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14 Cards in this Set
- Front
- Back
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A-224. What comorbidities are contraindicated in sulfonylureas for T2DM?
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Liver and kidney failure
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A-224. What is elevated in type I, IIa, IIb, III, and IV hyperlipidemias? What is the underlying pathology?
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I: chylomicrons - lipoprotein lipase defect
IIa: LDL - LDL receptor fucked up IIb: LDL and VLDL - possible mutant apoprotein III: IDL - mutant apo E IV: VLDL1 - overprod. of VLDL or underutilization of VLDL |
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A-224. What drugs tx hyperlip. IIa and IIb?
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IIa: cholestyramine colestipol and statins
IIb: niacin, cholestyramine colestipol, and statins |
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A-224. What is the drug of choice for peptic ulcers?
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Omeprazole - proton pump inhibitor
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A-224. What medications are used to treat myasthenia gravis and what is used to diagnose it?
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Tx: Physostigmine and Neostigmine (better for skeletal muscle)
Dx: Edrophonium - MG crisis improves with admin. (inc musc strength). Cholinergic crisis admin reduced muscle stength |
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A-224. What drug is used to tx acute glaucoma and it's most notable side effect?
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Pilocarpine
Miosis - small pupil |
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A-224. Which antinicotinic drug has the least histamine release (less hypoTN and bronchospasm)?
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Pancuronium
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A-224. Weight gain, depression, and hirsutism are signs of excess of this hormone in OCPs?
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Progesterone
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A-224. What street drug acts on 5HT1 & 2 receptors, activates SNS (arousal, tachy, sweating), hallucinations, possible schizophreniform psychosis, and flashbacks?
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LSD
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A-224. What opioid can lead to dependence and what drug reverses morphine OD?
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Dependence: met-enkephalin (endogenous)
Tx OD: naloxone |
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A-224. What are the signs of early and severe lithium intoxication?
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Early: abdominal pain, vomitting, slurred speach
Severe: Peresistant vomit, hyperactive DTRs, coma |
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A-224. What are the key features of caffeine and theophylline (methylxanthines)?
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Smooth muscle relaxation, weak diuretic, enhanced acid secretion in the stomach
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A-224. This benzo is long acting and used to tx alcohol withdrawal.
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Chlordiazepoxide
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A-224. This inhalent for anesthesia is hepatotoxic in adults.
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Halothane
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