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19 Cards in this Set
- Front
- Back
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What is the MOA of probenecid?
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blocks tubular secretion o fpenicillin
blocks tubular reabsorption of uric acid |
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What drug is used to treat hypertensive crisis in the hospital setting?
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sodium nitroprusside
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ACEIs are contraindicated in what population?
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pregnant pts
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What is the MOA of bromocriptine?
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inhibits prolactin release
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Which diuretic would be used to treat hypercalcemia?
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loop diuretics: furosemide, ethacrynic acid
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What anti-anginal drug can be used as an antidote to toxic cyanide?
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nitroglycerin b/c it generate metHb (Fe3+) which binds cyanide
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What is the MOA of dypyridamloe?
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PDE inhibitor
increase cAMP --> inhibits degrnaulation of platelets to decrease aggregation |
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What is used to monitor warfarin therapy?
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Pt or INR: extrinsic pathway
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What is the main SE of quinidine?
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potentiates digitoxin toxicity
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Which inotropic drug enhances renal blood flow and is particularly useful for tx of shock?
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dopamine
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What is the MOA of theophylline?
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PDE inhibitor
increases cAMP |
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What is specificity?
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the probability that a healthy person will have a negative test D/ (B+D)
confirms dx |
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What is PPV?
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probability that a positive test results indicates sickness A/(A+B)
higher in pops with high prevalence |
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What is NPV?
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probabilty that a negative test results indicates a healthy person D/ (C+D)
higher in pops with low prevalence |
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What is incidence?
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number of NEW ppl that develop a dz in one year per 100,000 population
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What is a type I error?
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null hypothesis is REJECTED although it is TRUE
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What is the P value?
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probability of type I error (null hypothesis is REJECTED although it is TRUE)
the lower the P value the better |
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What kind of research study would you conduct if you wanted to identify risk factors?
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case control study (retrospective)
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What does a +1 correlation coefficient indicate?
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a perfect correlation
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