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12 Cards in this Set
- Front
- Back
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Major endogenous agonist for adrenergic receptors.
- Name 2 |
Norepinephrine
Epinephrine |
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Major endogenous agonist for adrenergic receptors.
- What TYPE of compound are these? |
Catecholamines
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Major endogenous agonist for adrenergic receptors.
- What are the two components of its structure? |
Catechol
Amine moeity |
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Adrenergic receptor agonist activate what kind of receptor?
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Adrenoreceptor
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Adrenoceptor are found where?
List 4 |
Smooth muscle
Exocrine gland Cardiac muscle CNS |
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List the three adrenoreceptors.
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Alpha 1 adrenoreceptor
Alpha 2 adrenoreceptor Beta adrenoreceptor |
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List all the subtypes of:
- alpha 1 adrenoreceptors |
alpha (1A) AR
alpha (1B) AR alpha (1D) AR |
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List all the subtypes of:
- alpha 2 adrenoreceptors |
alpha (2A) AR
alpha (2B) AR alpha (2C) AR |
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List all the subtypes of:
- beta adrenoreceptors. |
Beta 1
Beta 2 Beta 3 |
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What kind of ligand inhibits adenylyl cyclase?
How? |
Alpha 2 adrenoreceptor ligand
Causes dissociation of the inhibitory G protein (Gi) into its subunits |
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Coactivation of more than one receptor subtype for EPI can result in secondary-messenger responses, which are?
List 3 |
Opposing, Additive, Independent
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Which adrenoreceptor ligand binds to Gs?
This leads to? |
alpha 1 receptor ligand
increased intracellular Ca2+ |
