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96 Cards in this Set

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What is a neuron made of-that have the same as cells?
membrane
cell body (soma)-entire egg
nucleus-yolk of egg
What is a soma?
the cell body-integrates the information
what parts of the neuron are "special"?
axons-axon terminals-sends info to next neuron
dendrites-RECEIVES new information
both are extensions on the neuron-long squiggly things
What is an axon?
SENDS information to the next neuron
what are dendrites?
they RECEIVE new information
The sodium potassium pump consumes a lot of energy-which is why we need to do what?
it pushes the ______ against cells, and brings _____in the neurons
eat
sodium
postassium
the more sodium pumped out...the more _________
membrane potential (-70mV)
when is an action potential triggered?
when the resting membrane potential (-70mv) crosses -50mv
when does an action potential peak?
30mv
information is coded by RATE/SIZE in action potentials?
rate
when membrane potential reaches threshold...what happens?
Na channels open
K channels open
what is transduction?
conversion of a physical stimulus to a neural response
physical stimiulus-neural
where are neurotransmitters released?
in the SYNAPTIC CLEFT when AP reaches an AXON terminal
what sensory neurons go with the sense of TOUCH?
MERKEL receptor
PACINIAN corpuscle
what sensory neurons go with the sense of PAIN?
heat NOCICEPTORS that are also activated by capsaicin
what sensory neurons go with the sense of PROPRIOCEPTION (sense of self)
Muscle spindle fibers that detect stretch
what sensory neurons go with the sense of OLFACTION?
olfactory sensory neurons
what sensory neurons go with the sense of TASTE?
taste cells (in the taste bud)
what sensory neurons go with the sense of BALANCE?
hair cells
where is the 1st synapse for TOUCH?
in the BRAINSTEM (top of the spinal cord)
where is the 1st synapse for PAIN?
in the SPINAL CORD
where is the 1st synapse for PROPRIOCEPTION (sense of self)
in the SPINAL CORD
where is the 1st synapse for OLFACTION?
in the olfactory bulb (GLOMERULUS)
where is the 1st synapse for TASTE?
in the taste bud
where is the 1st synapse for BALANCE
in the inner ear
were is the primary cortical area for the sense of TOUCH?
post-central gyrus
were is the primary cortical area for the sense of PAIN
post-central gyrus
were is the primary cortical area for the sense of PROPRIOCEPTION?
post-central gyrus...but some processing is done in the spinal cord
were is the primary cortical area for the sense of OLFACTION?
piriform cortex, orbitofrontal cortex
were is the primary cortical area for the sense of TASTE?
frontal operculum and insula
were is the primary cortical area for the sense of BALANCE?
NONE-vestibular nuclei are in the brainstem
what does it mean when a neuron adapts?
even though the stimulus continues, the rate of AP slowly returns to the resting state.
Some return to the resting state faster than others.
what happens to the spiking rate of a neuron when a stimulus is first applied?
sensory neurons increase or decrease their spiking rate
Flavor is a combo of what?
taste and smell
appetite is a combo of what?
flavor
vision
texture
pain is a combo of what?
touch and pain
what are the psychophysical techniques of measuring absolute thresholds? (3)
Method of Limits
Method of Adjustments
Method of constant stimuli (Fechner)
increasing and decreasing stimulus intensity to measure threshold
method of limits (Fechner)
turning up and down the volume
method of adjustment (Fechner)
randomly presenting the stimuli at various intensities-then measure the % they detected.
method of constant stimuli (Fechner)
CoNstaNT
what is the psychophysical technique for measuring the difference threshold?
difference method-JND (Weber's law)
what is Weber's Law?
JND
describes the phenomenon that the magnitude of a barely perceivable change (JND), in comparison to the magnitude of the stimulus, is constant
JND
what is top-down information processing?
modulation of neural responses by attention or some other behavioral sate or experience
starts with big-picture and starts breaking it down
what is bottom-up information processing?
when some neurons in the primary sensory areas can fail to respond to a stimulus if we are paying attention to someting else
what does a negative membrane potential (-70mv) mean?
there is a higher concentration of positively charged ions outside the cell than inside.
what kind of fibers are used when you experience the sharp bain from stubbing your toe? (info goes to brain quickly)
large, mylinated fibers
what kind of fibers are used when you experience slow, aching pain? (pain from mechanical/thermal)
C fibers-small, unmylinated fibers...reaches the somatosensory cortex 2 seconds after the sharp pain.
what is weber's ovbservation?
as the stimulus magnitude (S) increases, the JND increases
JND/S=K
what is stephen's law?
doubling intensity/magnitude rarely doubles in response
on a scale of 1-5 how strong is the stimulus
P=KS^n
what is a psychometric function?
a curve of the person's response to a stimulus
-ex. as stimulus intensity increases, persons response increases
when action potential reaches an axon terminal, where are neurotransmitters released?
in the synaptic cleft
a bundle of axons is a _____.
nerve
what is the CNS made of?
brain & spinal cord
what is the PNS made of?
spinal nerves and cranial nerves
what type of sensation does TOUCH create?
mechanical & thermal
-mechanical displacements of the skin (poked, licked by dog, kissed, etc.
what type of sensation does PAIN create?
mechanical
thermal
chemical
Where will you find the cell body of a Pacinian corpuscle that detects vibrations in your right fingertip?
in the DR ganglion on the R side of the spine.
when you wrap your fingers around a coffee cup and feel that it is pleasantly warm, what is the geometry of the neuron that detects this wamth?
a bipolar neuron with cell body in the DR ganglion, free nerve endings embedded in the skin, and an axon that projects to the spinal cord.
where do cell bodies of bipolar neurons live?
DORSAL ROOT GANGLION (right side of spine)
what kind of neuron is most strongly stimulated when you read braile?
Merkel receptors
where is the post central gyrus located?
in S1=the primary somatosensory cortex
-sense of TOUCH
what does it mean when we say a neuron in primary somatosensory cortex is feature-selective?
the neuron responds to local "features' of an object, like the orientation of an edge
why is it hard to ignore pain?
nociceptive neurons in the spinal cord project to the LIMBIC system as well as the THALAMUS
What is a pain killer in the CNS?
morphine (not aspirin/advil/tylenol)
linear and angular acceleration are transduced in the occipital lobe/vestibular nuclei/inner ear/middle ear?
inner ear
where in the brain is the primary cortical representation of balance?
there is NO primary cortical balance area
T/F Woerneke's area contributes to your sense of balance
false
are thermal receptors uniformly distributed?
no
they also have free nerve endings
what are the limits of sensing heat and cold for thermal receptors?
they sense heat and cold up to the limit where it is damaging.
merkel receptors are fast/slow adapting?
Big/small receptive fields?
located where?
slow
small
located at dermis/epidermis
pacinian corpuscles: are
fast/slow adapting?
big/small receptive fields?
located where?
fast
big
located in subcutaneous fat
merkel receptors are continuous or only activate AP on on/off stimulation?
continuous
fine details (not moving)
pacinian corpuscles are continuous or only active AP on on/off stimulation?
on/off stimulation
vibration
moving over fine details
Vestibular sense: SUMO
Saccule
Utricle
Maccule
Otolith
sense linear acceleration of the head
Vestibular sense: SNAC
Semicircular
caNals
Ampula
Cupula
angular motion
cilia of hair cells in the _____ of s/u sense shift of____ membrane during linear acceleration.
macula
otolith
cilia of hair cells in the _____of semicurcular canal sense shift of _______ during angular acceleration.
ampula
cupula
Vestibular information is processed in _____ nuclei.
brainstem
NOT the brain (subconscious)
Vestibular nuclei integrate 3 things to control our balance: what are they?
vestibular sensation, optic flow, and other proprioceptive cues to control our BALANCE
_____results from disturbance of the inner ear.
Vertigo
comes from inflammation/migraine/change in semicircular canals from drinking alcohol)
Balance is maintained by 3 things:
kinethesia
vision
vestibular info
motion sickness results from?
cue conflict (knesthesia, vision, or vestibular info don't agree)
or postural instability
oflactory neurons have molecular receptors embedded in their _____, which stick out into the mucus of the olfactory mucosa
cilia
t/f there is a 1:1 mapping between shape and receptor response
false
1 molecule is enough to elicit an AP from an olfactory neuron.
synapses from olfactory neurons with the same receptor type are grouped in ________ in the olfactory bulb.
glomeruli
organization of glomeruli across olfactory bulb is sensible with respect to odorant molecule structure
t/f we have a growing ability to predict sense (pleasantness) from a molecular structure
true
olfactory information bypasses the ______
thalamus
from the olfactory bulb------piriform cortex.
what are the 4 types of papillae on our tongue?
which 3 have taste buds?
FUCFO
fungiform, circumvillate, foliate, and filliform
FUCFO has tastebuds
FI doesn't
what are the 5 types of taste neurons?
bitter
sweet
umami
salty
sour
molecules (bitter, sweet, umami) and ions (salty, sour) contact receptors on cilia in taste cells through taste pores at top of ______ ___.
taste bud
t/f supertasters have a higher density of filliform papillae on tongue
FALSE
higher density of fungiform
t/f taste intensity is a expansive function
FALSE
compressive
where are the bipolar neurons of taste information?
Nucleus of the solitary tract
secondary afferent neurons in Neucleus of the solitary tract then project to the THALAMUS. then taste info goes to INSULA then FRONTAL OPERCULUM IN CORTEX
capsaicin activates/represses thermal nociceptors in tongue. Capaicin cream can be used to increase/decrease reactivity nociceptors inovlved in neuropathic pain
activates
decrease
Anosmia is the lack of what?
the sense of smell
blood glucose inhibits firing rate of what?
Neucleus of the solitary tract
NST