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7 Cards in this Set

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In regards to An increased serum osmolality and the associated Clinical Symptoms and signs, which is incorrect?
A. > 430 = Seizures and coma
B. > 350 = excessive thirst
C. > 420 =focal Neurological defect.
D. > 400 = weakness and lethargy.
D.
> 400 = ataxia and tremor
> 375 = weakness and lethargy
What are the 3 main categories for the causes of Hypernatraemia?
1. Inadequate water intake
2. Excessive sodium
3. Loss of Water >> Sodium
What are the main reasons behind inadequate water intake in hypernatraemia?
1. Unable to obtain
2. Dysphagia
3. Impaired thirst

** typical of elderly / disabled - Inadequate intake
What are the main causes of excessive sodium intake?
1. Iatrogenic ( hypertonic saline ; NaHCO3 )
2. Accidental salt ingestion
3. Excess mineralocorticoid / Glucocorticoid (Cushings)
What are the main causes of Loss of water >> sodium, causing hypernatraemia?
1. GIT ( vomiting and diarrhoea)
2. Renal ( Diabetes insipidus ; osmotic diuresis -DKA)
3. Skin ( sweating in heat stroke and burns)
How fast should the sodium be lowered and corrected for hypernatraemia?
Slowly, over 24-48 hours

0.5 - 1.0 mmol / L / Hr
Which of the following is incorrect regarding the causes of hypernatraemia?
A. The Elderly usually have an inadequate water intake as their aetiology. (unable to obtain / dysphagia)
B. It can be caused by Iatrogenic reasons - eg. drugs ( antibiotics and lithium)
C. It is caused by reduced mineralocorticoid / glucocorticoids.
D. Vomiting and diarrhoea can lead to hypernatraemia.
C. Excess mineralocorticoids / glucocorticoids ( Cushings)