearance (pharmacokinetics) |
the vol. of plasma cleared of drug per unit of time CL= (rate of elim. of drug)/(plasma drug conc.) = (vol. of distribution) x (elimination constant) "CLa Vi Kel" |
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loading dose |
(Cp x Vd)/F "upload your CV" |
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maintenance dose |
(Cp x CL x dosage interval)/F "maintain the dose w/ CC of the drug" |
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zero order elimination drugs |
phenytoin, etoh and aspirin |
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used to reduce bladder spasms and urgency |
oxybutynin, -fenacin (darifenacin), -terodine (tolterodine) |
