2Nd Set Of Micro Vocab

Front 1

pathogen too big to be phagocytized, throw toxic molecules at larger pathogen to destroy it

Back 1

ADCC

Front 2

kill bacteria and fungi but not spores and non-enveloped viruses, acts by protein denaturation

Back 2

Alcohol

Front 3

response to antigens--made by B cells

Back 3

Antibodies

Front 4

have MHC class I & II, display antigen, migrate to naive lymphocytes and activate only ones that are recognized by pathogen

Back 4

APC

Front 5

makes antibodies

Back 5

B-cell

Front 6

have basic granules and release histamine, ONLY in blood

Back 6

Basophil

Front 7

1st compliment activated in classical pathway

Back 7

C1/C4/C2

Front 8

only common molecule in all pathways

Back 8

C3

Front 9

cells in respiratory system, bacteria try to eliminate cilia

Back 9

Ciliated Stratified/Pseudostratified Columnar Epithelium

Front 10

Crosslinking of BCR

Back 10

Signal 1 for B cell activation

Front 11

chemical messengers from T-h cells that help T-c cells or B cells

Back 11

Cytokines

Front 12

APC, gathers antigen from tissues and then present it to lymphocytes that congregate in secondary lymphoid organs

Back 12

Dendritic Cells

Front 13

produces mucous

Back 13

Goblet cells

Front 14

type of leukocyte, has large granules: neutrophils (PMN's), eosinophil, basophil

Back 14

Granulocyte

Front 15

IgA

Back 15

monomer or dimer; found in SECRETIONS. Most abundant overall antibody

Front 16

IgD

Back 16

on the surface of B cells

Front 17

IgE

Back 17

in allergies, used in ADCC and to get rid of PARASITES

Front 18

IgG

Back 18

monomer, used in classical compliment and ADCC and is able to cross the placenta

Front 19

IgM

Back 19

first antibody produced; pentamer, no Fc region, stays in the blood stream and used in classical complement activation

Front 20

interferon y

Back 20

makes angry killer macrophage

Front 21

Lactoferrin

Back 21

iron binding protein, bactera need iron and it prevents access to free iron

Front 22

Lymphocyte

Back 22

T/B/NK cells, highly specific, only recognize few antigens

Front 23

Lysozyme

Back 23

breaks down peptidogylcen--most effective against gram positive

Front 24

MAC complex

Back 24

puts holes in antigen, C6-9

Front 25

Mast Cells

Back 25

similar to basophils, release histamine and not found in blood

Front 26

MHC Class I

Back 26

found on all cells

Front 27

MHC Class II

Back 27

found on APC's

Front 28

Neutrophil

Back 28

PMN-first cell to respond, not activated or educated--most abundant

Front 29

NK cells

Back 29

kill cells that have been bound to antibody or abnormal, always kill and look for avsence of MHC class I which turns off

Front 30

Plasma Cell

Back 30

B cell that actively secretes antibodies

Front 31

Signal I

Back 31

binds to MHC

Front 32

Signal 2

Back 32

special handshake between APC and T/B/ cell

Front 33

Stratified Squamous Epithelium

Back 33

overlapping epithelial cells that become kertinized to seal the surface of our body

Front 34

T cell

Back 34

develop in thymus, Tc destroy infected/abnormal host cells

Front 35

Type I hypersensitivity

Back 35

allergies (IgE) very rapid

Front 36

Type II hypersensitivity

Back 36

blood clots (IgM and IgG)

Front 37

Type III hypersensitivity

Back 37

small antigen-antibody complexes form and deposit in sites--causes inflammatory response (IgG)

Front 38

Type IV hypersensitivity

Back 38

only in T cells--take a long time