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216 Cards in this Set

  • Front
  • Back

History of a child with a rash...

-onset, duration


-skin symptoms: itch, hurt


-systemic symptoms: fever, malaise, pertinent ROS


-exposures: travel, outdoor activities, animals, sick contact, new meds


-pertinent PMH: immune status, chronic illness, valvular heart disease

what are you looking for with a rash?

-primary lesions


-secondary lesions


-color


-pattern


-distribution

flat, less than 1 cm

macule

raised less than 1 cm

papule

flat greater than 1 cm

patch

raised greater than 1 cm

plaque

deep raised lesion greater than 1 cm

nodule

blister less than 1 cm, clear fluid

vesicle

filled with pus less than 1 cm

pustule

fluid filled greater than 1 cm

cyst

secondary


part of epidermis is missing, shiny, oozing

erosion

secondary


deep hole with all epidermis gone

ulceration

secondary


yellowish dry serum +/- itfection

crusting

secondary


flaky bits of epidermis separating

scaling

secondary


punctate to linear scratch marks

excoriations

secondary


linear cracks

fissures

skin exam: color

red, yellow, brown, black, tan or blue

skin exam: pattern

discrete, linear, grouped, annular

skin exam: distribution

generalized or localized, specific areas

what are the differential diagnoses for rashes?

-blistering disorders


-papular disorders


-erythemas


-papulosquamos conditions


-eczematous disorders


-vascular lesions


-pigmentation problems

fever and palpable purpura is _____ until proven otherwise.

meningococcemia

palpable purpura is ____; there is no good ___

vasculitis, vasculitis

the ____ the purpuric lesion the worse the disease

larger

widespread bullae represent ___ until proven otherwise

TEN

all bullous eruptions should be assessed for _____ ___.

nikolsky sign

____ tests take time, do not wait to start empiric therapy

lab tests

most common skin disorders in peds are caused by ____ infections

bacterial infections

upper arm bumps are called?

keratosis pilaris

what are triggers in atopic dermatitis?

-saliva, wet bibs, food spills


-URI


-soaps, detergents


-bacterial skin infections (impetigo, folliculitis)


-vaccinations


-smoke, fragrences

toxic sock syndrome also known as ___ ___ ___ is eczema on the feet from sweaty, stinky feet.

juvenile plantar dermatitis

how do you treat juvenile plantar dermatits (toxic sock syndrome)

frequent sock and shoe changes and vasaline before putting on socks

Atopic Dermatits- Therapeutic Principles


hydrate and

lubricate

Atopic Dermatits- Therapeutic Principles


____ emollients; especially after bath

unscented

Atopic Dermatits- Therapeutic Principles


avoid irritants such as:

-fragrances


-cleaning agents


-wool


-heat


-detergents

Atopic Dermatits- Therapeutic Principles


control inflammation with

-topical steroids


-immunomodulators

Atopic Dermatits- Therapeutic Principles


address the itch with

-cool compresses


-antihistamines

patient/parent education on atopic derm

-educate parents to avoid triggers


-help identify a food allergen if present


-investigate IgE allergens and try to determine relevance

the opportune time to introduce solids is?

4-6 months

82% of ___ allergic children have AD

peanut

babies who develop severe AD in the first ____ months of life are at risk for food allergy like milk, egg, peanut

3 months

peanut sensitization is independently associated with

-soy formula


-household peanut consumption


-use of peanut oils in skin prep

early exposure to furry pets might have a ____ effect on AD

protective

high dust mite counts have a ____ effect on AD

protective

how often should barriers be applied in AD

3-4 times per day

always lubricate immediately after

a bath

after swimming...

shower and lubricate immediately

intermittent ____ baths and inranasal ____ decrease severity of eczema

-bleach baths


-mupirocin

about how much bleach should go into a full tub?

about 1/2 cup

newer generation topical steroids focus on increased _____ and _____ receptor affinity

-lipophilicity


-glucocorticoid (inflammation control only)

what are the safe topical steroids in kids?

-mometasone


-fluticasone


-alclometasone


-fluocinolone


-desonide


-prenicarbate

____ is only approved for 17 years and up because it has shown adrenal insufficiency and growth deficiency

triamcelone

which two topicals have the best therapeutic index?

-mometasone


-fluticasone

what are the two macrolactam immunomodulators?

-tacrolimus


-pimecrolimus

macrolactam immunomodulators interfere with phosphate activity of the calcineurin/calmodulin complex leading to a potent ____ ____ effect without immunosuppresion.

anti-inflammatory

prenatal and postnatal use of _____ reduce the risk of AD for the child

probiotic

_____ ___ ____ is a delayed type hypersensitivity to a variety of antigens

allergic contact dermatitis

what are the most common plants in contact derm?

-poison ivy


-poison sumac


-poison oak

what are the most common non plant sources of contact derm?

-nickel


-neomycin (neosporin)


-rubber

the rash of contact derm is papular to vesicular, intensely _____ and a _____ distribution

-puritic


-bizarre distribution

plant dermatitis is often ____ with lesions in different stages

linear

how do you treat contact derm?

-topical or oral steroids

poison ivy, oak and sumac can occur at any age. there is cross reactions with japanese lacquer tree, ginko, raw cashew sheels, mango skin. ____ is not useful

hyposensitization

most insect bites produce ___ ____.

papular urticaria

atopic children can have arthopod bite _____ reaction.

hypersensitivity

arthopod bite hypersensitivity reactions can have puritic to tender nodules ___ cm in diameter that last for weeks. Associated ____. Excoriation and impetiginization common.

-2 cm


-lymphadenopathy

____ are the most common skin lesion for arthropods

flea bites

flea bites are one to three bites, multiple often ____.

linear (breakfast, lunch, dinner)

flea bites lead to ____ infection, common in kids.

secondary

no insect repellents under age?

2 months

insect repellent


____% DEET or ____% picaridin safe in children 2 months and up

-30% DEET


-20% picaridin

___ is for clothing only

permethrin

oil of lemon eucalyptus is not recommended for kids under ____

3 years

topical steroids for itching should be class __-__, gels

1-3

for itch relief you can use ____ or camphor based counter-irritants

menthol


(pramegel, sarna, aveno anti itch, itch x)

Oral ____ are also used for anti itching

antihistamines


(diphenhydramine, chlorpheniramine, hydroxyzine, clemastine, doxepin)


-cold compresses

what does a diaper rash irritant rash look like?

-chapped appearance


-poorly defined margins


-spares folds


*desitin and frequent diaper changes

what does a diaper rash candidal rash look like?

-well defined


-glistening surface


-collarette of scale


-satellies

what does a seborrheic diaper rash look like?

-poorly defined


-confluent erythema


-fine scale throughout

what does a psoriactic diaper rash look like?

-well defined


-sharp edges


-white scale


-bleeding when scale picked off


-involves scrotum and folds

seborrheic dermatitis aka?

craddle cap

what does seborrheic dermatitis look like?

-greasy yellow scale


-minimal erythema


-scale and diaper areas common then axilla

child form of seborrheic dermatitis is?

-dandruff


*don't forget tinea in child 1-10 years

hemangiomas are a dynamic process


flat at birth


grow to ___ birthday


then start to ____

-1st birthday


-involute

what are problematic areas for hemangiomas?

-face


-neck


-periorbital


-perineal


-midline back

the hemanigoma may have underlying pathology...

1. airway compromise on neck


2. kidney compromise on back


3. PHACES syndrome

capillary malformations are known as

port wine stains

fixed lesion, no proliferative phase, may enlarge over time

port wine stain

___ ___ are present in 1% of babies and small <20 cm are most common. may have increased risk of melanoma.

congenital nevi

flat tan macules and patches

cafe au lait

if cafe au lait spots are numerous (6 or more) or large (>5cm) they may suggest

syndrome


-no increased cancer risk

honey crusted or bullous lesion?

impetigo

impetigo is almost always caused by ____ ___.

staph aureus

to treat impetigo use an antibiotic effective against staph such as?

-augmentin


-cephalosporin

impetigo can be ___ but is most commonly MSSA

MRSA

treatment of MRSA infections:


uncomplicated infections

incision and drainage alone

treatment of MRSA infections


minor skin infections like impetigo can be treated with topical ____ alone

mupirocin (bactroban)

treatment of MRSA infections


if oral antibiotics are needed use?

-clindamycin


-bactrim


-tetracycline (over 9)


-linezolid

recurrent MRSA infections

-good hygiene


-covered with dry dressings


-avoid sharing personal items

you decolonize MRSA if?

all above personal hygiene measures are met

how to decolonize MRSA?


mupirocin

-BID for 5-10 days

how to decolonize MRSA?


chlorhexidine baths


bleach baths

-daily 5-14 days


-15 mins twice a week for about 3 months

how much bleach in a bleach bath?

-1 teaspoon per gallon or


-1/4 cup per 1/4 tub

do you give oral antibiotics for decolonization of MRSA

Nope

most effective treatment for MRSA skin infections?

-mupirocin plus bleach baths

which students are at the highest risk for MRSA?

contact sport athletes


-football and wrestling

how long are you band from contact sports with a MRSA infection?

-on antibiotics for 72 hours


-no new lesions for 48 hours


-no active moist or draining lesions

multi system disease caused by staph aureus exotoxin, originally due to tampon use now most are non-menstrual

staph toxic shock syndrome

symptoms of toxic shock syndrome


-fever:


-diffuse macular _____


-desquamation __-__ weeks after onset of illness


-hypotension


-involvement of __ or more systems (GI, muscular, CNS, renal, hepatic, mucosal, hematologic)


-lack of evidence for other causes

-fever: >38.9


-diffuse macular erythroderma (suburn like)


-desquamation 1-2 weeks after onset of illness


-hypotension <90


-involvement of 3 or more systems (GI, muscular, CNS, renal, hepatic, mucosal, hematologic)


-lack of evidence for other causes

____ toxic shock syndrome is less common than staph form. usually due to deep seated infection

strep

case definition of strep toxic shock

-isolation of strep pyogenes


-hypotension


-two or more


*renal impairment


*coagulopathy


*hepatic involvement


*ARDS


*generalized erythematous macular rash, +/- desquamation


*soft tissue necrosis

produced by split in the granular layer of epidermis due to exfoliative toxins A or B

staph scalded skin syndrome

what age usually gets staph scalded skin syndrome?

younger than 5, can be any age though

tender diffuse scarlatinform erythema with perioral crusting and superficial fissuring may progress to full skin desquamation; worse in folds

-staph scalded skin syndrome

nikolsky sign is?

skin sloughing off when pressed on

the ___ are spared in staph scalded skin syndrome

mucosa

to treat staph scalded skin syndrome use?

penicillinase resistant beta lactam +/- clindamycin to stop toxin production

perianal strep cellulitis is mostly due to ?

group A strep

perianal strep cellulitis has perianal and perineal irritation, ____ and pain, as it progresses ____ becomes painful.

-itching


-defecation (leads to encopresis and rectal bleeding)

what is the first line for perinal strep? alternatives?

-penicillin V


-other beta lactams or macrolides

what is the characteristic hemorrhage of meningococcemia?

-large petechiae or stellate (star shaped) purpura


-universal distribution of hemmorrhages

hemmorrhage in meningococcemia should have one or more greater than ___ in diameter

-2 mm

two other variables in meningococcemia?

-poor general condition


-nuchal rigidity

if two or more variables of meningococcemia are present the probability of the disease is ?

97%


-other causes enterovirus, adenovirus, other bacteria

viral exanthems can be in what forms?

-erythematous


-papular


-vesicular

most viral exanthems are ?

erythematous (morbilliform, scarlatiniform)

associated signs of viral exanthems?

-fever


-malaise


-HA


-myalgia


-respiratory


-GI symptoms

how long does it usually take for a viral exanthem to resolve?

1 week

what are the causes of viral exanthems

-enteroviruses


-adenovirus


-rhinovirus


-parainfluenza


-RSV


-influenza

in the warmer months viral exanthems are from?


colder months?

warm: enterovirus


cold: respiratory virus

skin petechial exanthems are caused by?

-enterovirus, EBV, CMV, menigococcemia, gonococcemia, RMSF, HS purpura, rate bite fever, ehrlichiosis, dengue fever, leptospirosis

mucosal petechial exanthems are caused by?

-group A strep, rubella, EBV, arcanobacterium hemolyticum

____ is associated with a non-specific macular exanthem and gianotti-crosti syndrome

hepatitis B

hepatitis B vaccine is been reported to cause?

-urticara


-erythema nodosum


-erythema multiforme


-lichen planus


-lupus


-buccal aphthosis


-periarteritis nodosa

papular acrodermatitis, symmetric flat topped papules/vesicles on face, buttocks, extensor extremities

gianotti-crosti syndrome


(papulovesicular acrolocated syndrome)

how long dies gianotti-crosti syndrome last?

-3 weeks in most


-up to 12 weeks

etiology of gianotti-crosti?

-EBV


-coxsackie A16


-parainfluenza


-CMV


-RSV


-parvo B19


-HHV-6


-rotavirus


-hep B


-immunizations

when can you have skin reaction from Hep B vaccine?

within two months of shot

painful vesicles and shallow erosions throughout the oral cavity, dehydration is major concern, hurts too much to drink

herpes simplex virus


(gingiviostomatitis is primary infection in kids)

recurrent herpes labialis is most common in?

adults

herpes gladiatorum: wrestlers will be ?

disqualified

____ are occupational hazard in health care workers

whitlow

____ ____ is generalized HSV in patient with primary skin disease such as atopic derm

eczema herpeticum

non-enveloped DNA virus that targets erythroid progenitor cells

parovirus B19

intranasal exposure to parvo causes viremia in __-__ days

5-6 days

what is the viremic phase of parvo?

-fever


-malaise


-myalgia


-headache


-asymptomatic

peak viremia of parvo causes?

pancytopenia

IgM antibody phase of parvo?

-rash


-arthralgia


-arthritis

clinical association of parvo?

-erythema infectiosum


-arthropathy/arthritis


-transient aplastic crisis


-chronic anemia


-hydrops fetalis


-neuro dx


-rheumatic disease


-vasculitis

fifths disease occurs in children __-__ years old in ___ and ___.

-4-15 years


-winter and spring

prodrome of fifths disease?

-respiratory symptoms


-low grade fever

fifths disease has eruption on ___ phases

3

first phase of fifths disease

slapped cheek-facial erythema

second phase of fifths

lacy reticular eruption

third phase of fifths?

recrudescence with heat, sunlight, exertion

when does fifths disease resolve?

-spontaneously in 1-2 weeks

parvo can cause ___/___ in 8% of kids

-arthralgia/arthritis


*asymmetric, pauciarticular (knees)

acute self limited distinctive exanthem of hands and feet?

papular-purpuric gloves and sock syndrome

rapid onset of petechial and purpuric papules on drosal hands and feet with subsequent involvement of plamoplantar surfaces

papular-purpuric gloves and sock syndrome

papular-purpuric gloves and sock syndrome


sharp ____ proximally is the rule, may be accompanied by fever, malaise, anorexia, arthralgias and myalgias

-demarcation proximally

papular-purpuric gloves and sock syndrome resolves in __-__ weeks with out sequelae. most causes do to?

-1-2 weeks


-parvo B19 (coxsackie B6 and CMV too)

unilateral frequently becoming bilateral with continued accentuation on the originally effected side?

asymmetric periflexural exanthem of childhood


(unilateral laterothoracic exanthem)

median age for papular-purpuric gloves and sock syndrome?

18-24 months

what are common things in papular-purpuric gloves and sock syndrome?

-prodrome


-pruritis


-lymphadenopathy

how long does papular-purpuric gloves and sock syndrome take to resolve

-most by 3-6 weeks

tinea corporis is a fungal infection with the most common organisms being

-T. tonsurans


-M. canis


-T. rubrum


-T. mentagrophytes

if tinea corporis is facial, think _____ or pet.

scalp

_____ can have a similar rash in tinea corporis

siblings

raised ring with erythematous borders, scale, central clearing

tinea corporis

how do you treat tinea corporis?

-azoles or allyamines (OTC)


(not nystatin)

common infection among competitive athletes in contact sports, especially wrestling. round scaly patches with central clearing

tinea gladiatorum

how long do you need therapy before you can go back to sports with tinea gladiatorum?

72 hours and clearance from provider

what is the treatment for tinea gladiatorum?

-topical azoles (clotrimazole, econazole, miconazole)


-allylamines (terbinafine)


*twice per day until clear

classic ringworm pattern, kerion, seborrheic pattern, patchy alopecia (+/- black dots), folliculitis pattern-in scalp

tinea capitis

what is the most common organism in tinea capitits?

trichophyton tonsurans

____ pattern on KOH for tinea capitis

endothrix

in about half of tinea capitis cases there is an ____ ____.

asymptomatic carrier

what is the oral treatment of choice for tinea capitis?

-griseofulvin


*11mg/kg/day approved but requires 20mg/kg/day

although griseofulvin is the treatment of choice, ____ has shown to be more effective

terbinafine


*itraconazole and fluconazole also effective

for tinea use what shampoo?

selenium sulfide 2.5%

in tinea capitis you must eliminate ____ by sterilizing or replacing brushes, combs, hats, bows, ribbons etc

fomites

seborrhea between ages 1-10 years should be considered ____ until proven otherwise

tinea

griseofulvin doses below ____ are not effective

20mg/kg/day

intensely itching, highly contagious, crusted small papules, linear burrows, erythematous papules

scabies

where are scabies found?

-finger webs


-wrists


-forearms


-trunk


-extremities


-genitalia


-soles of feet in babies

what do you treat scabies with?

permethrin 5% cream overnight

if permethrin doesnt work or if it is a crusted variant scabies use oral _____

ivermectin

how long do female lice live and how many eggs do they lay per day?

-3-4 weeks


-10 eggs/day

typical hatch time of lice?

8-9 days

topical therapeutic options for lice?

-permethrin


-pyrethrin/piperonil butoxide


-malathion


-benzyl alcohol


repeat permethrin, prethrin/piperonil butoxide and benzyl alcohol in __ days

9

do not use _____ shampoo, agents interfere with residue effect

conditioning

malathion gets applied to ____ hair and is highly _____. Only repeat in 9 days if lice is seen

-dry


-flammable

what is the new lice treatment?

-natroba topical suspension spinosad 0.9%


-shown to be more effective than permethrin

oral therapy for head lice is ____ ____

not recommended


-not fda approved

____ ____ measures for lice are not approved. vinegar, mayo, petrolatum, olive oil, butter, isopropanol, water immersion and hair removal have not been proven effective.

non-pharmacologic

manual combing with fine tooth nit removal combs is okay and is best with ____ hair. do not need to remove dead lice. no chemical loosening has been effective. no bug zappers either

wet

head lice


most products are not completely ovicidal must repeat in ___ days.

9

____ is no longer recommended for head lice

lindane

no ___ policies at schools are inappropriate

nit

remove the pediculocides over the ____ (not shower or bath) using warm water.

sink

percutaneous penetration of the larval dog or cat hookworms usually after exposure of bare skin to moist sandy soil.

cutaneous larva migrans

in cutaneous larva migrans, larvae will migrat for a few ___ to ____ and then die.

days to weeks

serpiginous track that follows the path of the ____

worm

what are treatments for cutaneous larva migrans?

-oral albendazole


-oral ivermectin


-topical thiavendazole

there is not enough evidence to show that any particular treatment is effective for treating ____ infection.

molluscum

efficacy of salicylic acid in warts

60-80%

efficacy of balneotherapy in warts?

77-95%

efficacy of cryotherapy in warts?

50%

there is no data for these wart treatments

-imiquimod


-tretinoin


-5-fluorouracil


-pulsed dye laser

there was no difference between cryosurgery and salicylic acid in warts but ____ was more expensive

cryotherapy

cryotherapy is not tolerated due to what side effects?

-pain


-blistering


-pigment changes


-scarring

cantharidin for molluscum treatment is not fda approved because it is toxic but produces painful-nonpainful blisters that scab off in __-__ days

5-10

what are the side effects for tinea capitis treatment?

-HA


-fever


-nasopharyngitis


-GI complaints

warts and molluscum resolve spontaneously in ___ to couple ___

months to years

65% of warts disappear in ___

2 years

most molluscum disappear in __-___

6-9 months