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297 Cards in this Set

  • Front
  • Back
Motor Control Systems influence
1. Tells the LMN what to do
2. LMN to fire or not to
Two Major Motor Systems and Function
Pyramidal: Initiated, voluntary skeletal muscle activity
Extrapyramidal: Involuntary skeletal muscle activity
Supplemental Motor Areas
(Pyramidal System) are located in what lobe and areas?
-Frontal Lobe
-Anterior to Primary Motor Cortex
-Superior to PreMotor Cortex
Supplemental Motor Area finessed movements play what three roles?
- Important for initiation of movement
- Orientation of the eyes and head
- Planning sequential and bi-manual movements
Supplemental Motor Area goes to...
- Interacts with pre-central gyrus (Pre-motor Cortex)
- Sends UMN to CN motor Nuclei
- Ventral Horns of spinal Cord where UMN synapse with LMN
Premotor Area is part of what system?
Pyramidal system
Premotor Area is found in what lobe of the brain?
Frontal Lobe
Is the Broca's Area anterior or posterior to the pre-central gyrus?
Anterior
Functionally, the pre-motor area is an association area that controls
Trunk, Pelvic, and Pectoral Girdle Musculature
(Helps with changing your posture)
T or F The pre-motor area is involved with anticipatory postural control and adjustments
True
What area interacts with pre-central gyrus, as well as sending UMN to the CN nuclei in the brainstem and sends UMN to ventral horns
Pre-motor Area
Broca's Area is part of what system
Pyramidal System (voluntary)
Broca's area is found in what lobe of the brain?
Frontal Lobe
Is Broca's area anterior or posterior to the pre-central gyrus?
Anterior
Functionally the Broca's area is an association area that functions as...
Primary function is to instigate speech (Tell the muscles what to say)
What are the two corticofugal motor tracts?
- Corticospinal Tract
- Corticobulbar Tract
Is the corticospinal tract part of the pyramidal or extrapyramidal system?
Pyramidal (voluntary skeletal)
The cell bodies of the corticospinal tract are found in which gyrus and lobe of the brain?
Pre-central Gyrus / Frontal Lobe
What cranial nerves do not have motor input?
CN I, II, VIII
What two Cranial Nerves have unilateral projection patterns?
CN VII & XII
What are the two motor functions CNIII?
1. Innervates extrinisc eye muscles & levator palpebrae superioris
2. Innervates iris and ciliary body
What complex contains cell bodies of LMN in tegmentum of the midbrain for CNIII for it's function of innervating extrinsic eye muscles and levator palpebrae superioris?
Oculomotor Nuclear Complex
The preganglionic parasympathetic neurons that innervate the iris and ciliary body (CNIII) begin in what nucleus and location?
Edinger-Westphal Nucleus
The synapse between the pre and post ganglionic parasympathetic neurons that innervates the iris and ciliary bodies (CNIII) are located in what ganglia?
Ciliary Ganglia
Does the Trochlear Nerve (IV) receive bilateral or unilateral input from UMN in the corticobulbar tracts?
Bilateral input
What muscle(s) does the Trochlear nerve (CN IV) innervate and where in the tegmentum of the midbrain are the cell bodies of LMN located?
- Superior Oblique Extrinsic Eye Muscle
- Trochlear Motor Nucleus
What cranial nerve innervates the superior rectus, medial rectus, inferior rectus, and inferior oblique (extrinsic) muscles?
Oculomotor Nerve (III)
The muscles of mastication (medial & lateral ptyergoid, masseter, and temporalis muscles) are innervated by what cranial nerve?
Trigeminal Nerve (V)
Does the Trigeminal Nerve (V) receive input bilaterally or unilaterally from UMN in the corticobulbar tract?
Bilateral
In what nucleus are the cell bodies of the LMN of CN IV, tegmentum of the midbrain?
Trochlear Motor Nucleus
Motor nucleus of V contains cell bodies of LMN located in what area?
Tegmentum of the Pons
Where does the Trigeminal Nerve decussate?
Pons at the motor nucleus of V
What muscle does the Abducens nerve innervate?
Lateral Rectus Extrinsic Eye Muscles
Does the Abducens nerve receive bilateral or unilateral input from UMN in the corticobulbar tract?
Bilateral
Name the nucleus and where are the cell bodies of the LMN of CN VI are located?
Abducens Motor Nucleus in the tegmentum of the Pons
What are the 2 motor functions of the Facial Nerve?
1. Innervates the muscles of facial expression.
2. Innervates the submandibular, sublingual, and lacrimal glands (parasympathetic function)
The Facial Nerve is divided into upper and lower portions in the corticobulbar tract. Is the upper bilateral or unilateral input? Lower?
Upper - Bilateral input
Lower - Unilateral input
Facial Motor Nucleus contains what and is located where?
Facial Motor Nucleus contains cell bodies of the LMN of the CN VII and located in the tegmentum of Pons
What nucleus located in the tegmentum of the medulla will you find preganglionic parasympatheric neurons for CN VII?
Salivatory Nuclei
Regarding CN VII, where due the postganglionic parasympathetic neurons and preganglionic parasympathetic neurons synapse?
Submandibular and Pterygopalatine Ganglia
What are the 2 motor functions of CN IX?
1. Innervates the stylopharyngeus muscle of pharynx
2. Innervates parotid gland (parasympathetic)
Where are the cell bodies of LMN for the glossopharyngeal nerve found and name of nucleus?
Found in tegmentum of Medulla in the nucleus called Nucleus Ambiguous
Does CN IX have bilateral or unilateral input from the corticobulbar tract?
Bilateral
Is the CN IX that innervates the parotid gland involved with the corticobulbar tract?
No
CN IX innervation of the parotid gland has preganglionic parasympathetic neurons found in what nucleus and where?
Salivatory Nuclei in the tegmentum of the Medulla
What synapses in the Otic Ganglia in the neck?
Pre and Post Ganglionic Parasympathetic Neurons of CN IX
What are the two motor functions of the Vagus Nerve?
1. Innervates the muscles of the larynx, pharynx, and soft palate
2. Innervates the viscera of the thorax, abdomen, and pelvis
Does CN X input from the corticobulbar tract give input bilaterally or unilaterally?
Bilaterally
The Nucleus Ambiguous contains cell bodies of LMN in the tegmentun of the Medulla for what CN?
CN IX & XI
Where are the Vagus Nerve preganglionic parasympathetic neurons located and name of nucleus?
Dorsal Motor Nucleus in the tegmentum of Medulla
Where do CN X pre and post ganglionic parasympathetic neurons synapse?
Numerous Ganglia
The Spinal Accessory Nerve receives bilateral input from what tract?
Corticobulbar Tract
LMN for CN XI begin in two separate nuclei?
- Spinal Motor Nucleus (Cervical Portion)
- Nucleus Ambiguous
(Cranial Portion)
The Spinal Motor Nuclei are located in what area?
Rostral Cervical Regions of Spinal Cord
The Nucleus Ambiguous Nuclei are located in what area?
Tegmentum of the Medulla
The Cervical portion of CN XI innervates what muscles?
SCM & Trapezius
The Cranial portion of CN XI innervates what muscles?
Intrinsic Laryngeal Muscles
Does the Hypoglossal Nerve receive input from corticobulbar tract bilaterally or unilaterally?
Unilaterally
Hypoglossal Nerve cell bodies of LMN are found in what nucleus and where?
Hypoglossal Motor Nucleus in the Tegmentum of Medulla
What are the four modulatory Descending Motor Tracts?
1. Rubrospinal Tract
2. Tectospinal Tract
3. Vestibulospinal Tract
4. Reticulospinal Tract
What does the Modulatory Descending Motor Tracts due to subserve the corticospinal tract?
The tracts refine and finesse the activity of LMN receiving input from the UMN
What nucleus contains the cell bodies of UMN for the Rubrospinal Tract?
Red Nucleus of the Midbrain
(Decussates here)
Where does the Rubrospinal Tract terminate?
Ventral Horn of the Spinal Cord
Does the Rubrospinal Tract excite or inhibit flexor activity? Extensor activity?
Flexor Activity - Excite
Extensor Activity - Inhibit
What nucleus contains the cell bodies of UMN of the Tectospinal Tract?
Superior Colliculus of the Midbrain (Decussates)
Where does the Tectospinal Tract terminate?
Ventral Horns of the Upper Cervical Spinal Cord
True or False Tectospinal Tract causes reflex postural movements of the head, neck, and upper extremities in response to visual stimulus?
True
What nucleus and where do the cell bodies of the UMN originate for the Vestibulospinal Tract?
Vestibular Nuclei in the Tegmentum of Pons (No Decussation)
Where does the Vestibulospinal Tract terminate?
Ventral Horn of the Spinal Cord
What does the Vestibulospinal Tract do?
Involved in "righting reflexes"
The Reticulospinal Tract has cell bodies of UMN in what nuclei located in the ?
Multiple Reticular Nuclei in the brainstem
Does the Reticulospinal Tract have ipsilateral or contralateral function?
Ipsilateral
Does the Reticulospinal Tract excite or inhibit extensor activity? Flexor activity?
Extensor Activity - Excites
Flexor Activity - Inhibits
True or False
Damage can occur anywhere along the Corticospinal Pathways?
True
What are the six classical signs of UMN damage in relation to the Corticofugal Tracts?
1. Paresis
2. Paralysis
3. Exaggerated DTR: Hyperreflexia
4. Clonus
5. Spastic Paralysis
6. Hypertonia
UMN damage causing muscle weakness because skeletal muscles are receiving less input.
Paresis
UMN damage causing loss of movement; large range of loss because of less input; can mean loss of function.
Paralysis
(UMN Paralysis)
UMN damage causing simple reflex arcs to be more active.
Exaggerated DTR: Hyperreflexia
UMN damage causing spasms with alterations of contractions and relaxation in rapid succession of antagonistic and agonistic muscles (hyperreflexia of spinal reflexes)
Clonus
UMN damage characterized by involuntary contraction of one ore more muscles w/loss of function. (Hallmark of UMN Lesion)
Spastic Paralysis
UMN caused by an increase of muscle tone.
Hypertonia
True or False
The corticospinal tract has ipsilateral effects before decussation and contralateral effects after the decussation.
False
True or False
Damage to the UMN causes the LMN to not get supraspinal instruction via the corticospinal tract not influencing the activity)
True
Name the test that runs an object up the lateral side of the foot testing for UMN lesion.
Babinski test
What will the patient do if have a Normal Babinski?
Toes will plantarflex
What will the patient do if have a Positive Babinski?
Toes will dorsiflex and the great toe fans
What are the six classical signs of LMN damage in the corticofugal motor tracts.
1. Paresis
2. Flaccid Paralysis
3. Hypotonia
4. Decreased or Absent DTR
5. Fibrillations/Fasciculations
6. Atrophy
What cranial nerves are involved with LMN Paralysis?
CN III, IV, V, VI, VII, IX, X, XI, XII - always ipsilateral
Can LMN be alpha, gamma, or both motor neurons?
Both
Alpha or gamma motor neurons can be found in?
1. Motor Nuclei of CN w/motor function
2. Ventral Horns of the Spinal Cord
LMN damamge can cause weakness, not innervating skeletal muscles resulting in a dramatic weakness.
Paresis
LMN damage causes total loss of muscle tone with resultant loss of function
Flaccid Paralysis
LMN damage causes decreased muscle tone because its lost the source that makes the muscle contract
Hypotonia
LMN damage causes wiped out LMN part of the reflex are affecting deep tendon reflexes.
Decreased or absent DTR
LMN damage causes reduction in size of skeletal muscle as a result of decreased tone (decreased actin and myosin fibers)
Atrophy
Can you get atrophy with UMN damage in the corticofugal motor tract?
No, Only in LMN because with UMN damage the muscle cells are still contracting but it is spastic
LMN damage causes spontaneous activity of skeletal muscle, physiological response not neurological.
Fibrillations/Fasciculations
Will symptoms with LMN damage in the corticofugal motor tract always be ipsilateral or contralateral and why?
Ipsilateral, there is no decussating therefore it will always be ipsilateral
What 5 categories do responses of LMN damage fall into?
1. Spinal reflex responses
2. Rhythmic patterned movements
3. Become central pattern generators (CPG)
4. Recicprocal inhibitory neural circuits
5. Cell level
True or False
Rhythmic patterned movements are predictable involuntary movements involved with specific motor activities that can be hardwired from birth or developed through life.
True
When movements become central pattern generators (CPG) are they voluntary or involuntary movements?
Involuntary movements
Where are CPGs set up and remembered in?
1. Basal Ganglia
2. Spinal Cord
3. Brainstem
4. Cerebellum (the most)
True or False
Reciprocal inhibitory neural circuts are NOT the physiological substrates for rhythmogeneisis in CPG systems.
False - They are
On a cellular level do membranes of the neurons involved with CPGs have NMDa receptors which bind with glutamate?
Yes, adds a rhythmic characteristic to the membranes
Spinal cord reflexes are segmental in nature and may involve one or more segments at a time. Does this cause communcation between the segments?
Yes, it's how one segment knows what another one is doing.
Where are spinal cord reflexes that involve propriospinal loops/circuits?
Gray Matter
What are the two tracts in regards to Spinal Cord Reflexes that modulate supraspinal influences?
- Rubrospinal Tract
- Reticulospinal Tract
Rubrospinal tract modifies UMN system and is biased toward ________activity.
flexor
Reticulospinal tract found in the ventral horns of the spinal cord are biased toward __________ activity.
extensor
What are the four fundamental anatomical parts of a spinal cord reflex?
1. Receptor Organs on distal end of a sensory organ
2. Afferent sensory neuron with receptor at distal end.
3. An efferent motor neuron with an effector organ at its distal end.
4. An effector organ
To break the a spinal cord reflex, which fundamental anatomical parts must be involved?
Receptor organ on either afferent sensory neuron or efferent motor neuron, afferent sensory neuron, or efferent motor neuron
What are flexor reflexes (protective reflexives) activated by?
Type III (A-delta) & IV (C fibers)
When you step on a tack, what pulls your foot up?
Flexor reflexes involving Type III and Type IV fibers
What causes a DTR/ myotactic/stretch reflex?
The contraction of agonistic and synergistic muscles following the stretching of agonistic muscles.
The DTR/myotactic/stretch reflex activates what fiber type(s)?
Type Ia
What path does the DTR/myotactic/stretch reflex take?
Travel to dorsal root to then synapse w/LMN that returns to same muscle that was stretched
What is the purpose of the DTR/myotactic/stretch reflex?
It maintains upright posture and muscle tone.
How does the DTR/myotactic/stretch reflex move thru the system?
Gravity pulls on skeletal muscles then causes them to stretch then activates sensory neurons then go back to spinal cord then synapses with LMN then goes back out then causes the skeletal muscle to contract
True or False
Partial muscle contraction allows us to maintain posture and muscle tone.
True
DTR/myotactic/ stretch reflex use 1st order sensory neurons with what type of receptor organs?
Muscle spindle fibers
Is the DTR/myotactic stretch reflex considered a proprioceptive reflex?
Yes,because it involves skeletal muscles
Is the DTR/myotactic/stretch reflex a 2 or more neuron pathway?
It is a two neuron pathway
The DTR/myotactic/stretch reflex is a 2 neuron pathway involving what?
Receptor organs and Synapses
What structures allows the muscle spindle fibers to measure length and rate of change of length?
Extrafusal fibers
What are the cells in the muscle spindle fibers called?
Intrafusal fibers
Are intrafusal fibers modified extrafusal fibers?
yes
What are the three types of intrafusal fibers?
1. Dynamic Nuclear Bag (Ia) (most important)
2. Static Nuclear Bag(II)
3. Nuclear Chain Fiber(II)
True or False
All of the intrafusal fiber types function to differentiate between static and dynamic change in length and rate of change in length of skeletal muscle (extrafusal fibers)
True
Are intrafusal fibers parallel or perpendicular to extrafusal fibers?
Parallel
Are intrafusal fibers mechanical stretch receptors?
Yes because they measure stretch
Where are the noncontractile portions of the intrafusal fibers found?
Located in the middle of the intrafusal fiber
What does the annulospiral ending do and where is it found?
Distal end of the intrafusal fiber that is wrapped around the noncontractile portion
What is the primary sensory ending in the skeletal structure?
Annulospiral ending
What type of energy registers the length or rate of change of length in the intrafusal fiber in the annulospiral ending?
Mechanical Energy
Where are the flower spray endings located?
Located laterally on either side of the annulosprial ending on the noncontractile portion of the intrafusal fibers.
What Type of fibers are flower spray endings?
Type II Sensory Neurons
Type Ia fibers (annulospiral endings) monosynaptically (synapses 1 times)synapse in spinal cord with alpha motor neuron which innervate the same muscles (homonymous) or synergistic muscle (heteronymous).
True or False
True
Type II fibers (flower spray ending) only synapse (monosynaptically) with alpha motor neuron of the same muscle (homonymous).
True or False
True
What type of reflex causes autogenic inhibition?
GTO Reflex/inverse reflex/tendon reflex.
Encapsulated mechanoreceptors at the junction between muscle fibers and tendons are called
Golgi Tendon Organs
Are Golgi Tendon Organs involved with GTO Reflexes?
Yes
What are the efferent components of the DTR/myotactic/stretch reflex?
Alpha Motor Neurons (LMN)
Where are the cell bodies of the Alpha Motor Neurons?
Ventral Horns
What do the alpha motor neurons innervate?
Extrafusal fibers - contraction of muscle can either produce movement or increase muscle tone
What type of cells get inhibition of antagonistic muscle activity and what is this called?
- Renshaw cells
- Reciprocal Inhibition
Is the GTO reflex/inverse reflex/tendon reflex considered proprioceptive reflex, why or why not?
Yes because it involves muscles and tendons
What type of fiber are GTO reflex/inverse reflex/tendon reflex?
Type Ib
What does the GTO reflex/inverse reflex/tendon reflex measure?
It measures tension and rate of change of tension in the tendon.
What is the major function of GTO reflex/inverse reflex/tendon reflex?
Adjust muscle activitiy in concert with information from muscle spindle and descending controls.
How does the GTO reflex/inverse reflex/tendon reflex prevent tearing of the muscles with extreme muscle contraction?
Inhibits the contraction of the muscle, keeping the antagonistic muscle from being excessively stretched or contracted. Type Ib synapse with Renshaw cells to inhibit alpha motor neuron activity
Can the GTO reflex/inverse reflex/tendon reflex cause a loss of muscle tone and function?
Yes; autogenic inhibition=automatic inhibition
What three primary factors affect muscle tone?
1. Intrinsic characteristic of extrafusal fibers.
2. Gravity pulling on skeletal muscle and activating stretch reflex
3. Gamma bias due to supraspinal descending pathways influencing what gamma motor neurons are doing.
What do gamma motor neurons do?
Alter the sensitivity of the muscle spindle by altering the length of the intrafusal fibers and the tension they exert.
Are gamma motor neurons larger or smaller than alpha motor neurons?
Smaller
What cranial nerves can cause diplopia and what is it?
CN III, IV, & XI
Double vision caused by paralyses of the extrinsic eye muscles
What cranial nerves can be involved with strabismus and what is it?
CN III, IV, XI
Eyes are crossed and not synchronized during movement due to extrinsic eye muscles not properly innervated or muscle damage
What is mydriasis and why does it happen?
A dilated pupil due to loss of preganglionic parasympathetic fibers in CN III (loss of input to iris in the Edinger-Westphal Nucleus)
What is anisocoria and why does it happen?
Pupils of unequal size due to one iris being innervated and one not due to loss of preganglionic parasympathetic fibers of CN III
Is mydriasis found in the dilated eye?
Yes
If you shine a light in right eye and do not get a direct reflex in right eye but get consensus reflex in left eye, what is possibly happening?
CN II of right eye is in tact and sending sensory info
Assume Right CN III is not working
Shine a light in left eye and do not get direct or consensus reflex, what is happening?
Left CN II is not working
What physical sign results in double vision due to paralysis of extrinsic eye muscles?
Diplopia
What physical sign of LMN paralysis to CN III that causes drooping of upper eyelid because of dysfunction of what muscle?
Ptosis; levator palpebrae superioris
Trochlear CN synapses as a LMN with what and where?
UMN of the corticobulbar tract in the Trochlear motor nucleus in the midbrain
What CN is involved with paralysis of the superior oblique extrinsic eye muscle?
Trochlear CN IV
What are three branches of trigeminal nerve and are they motor, sensory, or mixed?
V1-sensory (opthalmic)
V2-sensory (maxillary)
V3-mixed (mandibular)
Where and with what do the LMN of V3 synapse with?
Motor Nucleus of V in tegmentum of pons(decussates); UMN in corticobulbar tract
What nucleus does the abducens cell bodies originate in and what does it innervate?
Abducens motor nucleus; lateral rectus extrinsic eye muscle
Can either or both diplopia and adducted eye happen with damage to LMN of CN VI
They can both happen
What are the two sensory functions of Facial CN?
1. Chorda tympani nerve innervates the anterior 2/3 of tongue for taste
2. Posterior auricular nerve innervatges the external ear for general sensations
What are the two motor functions of Facial CN?
1. Innervates muscles of facial expression
2. Innervates Submandibular, Sublingual, and Lacrimal glands
The motor portion of the CN VII that innervates muscles of facial expression are divided into upper and lower portions. Which portion is has bilateral and which has unilateral synapse with the corticobulbar tract and in what nucleus and where?
Upper has BL UMN Corticobulbar Tract.
Lower has UL UMN Corticobulbar Tract
Both synapse the Facial Motor Nuclei in the Pons.
Upper portion of CN VII that synapses with UMN in Facial Motor Nuclei innervates what?
Innervates muscles above horizontal line of the eye orbit.
Lower portion of CN VII that synapses with UMN in Facial Motor Nuclei innervates what?
Innervates muscles below horizontal line of the eye orbit.
The portion of CN VII that innervates the submandibular, sublingual, and lacrimal glands is involved with sympathetic or parasympathetic nervous system?
Parasympathetic of ANS
The motor portion of CN VII that innervates the submandibular, sublingual, and lacrimal glands is controlled by what?
Either Reflex or Hypothalamus
Where are the preganglionic parasympathetic neurons for motor portion of CN VII located?
Salivatory Nuclei in Tegmentum of Medulla
Where do the pre and post parasympathetic neurons synapse that innervate the submandibular and sublingual glands in CN VII?
Submandibular Ganglia
Where do the pre and post parasympathetic neurons synapse that innervate the lacrimal gland in CN VII?
Pterygopalantine Ganglia
Lesion in CN VII can cause?
1. Bell's Palsey
2. Loss of Tearing
3. Loss of Salivation
4. Loss of Taste Perception to the anterior 2/3 of tongue
In relation to CN VII, are LMN Paralysis, Loss of Tearing, Loss of Salivation, and Loss of Taste Perception contralateral or ipsilateral?
All Ipsilateral
The Vestibulochochlear Nerve is made up of what two nerves and were do they originate?
1. Auditory Nerve - Organ of Corti
2. Vestibular Nerve - Semicircular Canals
What are the two possible results from lesions with CN VIII and are they ipsilateral or contralateral?
1. Loss of hearing (auditory nerve)- ipsilateral
2. Loss of Equilibrium Input (vestibular nerve) - ipsilateral
What are the two motor functions fo the Glossopharyngeal Nerve?
1. Innervates the stylopharyngus muscle of pharynx
2. Innervates the parotid gland (parasympathetic)
What nuclei do the UMN and LMN of CN IX synapse in and what muscle does it innervate?
Nucleus Ambiguous of Tegmentum of Medulla; Stylopharyngus Muscle
Where do the preganglionic parasympathetic neurons for CN IX orginiate and where do they synpase with postganglionic?
Salivatory Nuclei in Tegmentum of Medulla; Synapse in Otic Ganglia in the neck
Loss of general sensation in posterior 1/3 of tongue is a result of damage to CN?
CN IX
Loss of taste perception to posterior 1/3 of tongue results from damage to CN?
CN IX
Ipsilateral loss of gag reflex results from damage to CN?
CN IX
Ipsilateral loss of palatal and uvular reflexes results of damage to CN?
CN IX
Dimished carotid sinue and carotid body receptors results of damage to CN?
CN IX
Dysphagia (difficulty swallowing) results of damage to CN?
CN IX & X
Ipsilateral loss of salivation from loss of preganglionic parasympathetic neurons that innervate the parotid gland results in CN?
CN IX
What are the two motor functions of the Vegus Nerve?
1. Innervates muscles of larynx, pharynx, and soft palate
2. Innervates viscera of thoracic and abdominal as low as left colic flexure (parasympathetic ANS)
What is the longest nerve in the body?
Vegus Nerve
What CN is a part of the General Visceral Afferent System because it innervates visceral structures of thorax and abdomin?
Vegus Nerve
For CN X, where do the UMN and LMN synapse before innervating the larynx, pharynx, and soft palate?
Nucleus Ambiguous in Tegmentum of Medulla
Where do the preganglionic parasympathetic neurons orginate and where do they synapse with post in CN X?
Orginates in Dorsal Motor Nucleus of the Tegmentum of the Medulla; Synapses in numerous ganglia near where the organ to be innervated is...
What six problems can arise from damage of CN X?
1. LMN paralysis to ipsilateral soft palate
2. Dysphagia (difficulty swallowing?
3. LMN paralysis of laryngeal muscles
4. Loss of Gag reflex
5. Loss of palatal uvular reflexes
6. Transient Tachycardia (increased heart rate)
Why is the Spinal Accessory Nerve unique?
Because it has to portions: cranial & cervical (spinal)
Does the corticobulbar UMN synapse with both the cranial and cervical portions of CN XI? If yes, where?
Cranial portion does in the Nucleus Ambiguous in the Tegmentum of Midbrain.
Cervical portion does also in the Spinal Motor Nucleus in Cervical Portion of the Spinal Cord.
Where does the Cervical Portion of CN XI exit the brainstem?
It exists laterally thru the Inferior Olive in the Medulla.
Do the two portions become the spinal accessory nerve before or after it passes thru the Jugular Foramen?
Before it passes the Foramen.
What muscles are innervated by the cranial portion of CN XI and what nerve joins it to innervate those muscles?
Innervates larynx, pharynx, and soft palate. CN XI and CN X join to innervate.
What muscles are innervated by Cervical portion of CN XI
SCM and Trapezius
What area does the Cervical portion of CN XI pass thru to get to the trapezius?
Posterior Triangle in the neck
What CN could be damaged if the patient can not look over there shoulder(lateral rotation)?
LMN paralysis of CN XI
What CN could be damaged if the patients shoulder is downwardly and outwardly rotated?
LMN paralysis of CN XI
Are spinal cord reflexes found in white or grey matter?
Grey matter
Major function of GTO reflex?
Adjust muscle activity
What does the GTO reflex prevent?
With extreme muscle contraction the gto can Prevent tearing of muscles by inhibiting the contraction of the muscle.
How does an Achilles tendon end up tearing if GTO is supposed to prevent that?
Sometimes the GTO doesn't have time to respond.
What 3 primary factors determine muscle tone?
1. Intrinsic characteristics of extrafusal fibers
2. Gravity pulling on skeletal muscles and activating stretch reflexes
3. Gamma bias (supra spinal descending pathways influencing what gamma motor neurons are doing
What is the function of gamma motor neurons?
They alter the sensitivity of the muscle spindle by altering the length of the intrafusal fibers and the tension they exert.
Hypotonia results from what three things?
1. Removing LMN (alpha and gamma)
2. Eliminated the afferent limb
3. Lesions of the cerebellum involved with gamma bias
What type of hypertonia results from hyperreflexia of deep tendon reflexes (dtr)?
Spasticity
What type of hypertonia results from an increase in tone in all muscles although the strength and reflexes are not affected?
Rigidity
Does the cerebellum directly or indirectly project to the ventral spinal horn?
Indirectly
What are the three functions of the cerebellum?
1. Coordinate voluntary muscle activity
2. Coordinate equilibrium activity
3. Influence muscle tone
Refers to the changes that occur in the orgainization of the brain, and in particular changes that occur to the location of specific information processing functions, as a result of the effect of learning and experience.
Neuroplasticity
The pattern of functional and structural changes in responses to environmental physiological or pathological events.
Neuroplasticity
Refers to the brain's ability to change structure and function.
Neuroplasticity
True or False
Brain plasticity may account for the retun of function to speech, language, motor function, and/or sensory function after a stroke.
True
True or False
Neurons make new connections after a period of time after injury due to neuroplasticity.
True
Is phantom limb/pain an example of neuroplasticity?
Yes, it gives a false representation.
Does neuroplasticity affect both sides (injured and uninjured) when setting up new systems?
Yes it does. Bilateral rehabilitation issues meaning setting up new systems on both sides.
What are the four stimulants for neuroplasticity?
1. Loss or modified afferent input to the CNS
2. Damage to the CNS
3. Chemical Stimulations (drugs)
.4. Environmental or training stimulation
There are many theories for neural plasticity, but which one is most important?
Structural changes (anatomical changes)
Stem Cell Activation, Sparing (Remaining Cells Becoming More Active), Redundancy of Systems, Unmasking Secondary Areas, and Structural Changes are all theories for what?
Neuroplasticity
What happens during structural changes in neuroplasticity?
- Increases in synapses
- Modification of synapses
- Increase in dendrites (dendritic sprouting to increase surface area)
- Dendritic and axonal remodeling
How does increasing in dendrites affect neuroplasticity?
The dendric sprouting increases surface area to enhance connection when others have been lost
True or False
Compensation is a form of the neuroplasticity mechanism.
False! A distinction needs to be made between neuroplasticity mechanism at work and the ability of the organism to compensate.
Is neural plasticity only a pathological process?
Nope otherwise we wouldn't be able to learn new tasks like playing the violin (Research supports this)
What influences neural plasticity?
Environmental Stimuli
In regards to neural plasticity, are complex or simple environmental stimuli better?
Complex is better - read out loud instead of to yourself
True or False
Neural Plasticity is not age dependent.
False - It becomes less effective as age increases
Is neural plasticity more effective immediatly following injury or with more time in between?
Most effective immediately following CNS insult (Window of Opportunity)
True or False
Nothing is done in isolation in regards to sides in the CNS.
True
What is the anterior lobe of the cerebellum responsible for?
1. Maintains muscle tone
2. Maintenance of posture
3. Gross voluntary movement (gait)
What happens during structural changes in neuroplasticity?
- Increases in synapses
- Modification of synapses
- Increase in dendrites (dendritic sprouting to increase surface area)
- Dendritic and axonal remodeling
How does increasing in dendrites affect neuroplasticity?
The dendric sprouting increases surface area to enhance connection when others have been lost
True or False
Compensation is a form of the neuroplasticity mechanism.
False! A distinction needs to be made between neuroplasticity mechanism at work and the ability of the organism to compensate.
Is neural plasticity only a pathological process?
Nope otherwise we wouldn't be able to learn new tasks like playing the violin (Research supports this)
What influences neural plasticity?
Environmental Stimuli
In regards to neural plasticity, are complex or simple environmental stimuli better?
Complex is better - read out loud instead of to yourself
True or False
Neural Plasticity is not age dependent.
False - It becomes less effective as age increases
Is neural plasticity more effective immediatly following injury or with more time in between?
Most effective immediately following CNS insult (Window of Opportunity)
True or False
Nothing is done in isolation in regards to sides in the CNS.
True
What is the anterior lobe of the cerebellum responsible for?
1. Maintains muscle tone
2. Maintenance of posture
3. Gross voluntary movement (gait)
What is the posterior lobe of the cerebellum responsible for?
Coordination of fine voluntary movement
What is the flocculonodular lobe of the cerebellum responsible for?
Maintenance of equilibrium
A classical cerebellar symptom is?
General Ataxia
Abnormality in muscular coordination leading to abnormality of voluntary movement.
General Ataxia
What are signs of ataxia in the anterior lobe of the cerebellum?
- Muscles contract weakly and irrecgulary
- Unsteady or drunken gait
- Feet spaced far apart to stablize
- Lean or lurch to affected side
What are signs of ataxia in the posterior lobe of the cerebellum?
-Intentional tremor/terminal tremor
- Dysmetria (inability to stop a muscle movement at a desired point)
- Dyssynergia (voluntary movements are jerky and tremor like
- Dysdiadokinesia(inability to perform rapid & alternating movements
- dysarthria (slurred or hesitant type of speech)
Is hypotonia a possible sign of damage to the anterior lobe of the cerebellum?
Yes, influences gamma bias
Is nystagmus a possible sign of damage to the flocculonodular lobe of the cerebellum?
Yes
Is basal ganglia a part of the pyramidal or extrapyramidal system?
Extrapyramidal System
Where is the basal ganglia found?
Deep seated within white matter of cerebral hemispheres.
What is the posterior lobe of the cerebellum responsible for?
Coordination of fine voluntary movement
What is the flocculonodular lobe of the cerebellum responsible for?
Maintenance of equilibrium
A classical cerebellar symptom is?
General Ataxia
Abnormality in muscular coordination leading to abnormality of voluntary movement.
General Ataxia
What are signs of ataxia in the anterior lobe of the cerebellum?
- Muscles contract weakly and irrecgulary
- Unsteady or drunken gait
- Feet spaced far apart to stablize
- Lean or lurch to affected side
What are signs of ataxia in the posterior lobe of the cerebellum?
-Intentional tremor/terminal tremor
- Dysmetria (inability to stop a muscle movement at a desired point)
- Dyssynergia (voluntary movements are jerky and tremor like
- Dysdiadokinesia(inability to perform rapid & alternating movements
- dysarthria (slurred or hesitant type of speech)
Is hypotonia a possible sign of damage to the anterior lobe of the cerebellum?
Yes, influences gamma bias
Is nystagmus a possible sign of damage to the flocculonodular lobe of the cerebellum?
Yes
Is basal ganglia a part of the pyramidal or extrapyramidal system?
Extrapyramidal System
Where is the basal ganglia found?
Deep seated within white matter of cerebral hemispheres.
What are the three basal ganglias?
1. Caudate Nucleus
2. Putamen
3. Globus Pallidus
What forms the extrapyramidal system?
3 basal ganglia, red nucleus, substantia nigra, and subthalamic nucleus
Does the basal ganglia have a direct or indirect relationship with LMNs?
Indirect
How does the basal ganglia influence the reticulospinal tract?
The basal ganglia sends info to the reticular formation which goes to the ventral horms
How does the basal ganglia influence the corticospinal tract?
Basal ganglial sends info to pre-central gyrus to influence UMN
How does the basal ganglia influence the nigroreticular tract?
Basal ganglia sends info to substantia nigra in the midbrain which goes to reticular formation and ends up tin the reticulospinal tract
How does the basal ganglia influence the thalamocortical tract?
Basal ganglia sends info to thalamus which then sends info to cortex thru thalamocortical tract.
Can the pyramidal and extrapyramidal systems work alone?
Nope They are intimately integrated
Does the basal ganglia assist in inhibiting co-contraction of antagonistic muscles of the limbs?
Yes
Does the basal ganglia assist in adjusting body position during movement for a specific task?
Yes
Does the basal ganglia work on a subconcious or reflex level?
Yes it does
Reducttion in the initian, implementation,and facilitation of execution of movement.
Hypokinesia
What characteristics are common with basal ganglia damage?
- Hypokinesia
- Symptoms associated with Parkinson's Disease
What are two descriptions of hypokinesia?
- Hypertonia
- Rigidity
Define cogwheel rigidity
Rigidity with increased jerky resistance for PROM (increase in muscle tone)
Define Plastic Rigidity
Rigidity with increased resistance to PROM that is constant, continuous and smooth (lead pipe)
What are some symptons of Parkinson's Disease?
1. Concious movement may be suppressed with hypokinesia
2. Abnormal postures assumed
3. Arm swing during gait is absent.
4. DTR are usually normally
5. Facial expression may be masked.
What's happening with the pathology of Parkinson's Disease?
- Degeneration of substantia nigra of midbrain
- Decreased amounts of neurons leads to a dopamine-depleted basal ganglia(decreased dopamine=decreased inhibition)
- Disinhibition (Basal ganglia cannot be inhibited & will do things in an uncontrolled manner
What is the disinhibition phenomenon?
Involuntary movement because basal ganglia is no longer inhibiting the movement
What are four involuntary movements associated with basal ganglia damage?
1. Static Tremor / Alternating Tremor
2. Athetosis
3. Chorea
4. Ballism
What is the hallmark of basal ganglia dysfunction?
Static tremor
Pin rolling (alternating tremor) is and is located in what nucleus?
Involuntary movement and is supressed when intentional skilled muscle activity; Caudate Nucleus
Involuntary movement characterized by slow, writhing, worm-like movements of the fingers. What part of basal ganglia involved?
Athetosis; Putamen
Sudden, involuntary, jerky movements along with grimacing or twitching of facial muscles and faulty vocalization. What basal ganglia involved?
Chorea; Caudate Nucleus
Involuntary movements of an entire limb; begins proximally and proceeds distally like a wave; may involve one or more extremity of the same side.
Ballism
Is ballism indicative of a subthalamic stroke?
Yes
What are the excitatory neurotransmitters and neuromodulators?
- ACh
- Glutamate
- Aspartate
Inhibitory neurotransmitters and neuromodulators for the basal ganglia?
- GABA
- Dopamine
- Glycine