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38 Cards in this Set

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pathogen too big to be phagocytized, throw toxic molecules at larger pathogen to destroy it
ADCC
kill bacteria and fungi but not spores and non-enveloped viruses, acts by protein denaturation
Alcohol
response to antigens--made by B cells
Antibodies
have MHC class I & II, display antigen, migrate to naive lymphocytes and activate only ones that are recognized by pathogen
APC
makes antibodies
B-cell
have basic granules and release histamine, ONLY in blood
Basophil
1st compliment activated in classical pathway
C1/C4/C2
only common molecule in all pathways
C3
cells in respiratory system, bacteria try to eliminate cilia
Ciliated Stratified/Pseudostratified Columnar Epithelium
Crosslinking of BCR
Signal 1 for B cell activation
chemical messengers from T-h cells that help T-c cells or B cells
Cytokines
APC, gathers antigen from tissues and then present it to lymphocytes that congregate in secondary lymphoid organs
Dendritic Cells
produces mucous
Goblet cells
type of leukocyte, has large granules: neutrophils (PMN's), eosinophil, basophil
Granulocyte
IgA
monomer or dimer; found in SECRETIONS. Most abundant overall antibody
IgD
on the surface of B cells
IgE
in allergies, used in ADCC and to get rid of PARASITES
IgG
monomer, used in classical compliment and ADCC and is able to cross the placenta
IgM
first antibody produced; pentamer, no Fc region, stays in the blood stream and used in classical complement activation
interferon y
makes angry killer macrophage
Lactoferrin
iron binding protein, bactera need iron and it prevents access to free iron
Lymphocyte
T/B/NK cells, highly specific, only recognize few antigens
Lysozyme
breaks down peptidogylcen--most effective against gram positive
MAC complex
puts holes in antigen, C6-9
Mast Cells
similar to basophils, release histamine and not found in blood
MHC Class I
found on all cells
MHC Class II
found on APC's
Neutrophil
PMN-first cell to respond, not activated or educated--most abundant
NK cells
kill cells that have been bound to antibody or abnormal, always kill and look for avsence of MHC class I which turns off
Plasma Cell
B cell that actively secretes antibodies
Signal I
binds to MHC
Signal 2
special handshake between APC and T/B/ cell
Stratified Squamous Epithelium
overlapping epithelial cells that become kertinized to seal the surface of our body
T cell
develop in thymus, Tc destroy infected/abnormal host cells
Type I hypersensitivity
allergies (IgE) very rapid
Type II hypersensitivity
blood clots (IgM and IgG)
Type III hypersensitivity
small antigen-antibody complexes form and deposit in sites--causes inflammatory response (IgG)
Type IV hypersensitivity
only in T cells--take a long time