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10 Cards in this Set
- Front
- Back
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Haemophilus influenzae
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small, fastidious, gram negative
COCCOBACILLUS normal nasopharyngeal flora some strains have polysaccarhide capsule needs CHOCOLATE AGAR |
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HI diseases (b strains)
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meningitis
cellulitis pneumonia arthritis epiglottitis |
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HI pathogenesis
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colonization of nasopharyngeal epithelium
* fimbrie and iGa protease penetration of epithelial cells antiphagocytic capsule |
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HI dx
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gram stain of CSF
culture from sterile site |
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HI tx
(peak incidence in 6mo-2yr group) **incidence DRASTICALLY decreases with vaccination** |
AB- cefotaxime, ceftriaxone, and vancomycin
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HI PRevention
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prophylatic AB for close contacts
vaccine = purified capsular polysaccaride w/ is conjugated to protein |
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HI non - invasive disease
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acapsular "non-typeable strain" or non B capsular strains
Otitis Media (s. pneumoniae and moraxella catarrhalis) Sinusitis Chronic bronchitis and pneumonia *COPD |
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Acute Otitis Media caused by.
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s. pneumococcus
*capsule non-typeable h. influenzae *lipoprotein, LPS structure moraxella catarrhalis |
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AOM details
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1. 6 to 24 month most affected
2. clinical observation of ear 3. analgesics, watch and wait, and AB = amoxicillin, amoxicillin +clavulanate, trimethoprim + sulfamethoxazole, cephalosporins |
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OM w/effusion
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presence of fluid in middle ear w/o signs of acute infection
insert tubes AB not in routine management |
