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19 Cards in this Set

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  • Back
Arteriography shows narrowing of radius by 50%. What is the expected change in blood flow?
Decrease radius by 1/2-->Increase resistance 1/16

Thus flow will decrease to 1/16
When a person moves from a supine position to a standing position, what compensatory changes occur?

Why?
Standing will DECREASE venous return, DECREASE cardiac output, DECREASE arterial pressure

Need to INCREASE contractility to INCREASE HR
What does an increased ejection fraction signify?

What is its effect on end-systolic volume?
EF = SV/EDV

An increase in EF means a higher fraction of end-diastolic volume is ejected in stroke volume (could be due to administration of a positive inotropic agent). When this occurs, the volume remaining in the ventricle after systole DECREASES.
If HR is 70 bpm, calculate cardiac output.
SV = 140-60 = 80

Q = 80 * 70 = 5600 mL = 5.6 L
The ventricles are completely depolarized in which isoelectric portions of the EKG?
Only isoelectric segments of EKG are PR and ST

Ventricular depol occurs during ST
Patient develops orthostatic hypotension after sympathectomy.

This is due to a/n [exaggerated/suppressed] response of the baroreceptor mechanism.
Suppressed bc no longer has sympathetic circuit to increase HR/contractility
The dashed line in the figure illustrates the effect of __________.
Increased contractility
The dashed line in the figure illustrates __________.
Increased blood volume, thus, increased mean systemic pressure
How can venous pressure be modified to increase tendency for edema to occur?
Increased venous pressure will increase tendency for edema.
The upstroke of the action potential in the SA node is due to the influx of ______.
Ca2+
The upstroke of the action potential in Purkinje Fibers is due to influx of ______.
Na+
In the SA node, phase 4 depolarization is attributable to ______.
Increase in Na+ conductance
alpha1 vs beta2 effects
alpha1: Vasoconstriction of arteriolar smooth muscle

beta2: VasoDILATION of arteriolar smooth muscle
During which phase of the cardiac cycle is aortic pressure highest?
Reduced ventricular ejection (right after rapid ventricular ejection ends)
What is the effect of histamine on arterioles?
Dilation
During which phase of the cardiac cycle is ventricular volume lowest?
Isovolumetric ventricular relaxation; volume ;lowest when ventricle is relaxed (diastole)
During which phase of the ventricular action potential is the conductance to Ca2+ highest?
Phase 2 of plateau (right before repolarization)
Aldosterone vs ADH
ADH: increase arterial bp, increases water permeability of distal tubule and collecting ducts

Aldosterone: Indirectly increases water resorption via retention of Na+
EF 0.4
HR 95 bpm
Q 3.5 L/min

EDV?
EF = SV/EDV

Q = HR x SV

=92 mL