Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
21 Cards in this Set
- Front
- Back
|
What are the 4 main areas of clinical impact of endometriosis?
|
-Infertility
-Dysmenorrhea -Dysparuenia -Chronic pelvic pain |
|
|
What IS endometriosis basically?
|
Endometrial tissue in sites outside the uterus
|
|
|
What are the 4 most common sites of endometriosis?
|
-Ovaries
-Uterosacral ligaments -Rectovaginal septum -Pelvic peritoneum |
|
|
What is an Endometrioma?
|
An island of endometrium in an ovary that is large enough to call it a tumor
|
|
|
What is Adenomyosis?
|
Endometrial tissue in the muscular wall of the uterus
|
|
|
How are Endometriosis and Adenomyosis different?
|
Clinical course - endometriosis gets progressively worse with increasingly diverse symptoms; Adenomyosis remains in the uterus
|
|
|
What are the 2 main presenting sx of Adenomyosis?
|
-Dysmenorrhia
-Menorrhagia |
|
|
What is required to make a definitive diagnosis of Endometriosis?
|
HISTOLOGY
|
|
|
What is required to confirm the diagnosis?
|
Laparotomy and/or endoscopy
|
|
|
What is the prev of endomtrs in
-general population -Infertile women |
General: 1-2%
Infertile: 20-30% |
|
|
What is the triad of microscopic findings needed for diagnosis of endometriosis?
|
-Endometrial stroma
-Glands -Hemosiderin laden macrophages |
|
|
What are 5 classic symptoms of endometriosis?
|
PAIDD
-Pelvic pain -Abnormal bleeding -Infertility -Dysmenorrhea -Deep thrust dyspareunia |
|
|
What are 3 possible management approaches to endometriosis?
|
-Observe
-Medicine -Surgery |
|
|
Who might you just observe?
|
-Premenopausal woman who will soon undergo atrophy anyway
-Someone who wants to get pregnant and is asymptomatic |
|
|
What are 2 'pseudo' states that drugs intend to induce in a patient with endometriosis?
|
-Pseudopregnancy
-Pseudomenopause |
|
|
What drugs induce a pseudopregnancy state?
|
OCPs
|
|
|
What drugs induce a pseudomenopause state?
|
Danazol
|
|
|
What is Danazol?
|
A 17-a-ethinyl testosterone derivative that suppresses LH and FSH surges
|
|
|
What are 2 side effects of Danazol?
|
-Vasomotor symptoms
-Hypoestrogenic symptoms |
|
|
What other drug suppresses LH/FSH levels?
|
GnRH agonists - continuous
|
|
|
What are the 3 GnRH agonists?
|
-Leuprolide
-Nafarelin -Goserelin |
