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16 Cards in this Set
- Front
- Back
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What is the best management for all patients with Wilm's tumor?
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-Immediate surgical resection
-F/u ultiagent chemotherapy |
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What WT patients should recieve radiation therapy?
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Those with advanced tumor
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What is the first red flag that should make you think wilm's tumor?
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Abdominal mass
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What 3 findings are the typical presentation of wilm's tumor?
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-Abdominal pain
-Abdominal mass -Hypertension |
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What IS wilm's tumor?
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The most common primary renal malignancy in childhood
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In what sex is WT more common in the world? US? What race?
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World - equal
US - girls Blacks > whites |
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What 4 congenital anomalies are WT's often associated with?
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-Aniridia
-Hemihypertrophy -Horseshoe kidney -Hypospadias |
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What Ch' deletion is associated with 30% of WT's?
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Ch 11
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Median age at diagnosis of a wilm's tumor:
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3
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What are 6 symptoms often seen in WT patients?
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-Abdominal/flank pain and mass
-Hypertension -Hematuria -Anemia -Fever |
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What is the major tumor to differentiate a wilm's tumor from?
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Neuroblastoma
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How do patients with WT ocmpare to those with neuroblastoma?
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WT older
WT less sick |
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What lab tests help point toward neuroblastoma?
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Urine HVA and VMA
Enolase Ferritin LDH |
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What % of WT patients have bilateral masses and metastases at diagnosis?
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5% bilateral
15% metastases |
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What is the overall cure rate for WT with surgical excision and f/u chemo?
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>85%
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Where do neuroblastomas tend to metasesize in children, leading to what symptoms?
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To the periorbital regions - develop periorbital ecchymoses and proptosis
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