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22 Cards in this Set
- Front
- Back
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50 yr old man
early satiety, bleeding, splenomegaly cytogenetics t(9;22) diagnosis? |
CML
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treatment for AML M3
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retinoic acid
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tumor lysis syndrome
electrolyte changes |
decr Ca2+
incr K, phospate, uric acid |
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differentiate polycythemia vera from secondary polycythemia
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polycythemia
both = incr hematocrit, RBC mass vera = normal O2 satn, low epo |
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TTP pentad
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thrombotic thrombocytopenic purpura FAT RN
Fever Anemia Thrombocytopenia Renal dysfn Neuro abN |
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HUS triad
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anemia
thrombocytopenia acute renal failure (no fever, no neuro abN like with TTP) |
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treatment for TTP
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emergent
large-vol plasmaphoresis corticosteroids antiplatelet drugs |
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treatment ITP in kids
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idiopathic thrombocytopenic purpura
usually resolves spontaneously may req IVG / corticosteroids |
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inc in DIC?
decr in DIC? |
incr = D-dimer, fibrin split products
decr = platelets, fibrinogen, hematocrit |
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8 yr old boy
hemarthrosis, inc PTT normal PT, bleeding time diagnosis? treatment? |
hemophilia A or B
(inc PTT with normal PT = prob intrinsic path = 12, 11, 9, 8) tx A= desmopressin, factor 8 B = factor 9 |
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14 yo girl
prolonged bleeding time after dental surgery, with menses normal PT, normal or inc PTT, bleeding time diagnosis? trreatment? |
von Willebrand dx
tx = desmopressin, FFP or cryoppt |
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Reed-Sternberg cells
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Hodgkins' lymphoma
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60 yo AA man
bone pain work up for multiple myeloma possible findings? |
monoclonal gammopathy
Bence-Jones proteinuria x-ray shows punch lesions in skull & long bones |
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10 yo boy
fever, wt loss, night sweats anterior mediastinal mass suspected diagnosis? |
Non-Hodgkin's lymphoma
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anterior mediastinal mass in boy
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think non-hodgkin's lymphoma
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microcytic anemia with
decr serum iron decr total iron-binding capacity N or incr ferritin |
anemia of chronic disease
decr TIBC, N or incr ferritin indicates sufficient iron available |
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microcytic anemia with
decr serum iron incr total iron-binding capacity decr ferritin |
iron deficiency anemia
incr TIBC, decr ferritin indicates lack of iron |
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80 yo man
fatigue, lymphadenopathy, splenomegaly, isolated lymphocytosis suspected diagnosis? |
CLL
chronic lymphocytic leukemia |
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lymphoma equivalent of CLL
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SLL
small lymphocytic lymphoma |
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late, life-threatening complication of CML
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blast crisis
fever, bone pain, splenomegaly, pancytopenia |
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auer rods on blood smear
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AML
acute myelogenous leukemia |
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AML subtype assoc with DIC
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M3
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