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27 Cards in this Set
- Front
- Back
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What medications are used for migraine prophylaxis?
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***PAMDVT - Bo
Propranolol Amitriptyline Methylsergide Divalproex Verapamil Topiramate BOTOX |
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MoA of Triptans? Caution if used with?
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5HT receptor agonists
Caution: CAD uncontrolled HTN Pregnancy |
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Triptans are contraindicated with?
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Ergots
MAOI's Linezolid (Zyvox) |
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Px counseling for Triptans?
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Don't exceed the max dose.
Notify MD immediately if experiencing chest pain, shortness of breath, heart throbbing or skin reactions. Avoid SUN EXPOSURE. |
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What is Treximet? Frequency of dosing?
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Sumatriptan 85mg + Naproxen 500mg
Dose: may repeat in 2H |
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What is the frequency of dosing for Triptans?
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Everything can be given Q2H except for Amerge (Naratriptan)
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What is Amerge? Max dose?
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Amerge (Naratriptan)
Max: 5mg/QDay |
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Brands for Rizatriptan? Max dose?
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Rizatriptan (Maxalt, Maxalt MLT)
Max: 30mg/QDay |
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Brands for Sumatriptan? Max dose?
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PO Imitrex: 200mg/QDay
SC (cluster HA) Imitrex: 12mg/mL, max of 2x QDay SC (Sumavel Dosepro): 12mg QDay max NS: 40mg QDay max |
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What is Zomig? Forms? Max dose? Dose in hepatic disease?
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Zomig (Zolmitriptan) comes in tabs and ODT (ZMT)
Max: 10mg QDay In hepatic disease use the lower dose, <2.5mg; break 2.5mg tab in 1/2 |
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What is Axert? Max dose?
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Axert (Almotriptan)
Max: 25mg QDay |
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What is Frova? Max dose? Is this better than the other triptans?
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Frova (Frovatriptan)
Max: 7.5mg QDay LONGEST HALF LIFE |
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What is Relpax? Max dose? How does it differ from the other triptans?
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Relpax (Elatriptan)
Max: 80mg QDay CYP3A4 SUBSTRATE!!!! |
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List the different Triptans
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***No Man Saw Zorro Act Fast Enough
Naratriptan (Amerge) Maxalt (Rizatriptan) Sumatriptan (Imitrex) Zolmitriptan (Zomig) Almotriptan (Axert) Frovatriptan (Frova Elatriptan (Relpax) |
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What forms does Dihydroergotamine mesylate come in?
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Migranal - Nasal Spray (only for migraine HA)
DHE 45 - IM injection |
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What is Ergotamine tartrate?
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Ergomar - SL tabs
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What is Cafergot?
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Ergotamine + caffeine (tabs & suppositories)
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What are the cautions/contraindications for using Ergots?
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***CCHHRaP
Category X CAD Hypertension Hepatic Renal Peripheral Vascular Disease |
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Give 2 groups of drugs with major drug interactions if used with Ergots
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Beta Blockers: contraindicated
Inhibitors: increase ergots (3A4) |
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What is the dosing for Migranal?
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0.5mg (1 spray) in each nostril, may repeat in 15 minutes
Max: 3mg |
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What is the dosing for DHE 45?
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1mg IM: may repeat 2x's at 1H intervals
Max: 3mg/day & 6mg/7 days |
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Patient counseling when using Ergots.
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Don't exceed recommended dose.
Contact MD if you experience: - Irregular heart beat - N/V - numbness or tingling of toes or fingers - pain or weakness of the extremities |
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Dosing for Ergomar?
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Ergomar (ergotamine tartrate)
Dose: 2mg SL Q30 min Max: 6mg/day or 10mg/7 days |
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What are the forms for Cafergot? Dosing?
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Tabs: 1mg ergotamine/100mg caffeine Q30 min
Max: 6 tabs/attack or 10 tabs/wk Suppositories: 2mg ergotamine/100mg caffeine Max: 2/attack or 5 supp/wk |
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What is Sansert? Indications? Dose?
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Sansert (methylsergide), is used for prophylaxis
Start: 2mg PO QD and titrate to 4-8mg/day with meals |
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Patient counseling points for Sansert?
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Take with FOOD or MILK.
MONITOR CALORIC INTAKE to avoid weight gain. DROWSINESS/DIZZINESS, use caution when driving DRUG FREE PERIOD every 3-4 weeks to avoid FIBROTIC THICKENING OF THE HEART. Don't stop abruptly. Contact MD if you experience cold, numb, or painful extremities. |
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What is an OTC medication for Migraine?
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Excedrin Migraine (Acetaminophen + Aspirin + caffeine)
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