4.14 C) Acid Base Disorders Metabolic Alkalosis

Front 1

Which Common disorders of metabolic alkalosis are often confused with Gitelman's Syndrome?

Back 1

1. Diuretic abuse
2. laxative abuse
3. Surreptitious vomiting

Front 2

Gitelman's Syndrome is due to a defect in

sodium reabsorption in in which part of the

renal tubule?

Back 2

Sodium-chloride cotransporter in DCT - Distal Convoluted Tubule.

[segment of tubule where Thiazide diuretics work ]

Front 3

Bartter's Syndrome is due to a defect in

sodium reabsorption in which part of the renal tubule?

Back 3

Ascending Limb of LOH

[ Segment of tubule where loop diuretics work ]

Front 4

Differences between Bartter's and Gitelman's Syndrome?

Back 4

Bartter's :

1. hypercalciuria
2. Not in adults

Front 5

Metabolic alkalosis compensation formula?

Back 5

Expected PCO2 should be 40-55
last 2 digits of pH = actual PCO2

< 40 = additional respiratory alkalosis
> 55 = additional respiratory acidosis

Front 6

Treatment of Metabolic Alkalosis ?

Back 6

"Saline responsive" :
TREAT UNDERLYING CAUSE, as well as:
1. NaCl replacement
2. K replacement [ and Mg2+]

"Saline resistant":
TREAT UNDERLYING CAUSE, as well as:
1. Potassium replacement
2. +/- Dialysis