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30 Cards in this Set
- Front
- Back
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50 yo man complains of diarrhea. On physical exam, face is plethoric and heart murmer is detected. Diagnosis?
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Carcinoid syndrome
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Woman of short stature presents w/ shortened 4th and 5th metacarpals -- what endocrine disorder?
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Albright's hereditary osteodystrophy, or pseduohypoparathyroidism
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Double vision, gynecomastia, headaches -- diagnosis?
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Prolactinoma
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Pt's MRI shows filling of sella turcica w/ CSF -- most likely clinical presentation?
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NOrmal -- residual pituitary tissue functional and can compensate (empty sella syndrome).
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Hormones released by pituitary gland?
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FSH, LH, ACTH, TSH, ProlactIn, GH (FLAT PIG)
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Which cells in pituitary are basophils?
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FSH, LH, ACTH, TSH (B-FLAT)
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Which cells in pituitary are acidophils?
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ProlactIn, GH
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alpha-subunit common to which which hormones?
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FSH, LH, TSH, hCG (FLAT Pituitary hormones e/c for ACTH, and hCG)
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Where are delta cells of pancreas most numerous?
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In the tail of the pancreas
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What is Chvostek's sign?
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Tap facial nerve --> contraction of facial muscles. Sign of tetany seen in hypocalcemia.
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What is Trousseau's sign?
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Occlusion of brachial artery w/ BP cuff -> carpal spasm. Test to screen for hypoparathyroidism.
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What are the steroid/thyroid hormones?
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Progesterone, Estrogen, Testosterone, Cortisol, Aldosterone, and Thyroxine & T3 (PET CAT)
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skeletal muscle and adipose tissue take up glucose via which transporter?
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GLUT-4.
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Brain and RBCs take up glucose via which transporter?
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GLUT-1.
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Which glucose transporter found in renal tubular cells, SI epithelial cells, and liver & pancreatic cells?
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GLUT-2
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Increased cortisol due to pituitary adenoma?
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Cushing's Disease
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Increased cortisol due to primary adrenal hyperplasia?
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Cushing's Syndrome
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Treatment for pheochromocytoma?
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Alpha-antagonist, especially phenoxybenzamine, a non-selective irreversible alpha-blocker.
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Sx: Pressure, Pain, Perspiration, Palpitations (tachycardia), and Pallor. Dx?
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Pheochromocytoma
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Pancreas, Parathyroid, and Pituitary tumors -- what syndrome?
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MEN I
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What syndrome presents with MCT, pheo, and parathyroid tumor?
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MEN II (Sipple's syndrome). 2 P's
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What syndrome presents with MCT, pheo, and neuromas?
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MEN III (formerly MEN IIb). 1P.
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Tx for Graves disease?
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Propylthiouracil. Inhibits production of thyroid hormone as well as peripheral conversion of T4 to T3.
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Tx for acromegaly?
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Octreotide. Somatostatin analog that inhibits GH.
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Causes of hypercalcemia?
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Calcium ingestion, Hyperparathyroid, Hyperthyroid, Iatrogenic (thiazides), Multiple myeloma, Paget's disease, Addison's disease, Neoplasms, Z-E syndrome, Excess vit D, Excess vit A, Sarcoidosis ("CHIMPANZEES")
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T1DM is associated with which HLAs?
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HLA-DR3 and 4
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What tetracycline antibiotic can also be used to treat hyponatremia due to SIADH?
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Demeclocycline
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Recurrent diarrhea, cutaneous flushing, asthmatic wheezing, and right-sided valvular disease. What disease?
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Carcinoid syndrome
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Z-E syndrome associated with which MEN?
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MEN I
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Tx for carcinoid syndrome?
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Octreotide. Somatostatin analog that decreases secretory activity of carcinoid.
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