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15 Cards in this Set

  • Front
  • Back

HLA associations


A3


B27


DQ


DR2


DR3


DR4


DR5

"HFE and A3"


B27 = PAIR


DQ is celiac dz "8 some gluten? DQ'd from entering body"


DR2 "Two MS sisters sleeping on the hay (hay fever) in a Goodpasture"


DR2/3 "2, 3, SLE! 3, 4 pee galore (diabetes I)"


DR3 "Tale of the 3 graves"


DR4 "R4 looks like RA"


DR5 "motocross (hashimoto) high 5" and pernicious anemia

autoAb in polymyositis/dermatomyositis

Jo-1, SRP, Mi2

most drug ODs in the US?

prescription drugs, specifically opioids

vit A OD

papilledema (increased intracranial P)


hepatotoxicity

cetuximab

targets EGFR, used in colon and head/neck CA

mediators of pain

bradykinin and PGE2

key mediators of vasodilation in acute inflammation

histamine, prostaglandins, bradykinin

bradykinin

vasodilation and vascular permeability (like histamine)


pain (along w/ PGE2)

what collagen synthesis events happen outside the cell?

(collagen secreted as procollagen in triple helices)




procollagen peptidases cleave procollagen N and C terminals... becomes tropocollagen... spontaneous assembly into fibrils... crosslinking by lysyl oxidase

hep d derives it's envelope and surface Ag from?

envelope from host and surface Ag (embedded in membrane) from Hep B

fx of inhaled anaesthetics

increased ICP, repiratory and CV depression

high prolactin during pregnancy is prevented from causing lactation by?

estrogen and progesterone

Wiskott Aldrich

"Wiskers the cat w/ and x shaped (X linked) bow TIE (thrombocytopenia, infections, eczema) drank all the Milk (decreased IgM)"

fidaxomycin

tmt resistant c. diff. Given orally and has poor systemic absorption. Inhibits Rna polymerase and is bacteriocidal.

atypical depression

mood reactivity (ie mood gets better in response to good things) (vs MDD where there is no improvement in mood)


also:


heavy feeling in arms/legs


rejection sensitivity


increased appetite and sleep


Treat w/ MAOs