306 Drugs Unit 1

Front 1

2nd generation sulfonylurea for type two diabetes that stimulates insulin production and improves response of body to insulin. Taken at 5-40 mg a day. Side effects include n,d,ha,weakness,hypoglycemia. Nurse must monitor ALT, SGPT, cr, jaundice bs. given 30 minutes ac meals

Back 1

glucotrol: Glipizide

Front 2

Sulfonyurleas work by

Back 2

stimluating insuline production but also improving repsonse of body to insulin

Front 3

When is hte best time to give a second generation sulonlylurea such as glucotrol?

Back 3

30 min ac meal

Front 4

Thiazolidinedione for type two diabetes. Works by improving response of body to insulin and decreasing hepatic glucose output. GIven in 4-8 mg a day with sid effects of ha, uri, edema, d, hypog, hepatoxicity. Monitor alt, sgbt, cr, jaundice, bs. and give without regard to meals?

Back 4

Rosiglitazone maleate: Avandia

Front 5

_______ for type two diabetes can be given without reference to meals, thiazolidinediones such as avandia.

Back 5

tthiazolidinediones such as avandia.

Front 6

Thizolidinediones work by

Back 6

improving response of body to insulin and decreasing hepatic glucose output

Front 7

Thiazolidinediones are toxic to the _____ so what must be monitored?

Back 7

liver, ALT, Sgbt,

Front 8

thiazolidinedione for type two diabetes that works by improving response to insulin and decreasing hepatic glucose output given in 15-45 mg/ day. Sx inlcud eheadache, uri, edema, diarrhea, hpoglycemia, ha, RN must monitor alt, sgpt, cr, jaundice, bs. given without regard to meals

Back 8

Actos Pioglitazone

Front 9

Side effects of actos or pioglitazone a thiazolidinedione are

Back 9

hypoglycemia, headache, diarrhea, URI, edeam, hepatoxicity

Front 10

alpha glucosidase inhibitor for type two diabetes that works by decraseing absorption of complex cArbohydrates. Given at 150 to 300 mg a day with side effest of diarrhea, ab pain, and flatulence. Nurse must monitor alt, ast, cr, bs. Give with first food bite.

Back 10

Glyset: miglitol

Front 11

______ such as glyset or miglitol has side effects of diarrhea, ab pain, and flatulence

Back 11

alpha glucosidase inhibtors

Front 12

Drug class for type two diabetes that decrases absorption of complex carbohydrates

Back 12

alpha gluosidase inhibitors

Front 13

alpha glucosidase inhbitor for type 2 diabetes that decraeses absorption of compelx carbs given in 25-300 mg a day with sid effects of ab pain, diarrhea nad flatulence. RN must monitor alt, ast, bs, and creatinine

Back 13

Precose: acarbose

Front 14

Precose(acarbose) glyset(miglitol) are ______ that must be given _____

Back 14

alphaglucosidases inhibitors given with first bite of food

Front 15

meglitinide for type two diabetes that stimulates insulin production in pancreas given in .5 to 16 mg a day with side effects of arthralgia, diarrhea, hypoglycemia, uri.

Back 15

Prandin; repaglinide

Front 16

Meglitinide for type two diabetes works by

Back 16

stimulating production of insulin by the pancreas

Front 17

biguanide for type two diabets that iimproves response of body to insulin, decreases gluconeogenesis and decreases hepatic glucose output. given 500 to 2550 mg a day with side effedgs of n,v,d, lactic acidosis. rn must not given with dye, monitir renal fialure, and is good for some overweight people

Back 17

metformin: glucophage

Front 18

Signs of lactic acidosis for metoformin in clude

Back 18

hyperventilation, somnolence, myalgia, malaise, chills

Front 19

Don't give this drug before a ct scan with dye?

Back 19

metformin: glucohage

Front 20

2nd generation sulfonyruea for type 2 diabetes that stimluates insulin production and improve respoinse with 1.25 to 20mg a day, Side effects n,d, ha, weakness, hypoglycemia. RN monitors alt, sgpt, jaundice, Give 30 minutes ac meal

Back 20

glyburide: Diabeta or Micronase

Front 21

2nd gernation sulfonurea for type 2 diabetes that stimluates insluin rpoduction and improves the bodies response. given at 1-8 mg a day with side effedts of n, d, ha, waekness, hypoglycemia. Montir AL, sgpt, jaundice, bs . give 30 min ac meal

Back 21

glimepridie: Amaryl

Front 22

which drug class stimulates insulin production? and improves bodies repsonse to insulin?

Back 22

second gernation sulfonureas including glimepiride, glipizide

Front 23

anticoagulatn that depresses hepatic synthesis of Vit K dependant cotting factors with an slow onset with in 5-7 days taken by mouth. Patient should be monitored for bleeidg and hemorrage and Vit K is antidote

Back 23

Coumadin: warfarin

Front 24

Antidote to Coumadin

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Vit K Aquamephyton

Front 25

anticoagulant to treat and prevent dvt and emoboli by potentiating actio nfoantithrombin 3, blockign conversion of prothrombin to thrombin and fibringogen to fibrin. Given IV or SQ, wiht side effedcts of anemia, thrombocytopenia and bleeding. Nuse should montiro aptt, hematocrit and platelts. Antidote is Protamine

Back 25

Heparin

Front 26

Antidote to heparin

Back 26

Protamine

Front 27

anticoagulant that blocks factor 10 preventing conversion of fibrinogen to fibrin prothrombin to thrombin and inhibitors antithrombin3, and inhbitors facotr 10. It is active for 24 hours and is given SQ at around 1mg/ kg. Patient must be monitored for anemia, thrombocytopenia, bleeding, burisng, Contraindicated in uncotrollleb ledidng. REduce dose by 1/2 for renal insufficency antitdote is fresh frozen plasma

Back 27

Lovenox: enoxaparin

Front 28

Reduce dose by half of lovenox for what disease?

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renal insufficency

Front 29

Lovenox is given

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SQ.

Front 30

Antidote to Lovenox is?

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Fresh frozen plasma

Front 31

aspirin works by

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blocking syntehsis of thromboxane 2 that aggregates platelets and vasoconstricts

Front 32

adverse side effects of aspirin in clude

Back 32

gi bleeding, tinnitis, wheezing, bronchospasms, antioedema, dyspepesia

Front 33

antiplatelet aggregate agent that permanantly blocks adp receptor site on platelt given po. side effecgs include gi upset, bleeding hemorrage and ttp

Back 33

Plavix or clopidogril

Front 34

hydrochlorothiazide HCTZ and metolasone are

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thiazide diuretics

Front 35

thiazide diuretics work by __________ in distal renal tubule.

Back 35

increasing excretion of Na

Front 36

This HTN med works by inhibiting reabsoprtion of NA and CL in loop of Henle (and tubules)

Back 36

loop diuretics: furosemide and turosemide

Front 37

Furosemide and torsemide are

Back 37

loop diuretics

Front 38

K may become severely depleeted in this type of medication

Back 38

loop diureitcs

Front 39

K may become very high i this type of htn medication 2

Back 39

ace inhibitors (prils) and angiotensin 2 receptor antagonist SARTANs

Front 40

captopril, enalapril, and lisinopril are

Back 40

ace inhibitors

Front 41

how do ace inhibitors work?

Back 41

block renin blcoking conversion of angiotensin 1 to antiotensin II which would cause vasoconstriciton. also decrase aldosterone levels promoting na excretion

Front 42

Ace inhibitors work by blocking_____, blocking conversion of _____ to _____ which served to vasoconstrict. It also serves to decrease _____ levels promoting ____ excretion

Back 42

renin, antiotensin 1, angiotensin 2,, aldosterone, NA

Front 43

angioedema is a bad side effect along with cough and dizziness seen in

Back 43

ace inhibitors