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25 Cards in this Set
- Front
- Back
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question
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answer
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T cell that activates macrophages, virus and intercellular bacteria
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TH1
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T cells that secrete cytokines to activate B cells to make antibodies
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TH2
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T cells that secrete cytokines to promote neutrophil-mediated inflammation
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TH17
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Suppres T cells
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Treg
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Antibody most abundant over mucosal surfaces, breast milk
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IgA
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Antibody important to opsonization, CTL (Cytotoxic T lymphocytes) and feedback inhibition of B cells (1-4)
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IgG
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Antibody that mediates mast cell degranulation
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IgE
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Induce antiviral state and increase expression of class I MHC to signal T cells, block viral replication
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IFNa,b
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Major cytokine that activates macrophages to kill ingested microbes
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IFNg
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Pro-inflammatory, induce fever, acute phase
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TNF
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Cytokine that inhibits T cell activation and differentiation of Treg
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TGFb
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Interleukin responsible for the production of inflammation, as well as the promotion of fever and sepsis
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IL-1
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Induce proliferation of antigen activated T cells after activation, T cell growth factor
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IL-2
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Drives TH2 development and induces switch to IgE
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IL-4
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Cytokine that activates eosinophils
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IL-5
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Induces proliferation of plamsa cells, Pro-inflammatory, acute phase response
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IL-6
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What cytokines are needed for memory T cells to survive ?
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IL-7
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Cytokine that down-regulates immune responses
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IL-10
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Induce TH1 development
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IL-12
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TH2-derived cytokines that stimulate production of IgE
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IL-13
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What cytokines are needed for memory T cells to survive ?
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IL-15
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cytokines to promote neutrophil-mediated inflammation
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IL-17
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From T cells to B that facilitate antibody production
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IL-21
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cytokines to promote neutrophil-mediated inflammation
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IL-22
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