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30 Cards in this Set
- Front
- Back
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Which infection of the upper respiratory tract is self-limiting?
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Laryngitis
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Does the genus Streptococcus divide along the flat plane (long chain) or cluster?
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Long chain
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What are the characteristics in cultivation for Streptococcus? (3 things)
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Fastidious
Mesophile Capnophile |
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What are the morphology for Streptococcus? (4_
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1.Chains or pairs
2.Gram-positive 3.Catalase-negative 4.non-motile |
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What is the specific antigenicity characteristic for GAS?
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NAG + rhamnose
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Which Lancfield groups are pathogenic?
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A, B, C, D, F & G
Not E! |
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Is Enterococcus faecalis considered Group D Streptococcus?
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NO!
It's a Lancefield group for Group D but NOT a Strep group for D |
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What is the test that you can use to distinguish Strep. pyogenes from other alpha hemolysis Strep?
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PYR-positive L-pyrrolidonyl arylamidase
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Which class of emm gene is responsible for sequelae of disease?
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Class I, M protein
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Which streptolysin is antigenic? Is this streptolysin responsible for the deep cut hemolysis or just surface colony?
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Streptolysin O (Oxygen labile)
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Which protein is responsible for Scarlett fever?
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Spe A
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Spe A is released by which strain of Streptococcus pyogenes?
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Lysogenized strains
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Which virulence factor is responsible for Streptococcal TSS?
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SpeA
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Which pyogenic inflammation do you NOT see in adult?
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cervical lymphadenopathy
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Why is it important to treat Strep pyogenes infection before day 9 (when it is self-limiting)?
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Because if not doing so, immunologic disease can occur due to Type II hypersensitivity
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What is the most serious sequelae in pharyngitis?
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Acute Rheumatic Fever (ARF)
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If protein M antibodies are made and attacking in the host, subsequent to a Strep infection, where in the body does it like to attack?
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Joints & Heart
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What are the signs or Scarlettina?
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Strawberry Tongue
Pastia Lines (Thomson Sign) Desquamation Punctate, blanching erythematous rash (sandpaper rash) Circumoral pallor |
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Untreated GABHS pharyngitis in developing countries can lead to?
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ARF
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What is the modified Jone's criteria for ARF?
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2 major
(or) 1 major & 2 minor |
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What are the five major of ARF?
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1.pancarditis
2.migratory polyarthritis 3.chorea 4.subcutaneous nodules 5.erythema marginatum |
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What are the four minors of ARF?
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1.Arthralgia
2.elevated ESR or CRP 3.Fever 4.Prolong PR interval |
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Perivascular myocardial granulomas, pathognomonic lesions, are called what?
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Aschoff bodies
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A Type III hypersensitivity, in primarily children, preceded by a cutaneous & pharyngeal infection of S. pyogenes may lead to what type of sequelae?
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Acute Poststreptococcal Glomerulonephritis
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What are some of the symptoms of acute poststreptococcal glomerulonephritis in children
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Puffy face
Hematuria Hypervolemia |
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What test can a physician use in his office to screen for S. pyogenes? (very highly sensitive, no false negatives)
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RADT
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What is RADT?
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a rapid antigen detection test used to test for A antigen form of C carbohydrate
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What is S. pyogene sensitive to? (antibacterial drug)
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Bacitracin
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S. pyogene is called GAS, Group A Strep, because it is A is for alpha hemolysis ability? T/F
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False
A is for Group A, which include alpha, beta, and gamma hemolytic bacteria |
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What drug is most effective in prophalaxis of S. pyogene infection?
If the DOC doesn't work, what is next? If a population is resistant to macrolide in the treatment of S. pyogene, what do you use next? |
DOC: Penicillin
if resistant to beta-lactam, use 1.cephalosporins, or 2.macrolides (Azithromyacin, Clarithromycin, or Erythromycin) if macrolide resistant, use clindamycin |
