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31 Cards in this Set

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a healthy 19 yo G1P0 at 29 weeks gestation complains of intermittent abdominal pain but denies LOF, has an unremarkable antenatal history
The tocometer shows UCTx's every 3 minutes
this is a case of preterm labor
she is contracting regularly and showing crvical change before 37 weeks
What is the next step in mgmt for this preterm labor?
do tocolysis and get some steroids on board
Why use antibiotics?
they prolong latency and are propylactic for intra-amniotic infection
How do you test vaginal fluid to confirm a rupture of membranes?
fetal fibronectin

also ferning and nitrazaine
What is the cervical change in a nulliparous woman that would indicate labor?
2 cm dilation
80% effaced
What is the big use of fetal fibronectin?
it's good for predicting whether or not a patient will deliver within a week
If the fetal fibronectin is negative, then
you worr ymuch much less about them delivering early. it would be highly unlikely
if the FFN is positive, then the likelihood of them delivering is quite high
This would favor immediate tocolysis
What is the time window for giving steroids again?
24 to 34 weeks
What are two contraindications to tocolysis for preterm labor?
severe pre-eclampsia

and

intra-amniotic infections

With these two conditions you want them to just go normall
What are some of the possible causes of preterm labor?
UTI
cervicitis
bacterial vaginosis
trauma
abruption
hydramnios
multiple gestation
What would this look like if this girl was less than 20 weeks pregnant?
it would look more like an inevitable abortion
What is fibronectin exactly?
it's some sort of intra-amniotic basement membrane protein
What is considered a "short cervix?"
less than 25 mm
You can also see...
cervical funneling where they have impingement of the amniotic cavity
What % of pregnancies are complicated by preterm labor?
11%
What are some risk factors for PTL>?
PPROM
Multiple gestation
hydramnios
previous preterm labor
uterine anomalies
hx of leep or cone knife biopsies
cocaine
African American race
trauma
pyelonephritis
so remember some of these weird ones
UTI
African American
uterine anomalies
what are some features of the workup for PTL?
H&P
sterile spec exam to look for pooling
digital cervical exam to look for change
CBC
urine drug screen for cocaine
u/A to look for UTI
GC/CT cultures
So as soon as you establish a PTL dx you then want to be asking why
in this cse it could have been due to prior hx
What are some options for tocolytics?
MgSO4
Nifedipine- CCB
Terbutaline- but this should be down the list
Indocin- Dr. Jackson thinks it might be the best one
What are some side effects of the magnesium?
you can toxically high levels where you see decreased DTRs, respiratory depression, pulm edema etc.
Nifedipine has very similar side effect profile
yep
remember that a single pregnancy can only get ONE DOSE of steroids
y
What STI is most strongly associated with PTL?
gonorrhea cervicitis
is chlamydia associated with PTL?
not really
do you give tocolytics with suspected abruption?
no no no

this greatly increases their chances of postpartum hemorrhage
Even SUSPECTEd abruption is basically
a contraindication to tocolytics
because what is the main problem giving PPH anyway
uterine atony- so if you give tocolytics then the uterus is not going to contract down well
o Dyspnea in a women with preterm labor is often from B agonist therapy giving pulm edema
o Goal in treating PTL: ID the cause, give steroids, and tocolysis
o RDS is the most common cause of mortality in preemies
o B agonist therpy- all sorts of SNS-driven side effects
o Negative ffn assays virtually guarantee no delivery within the week
o TVUS can indicate a shortened cervix less than 25 mm
yep