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8 Cards in this Set

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Regarding the RIFLE classification of ARF, which is incorrect:
1. The RISK stage has a U/O < 0.5ml/kg/hr for 6 hrs
2. The INJURY stage has a Cr increase of >1.5x baseline
3. The FAILURE stage has a increase in Cr of > 3x baseline
4. The LOSS stage has complete loss of kidney function longer than 4 wks or persistent ARF
5. END stage renal disease is diagnosed when it is present for longer than 3 mths
2 is wrong CAM 462
Regarding causes of acute kidney injury, which is incorrect:
1. ATN is the most common pathological process causing ARF
2. hypovol may be marked by a rise in Urea without a rise in Cr
3. NSAIDS may cause cytotoxic ATN even in healthy people
4. ATN causes 1-2 wks of reduced GFR before potential recovery
5. hydronephrosis may occur without obstruction in pregnancy, VUR, or in diabetes insipidus
3 is wrong - they don't impair renal function in healthy ppl but can reduce GFR in elderly with atherosclerotic disease, in CRF, or in ppl using diuretics and CCBs
Causes of cytotoxic ATN include (which incorrect):
1. radiocontrast
2. NSAIDS
3. Amphotericin
4. Aciclovir
5. Cyclosporin
6. methanol
7. Hb
8. myoglobin
9. myeloma proteins
10.uric acid
6 is wrong (as far as I can find); ethylene glycol causes ATN
CAM 464
regarding rhabdomyolysis, which is incorrect:
1. in crush injuries, U/O should be maintained at more than 100ml/hr
2. mannitol and Na bicarb have been shown to be effective in preventing ATN
3. hypovol may be caused by fluid sequestration
4. compartment syndrome may result
5. urine dipstick findings may be normal
6. muscle pain is absent in 50%
1 is wrong - 200-300ml/hr, in rhabdo due to noncrush causes more than 100ml/hr is correct
regarding clinical features of acute kidney injury, which is incorrect:
1. thrombotic thrombocytopenic purpura usually presents with severe neurological involvement
2. renal size may be normal or increased in CRF due to DM, PCKD, or amyloidosis
3. HUS usually presents with severe neurological involvement
4. Complete anuria may be due to severe ATN, rapidly progressive GN, vascular lesions or total obstruction.
3 is wrong - paeds condition, causes ARF with absent or min neurological abn
Electrolyte abn in acute kidney injury, which direction do the following move in?
1. Ca
2. PO4
3. Uric acid
4. Mg
1. Ca reduced.
Others increased.
regarding K in acute kidney injury, which is incorrect:
1. K concentration may be low in acute kidney injury
2. the first ECG changes in hyperK are shortening of PR and QT intervals
3. the Sine wave appears with K of 8-9
4. Sinoventricular and junctional rhythms may occur
3 is wrong - usual when K more than 10
Regarding management of acute kidney injury, which is incorrect:
1. No therapeutic intervention has hastened the recovery of renal function in established ATN
2. renal replacement therapy may be indicated in severe metabolic acidosis with pH of less than 7.1, pulmonary oedema not responding to diuretics, uremic sydrome
3. a Na concentration of less than 100, or more than 160 is indication for dialysis or haemofiltration
4. AKI due to hyperCa should no longer be treated with Lasix
4 is wrong - frusemide is still used.