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9 Cards in this Set
- Front
- Back
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What are some risk factors for prostate cancer?
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> 50 yrs, AA > whites, genetics, family history, inflammation, lifestyles, vasectomy > 20 yrs ago
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Prevention of prostate cancer?
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finesterie; dutasteride; vit E; beta carotene are trials
NO CHEMOPREVENTION RECOMMENDATIONS |
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What screening should be done for prostate cancer?
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DRE - digital rectal exam
PSA - prostate specific antigen |
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What are the levels for PSA?
what about free PSA levels? what will finesteride do to levels? |
normal 0-4ng/mL
biopsy needed 2.5-4ng/mL highly suspect of malignancy >10ng/mL free PSA < 25% associated with prostate cancer finesteride will reduce PSA level by 50% so double lab values baseline PSA > 0.6 begin annual screening baseline PSA < 0.6 recheck in 5 yrs |
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What are the Gleason score values?
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2-4 = slow growing well differentiated
8-10 = poorly differentiated |
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what are the risk levels?
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LOW - A - gleason < 6, PSA < 10
intermediate - B - gleason 7, PSA 10-20 high - C - gleason 8-10, PSA > 20 very high - D - any metastasis |
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DRAW the low risk and intermediate treatment algorithms.
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see notes 35
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What should monitoring after the treatment contain?
what about for pts who recieve surgical ADT? |
serum PSA q 6-12 months for first 5 yrs
if PSA doubles in 3 yrs start new therapy consider baseline bone mineral density study |
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How do you treat androgen independent prostate cancer?
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chemotherapy
clinical trials prefered taxane based |
