Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
13 Cards in this Set
- Front
- Back
|
What are the tests for the extrinsic and intrinsic pathways of the clotting cascade?
|
extrinsic: PT
intrinsic: PTT |
|
|
Any vWF deficiency will also cause a deficiency in what?
|
factor VIII functional deficiency
|
|
|
Name the causes of DIC.
|
Sepsis, Trauma, Obstectric complications, acute Pancreatitis, Malignancy, Nephrotic syndrome, Transfusion
STOP Making New Thrombi |
|
|
Name the signs and symptoms of TTP.
|
1. thrombocytopenia
2. schidotcytes 3. evidence of hemolysis low Hb, high reticulocyte count, polychromasis on blood smear, high LDH 4. fever 5. ischemic organ damage |
|
|
Name the drugs that can cause hemolysis in G6PD deficiency.
|
INH, sulfonamides, primaquine, Aspirin, ibuprofen, nitrofuratoin, dapsone, naptholene
|
|
|
Sickling of RBCs in sickle cell anemia is promoted when what occurs?
|
whenever less then optimal oxygenation of the Hb occurs: hypoxia, acidosis, and dehydration
|
|
|
Name some causes for warm agglutinin disease.
|
drugs
malignancies SLE chronic anemia |
|
|
What are these clinical findings associated with?
leukopenia, hypersegmented neutrophils, thrombocytopenia |
megaloblastic anemia
|
|
|
What are Howell-Jolly bodies and what do they indicate?
|
visible nuclear fragments within RBCs; appear as basophilic granules
indicative that RBCs are leaving bone marrow while still immature |
|
|
What are some causes of neutropenia?
|
1. decreased production: bone marrow dz, chemo, HIV infection, other drugs, Vit b12 or folate deficiency
2. increased destruction: Felty's syndrome |
|
|
What are 2 causes of monocytosis?
|
infectious mononucleosis
granulomatous disease |
|
|
What leukemia is associated with low laukocyte alkaline phosphatases?
|
CML
|
|
|
What leukemia is associated with smudge cells?
|
CLL
|
