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16 Cards in this Set

  • Front
  • Back
Signs of Chronic renal failure [CRF]
1. HTN
2. Volume overload / pulmonary oedema
3. Pericarditis
4. Bleeding
5. Encephalopathy
6. Anaemia
7. Hyperkalaemia
8. Metabolic acidosis
9. Peripheral neuropathy
Treatment of acute bleeding in CRF
1. DDAVP [first line] stimulates vWF release
2. Cryoprecipitate [ I/II/VIII/XIII/vWF ]
3. PRBC transfusion
Indications for Emergent Dialysis in CRF ; "AEIOU"
Acidosis [ metabolic acidosis]
Electrolyte disturbance
1. hyperkalaemia
2. Hypercalcaemia
Ingestions [ Toxic ingestions ]
Overload [ pulmonary oedema / severe HTN ]
Uraemia
1. Encephalopathy
2. Pericarditis
3. Severe Nausea and vomiting ++
Complications of Haemodialysis ?
1. Hypotension [ 20-30% ]
2. Bleeding
3. Dialysis Disequilibrium Syndrome
4. Fistula-specific problems
5. Vascular access infection
Causes of Haemodialysis hypotension? [7]
1. Fluid shifts with spontaneous resolve**

[common]
2. AMI
3. Tamponade
4. Bleeding
5. Infection {Sepsis}
6. Anaphylaxis
7. Air embolism

Causes and sources of Haemodialysis

bleeding?

1. Platelet dysfunction
2. Transient thrombocytopenia
3. Anticoagulation

Typically puncture site bleeding

{most common}

Treatment of bleeding associated with haemodialysis?
1. DDAVP ** [ 0.3ug/kg IV ]
2. Cryoprecipitate
3. PRBC transfusion
4. Protamine [ heparin reversal ] 10-20mg
List fistula-specific problems associated with Haemodialysis
1. Puncture site bleeding **
2. True aneurysms [rare]
3. Pseudoaneurysm
4. Thrombosis
5. High output failure [ Branham sign ]
6. Infection [ Gram positive > G - ]
Salient features of peritoneal dialysis-related peritonitis
1. Fever + abdominal pain
2. Cloudy PD fluid
3. PD fluid :
a. > 100 WCC/mm
b. >50% Neutrophils
c. + Gram stain

4. Gram positive {Strep/Staph} > G- > anaerobes > fungi
5. Mx with intraperitoneal Antibiotics
a. Vancomycin
b. OR cephalosporin 3rd Gen.
Mnemonic for Causes Chronic Renal Failure [CRF]: "He Gets Very Tired"
Hereditary PKD
Glomerular Disease
1. Primary
2. Secondary [Diabetes** / SLE / Amyloid]
Vascular Disease
1. HTN**
2. Atheroma
3. Vasculitis
Tubulointerstitial Disease
1. Reflux / pyelonephritis
2. Nephrocalcinosis
3. Interstitial nephritis
4. Obstruction
Key questions to ask the CAPD patient
1. Cause of ESRF
2. Baseline values
a. weight
b. vital signs
c. laboratory values
3. Peritoneal dialysis parameters
a. concentration
b. exchanges per day
4. Recent complications of PD
5. Uraemia symptoms
6. Still urine producing?
Key questions to ask the haemodialysis

patient

1. Cause of ESRF
2. Baseline values
a. Dry weight
b. vital signs
c. laboratory values
3. Dialysis schedule
4. Recent comlpications of HD
5. Does patient make dry weight post HD
6. Intradialysis hypotension?
7. Currently functioning vascular access
8. Uraemia symptoms
9. Still producing urine?
Causes of predialytic, intradialytic and post

dialytic hypotension?

Predialytic
1. Preexisting hypovolaemia [starts below dry weight ]
a. GI bleeding
b. Sepsis
c. D + V
d. decreased salt/water intake
2. intradialytic hypotension
a. leaks from blood tubing / haemodialyser
3. Post Dialytic Hypotension
a. Excessive ultrafiltration
b. cardiac disease
c. pericardial disease
The main initial areas for focus with the Renal HD patient presenting with hypotension.
1. Volume status
2. Cardiac function impairment
3. Pericardial disease
4. Infection
5. GI bleeding
What is "Dialysis disequilibrium" Syndrome?
1. Occurs at the end of dialysis
2. Cerebral oedema from osmolar imbalance b/w brain and blood
2. Characterised by:
a. Nausea
b. Vomiting
c. Hypertension
3. Can progress to :
a. Seizures
b. coma
c. death
4. Treatment:
a. cease dialysis
b. IV mannitol
Why is it important to ask the ESRF patient about their native kidneys?
Retained native kidneys can be a continuing source of:


1. Hypertension
2. Infection
3. Calculi