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16 Cards in this Set
- Front
- Back
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gilbert synd |
defect in glucoronosyltransferase... inc. indirect bili, NL direct bili |
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I cell dz |
lack of enzyme to tag vesicles w/ Mannose 6P leads to extra cellular secrection of vesicle contents instead of targeting for lysosome. Lack of enzymes in cell, but enzymes will be found extracellularly. Think "can't keep the contents In the cell" |
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cricothyroid m. innervation |
ext. laryngeal n. (all other musc. from rec. lar. n) "to make pitch higher you need the n. from higher" |
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glucocorticoids fx on collagen synth |
inhibits. (hence striae and poor wound healing in Cushings) |
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selection bias |
non-random assignment to study groups |
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sx of TCA od |
coma (also resp. depression -> resp. acidosis), convulsions, cardiotoxicity (arrythm., tachycar.) |
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PA nodosa hypersensitivity |
type III (hep B-Ab complexes deposit in medium sized vessels) |
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Job's synd. |
"PMNs can't get to their jobs" (problem w/ PMN chemotaxis). FATED: coarse or leonine facies, cold staph abscesses, retained primary teeth, increased IgE, and dermatologic problems [eczema]. |
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Wiskott–Aldrich syndrome |
Wiskott–Aldrich syndrome (WAS) is a rare X-linked recessive disease characterized by eczema,thrombocytopenia (low platelet count), immune deficiency, and bloody diarrhea (secondary to the thrombocytopenia). It is also sometimes called the eczema-thrombocytopenia-immunodeficiency syndrome |
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small jaw, low set ears, clenched fists |
trisomy 18 (edward) |
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where is cardiolipin found |
inner mitoch membrane (and hearts have lots of mitochondria) |
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pos. pred val. |
"how good is the test?" true pos./all the test pos. |
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% of people with a dz that will test + |
sensitivity (eg in lupus the ANA is very sensitive in that all lupus pts have a + ANA, but other dz can have + ANA as well, such as RA) |
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% of people w/o a dz that will test - |
specificity (a really specific test will be + only if the person has that dz) |
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turcot synd. |
FAP+ CNS tumors ("turncot wears a turban" (CNS)) |
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sign of pancreatic CA |
Courvoisier sign: jaundice and palpable enlarged non-tender gall bladder |
