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15 Cards in this Set
- Front
- Back
3 hallmark symptoms of Acute PostStreptococcal Glomerulonephritis:
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-Tea colored urine
-Periorbital edema -Mild hypertension |
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Labs that indicate APSGN:
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-Hematuria/RBC casts
-Low C3/Normal C4 -ASO/Anti-DNAse B pos |
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What else could be a cause of dark urine in an otherwise healthy teen?
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Strenuous activity with rhabdomyolosis
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What other symptoms do teens with rhabdo tend to have however?
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-Fever/fatigue/muscle aches
-N/V |
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What is recurrent, painless hematuria typically caused by?
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IgA Nephropathy - Berger's
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What is IgA nephropathy typically preceded by?
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URI (as opposed to strep pharyngitis)
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What nephropathy is typically seen in younger kids?
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HSP - henoch schonlein purpura
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What other autoimmune nephropathy mimics APSGN but how do you differentiate?
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SLE - the C3 will fail to normalize in 6-12 weeks
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So what is the defining triad of Glomerulonephritis?
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-Hematuria
-Proteinuria -Mild hypertension |
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In what sex and age group is APSGN most common?
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-Males
-5-15 yrs old |
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What types of preceding Strep infections can lead to APSGN?
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-Pharyngitis
-Impetigo |
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Does Abx treatment of the preceding infections affect whether the child will develop APSGN?
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no
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What is the usual time between pharyngitis or impetigo and APSGN?
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Pharyngitis 1-2 weeks
Impetigo 3-6 weeks |
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What is the MOST IMPORTANT lab test in APSGN?
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Serum C3/C4 levels
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What is the treatment for APSGN?
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Supportive - fluid balance
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