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15 Cards in this Set

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  • Back
3 hallmark symptoms of Acute PostStreptococcal Glomerulonephritis:
-Tea colored urine
-Periorbital edema
-Mild hypertension
Labs that indicate APSGN:
-Hematuria/RBC casts
-Low C3/Normal C4
-ASO/Anti-DNAse B pos
What else could be a cause of dark urine in an otherwise healthy teen?
Strenuous activity with rhabdomyolosis
What other symptoms do teens with rhabdo tend to have however?
-Fever/fatigue/muscle aches
-N/V
What is recurrent, painless hematuria typically caused by?
IgA Nephropathy - Berger's
What is IgA nephropathy typically preceded by?
URI (as opposed to strep pharyngitis)
What nephropathy is typically seen in younger kids?
HSP - henoch schonlein purpura
What other autoimmune nephropathy mimics APSGN but how do you differentiate?
SLE - the C3 will fail to normalize in 6-12 weeks
So what is the defining triad of Glomerulonephritis?
-Hematuria
-Proteinuria
-Mild hypertension
In what sex and age group is APSGN most common?
-Males
-5-15 yrs old
What types of preceding Strep infections can lead to APSGN?
-Pharyngitis
-Impetigo
Does Abx treatment of the preceding infections affect whether the child will develop APSGN?
no
What is the usual time between pharyngitis or impetigo and APSGN?
Pharyngitis 1-2 weeks
Impetigo 3-6 weeks
What is the MOST IMPORTANT lab test in APSGN?
Serum C3/C4 levels
What is the treatment for APSGN?
Supportive - fluid balance