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17 Cards in this Set

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A-218. What are the locations and function of Integral and Peripheral proteins in the cell membrane?
Integral: extend entire cell membrane thickness -> ion channels/pors, carrier proteins, and enzymes

Peripheral: on just the surface of the membrane either on the internal or external surface - act has hormone receptors
A-218. What are the differences between Tight and Gap junctions (intercellular connections)?
Tight: sometimes acts as pathway for solute movement b/t cells

Gap: always allow passage of current and/or ions from one cell to the other
A-218. What are the two types of simple diffusion?
1.) Those moving down a gradient from high to low [ ] (water)

2.) Moving down concentration gradient through a channel in the membrane (e.g. voltage gated and chemical (ligand) gated channels) - Na in action potential and ACh binding to channel to allow for Na movement
A-218. Does facilitated transort require ATP? Waht does it require?
No. Carrier protein
A-218. What are the two types of active transport?
Primary and Secondar

Primary: direct movement of ion w/ help of ATP or counter movement of different ion in the pump

Secondary: movement of ion due to primary transport either in the same or opposite direction as the ion from the primary transport.
A-218. What are the roles of K and Na channels with regards to action potentials?
K: maintains resting membrance potential

Na: closed at rest, open to depolarize the cell and propagate the action potential
A-218. What are the different types of neuronal fibers, example of, and conductivity?
A-alpha: a-motorneuron, fast

A-beta: touch, medium

A-delta: pain afferents, medium

A-gamma: g-motoneuron to muscle spindles, medium

B: pre-gang fibers of ANS, medium

C: post-gang fibers of ANS, slow
A-218. What is the difference between inhibitory and excititory NTs?
Inhibitory: hyperpolarize PSM (Na & K channels)

Excitatory: depolarize PSM (Cl- channels)
A-218. D1_____adenylate cyclase (AC) and D2_______AC. What does this lead to?
D1: activates, inc Ca in the terminal bulb

D2: inhibit, dec Ca into terminal bulb
A-218. How do GABA-a and GABA-b receptors work?
A: increase Cl- conduct. target of benzos and barbituates

B: increase K permiability

Both inhibit signal transduction
A-218. This is the pnly gland that secretes epinephrine.
Adrenal gland
A-218. What NT is released in all ANS preganglionic nerve fibers and in the PNS postganglionic nerve fibers?
Acetylcholine
A-218. What are the two types of cholinergic receptors and their locations?
Muscarininc: on all parasympathetically innervated tissues

Nicotinic:
-type I: ALL postganglionic neurons in PNS SNS
A-218. Where can you find alpha II receptors?
Beta Islet cells in pancreas

Platelets

Presynap. nerve bulbs in SNS and CNS
A-218. What are the dominant receptor types on in the viscera withregards to SNS/PNS?
SNS: alpha 1 except, in the heart, liver, gallbladder, and bronchi (B2)

PNS: M3 receptors on everything except the heart (M1)
A-218. Stimulation of what receptor causes coagulation?
Alpha 2
A-218. How does the Hall Pike Bithermal Caloric Test asses labyrinth health?
COWS

Cold water Opposite nystagmus

Warm water same side nystagmus

No response = dead labyrinth