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3 Cards in this Set
- Front
- Back
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What is the main severe side effect of the imidazoles?
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hepatotixicity
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What is the mechanism of action of griseofulvin and where does it accumulate?
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interacts with microtubules to disrupt mitotic spindles, thereby inhibiting mitosis
accumulates in keratin, making skin and nail beds unsuitable for fungal growth |
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What is the mechanism of action of the allylamines?
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terbinafine and butenafine (treat tinea infections)
inhibit squalene epoxidase |
