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9 Cards in this Set

  • Front
  • Back

what is fever

a high body temperature

what does fever cause

an increase in body metabolism


accelerated defenses


inhibition of some viruses and bacteria


causes liver and spleen to sequester iron and zinc (needed by microorganisms)

what constitutes a fever

maintained body temperature above 34C or 99F

what is a pyrogen

any material that causes the hypothalamus to raise body temperature

what can be a pyrogen

circulating pathogens, toxins, or antibody complexes

what is our endogenous pyrogen

interleukin-1 (IL-1)

how is interleuikin-1 triggered

by bacterial pathogens


it is a pyrogen released by active macrophages

what are interleuikins

a group of immunoregulating chemical messengers release by T(h) macrophages and other cells

what are general responses of interleukins

increasing T cell sensitivity to antigens


stimulating B cells


enhancing non-specific defenses


+a subgroup moderates the immune response