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30 Cards in this Set
- Front
- Back
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Chlam gen
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Chlam gen:
- spherical, minute intracellular - LPS but no peptidoglycan - G stain no good, use mod Ziehl- Neelsen, Giemsa, methylene blue |
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Chlam dx
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Chlam dx:
- FAT, Ag capture ELISA - serology: Ab detection - not culturable in regular media: use chick embryos, tissue culture, PCR detection |
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Chlam pathogenesis
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Chlam pathogenesis:
- most inapparent, persistent inf 1. infective stage: elementary bodies bind to host cell receptors 2. entry 3. inclusion body: reticulate bodies in cell vacuole 4. division into numerous elementary bodies 5. cell lysis 6. infection of other cells 7. host cytokines 8. local tissue damage |
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Chlamidophilia psittaci dz
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Chlamidophila psittaci dz:
- subclinical in wild, dom birds - inf by inhalation or ingestion - predisp by stress 1. generalized inf, loss of cond 2. resp distress: pneumonia, airsacculitis 3. diarrhea 4. conjunctivitis, nasal disc - PM: hepatosplenomegaly, airsacculitis, peritonitis |
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Chlamidophilia psittaci dx
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Chlamidophilia psittaci dx;
1. smear : modified Ziehl Neelsen, acid fast, Giemsa 2. Ag capture or Ab ELISA 3. Immunohistochemistry 4. FAT 5. PCR |
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Chlamidophilia psittaci tx
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Chlamidophilia psittaci tx:
- TETRA - imported birds: quarantine, prophy tetra in feed - proper husbandry, transportation - prevent zoonotic hazard via aerosol inhalation |
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Chlamidophilia psittaci humans
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Chlamidophilia psittaci humans:
- secondary hosts - Psittacosis: respiratory - abortion |
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Chlamidophilia felis
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Chlamidophilia felis:
- endemic: dom cats worldwide - maternal Ab protect until 7-9 weeks - acute/ chronic/ recurrent conjunctivitis, rhinitis - rarely pneumonia - zoonotic: flu, chronic cough - vaccs: dec severity - TETRA |
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Chlamidophilia abortus
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Chlamidophilia abortus:
- R, pigs - abortion: US, Europe |
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Chlamydophilia pecorum
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Chlamidophilia pecorum:
- cattle - sporadic encephalomyelitis in USA |
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Chlamydiphilia pneumoniae
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Chlamydiphilia pneumoniae:
- horse, koala, humans - mild respiratory infection |
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Chlamydia trachomatis
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Chlamydia trachomatis:
- humans only - eye inf, urethritis |
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Ehrlichia canis dz
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Ehrlichia canis dz: worldwide
- canine MONOCYTIC ehrlichiosis 1. tick bite 2. blood invasion 3. monocyte, lymphocyte inf 4. lnn, spleen, liver, lung, nasal mucosa 5. hemorrhage |
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Ehrlichia ewingii
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Ehrlichia ewingii:
- hosts: dogs, ticks - canine GRANULOCYTIC ehrlichiosis - buffy smear: mod Giemsa, morulae in PMNs |
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Rickettsia ricketsii dz
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Rickettsia ricketsii dz:
- hosts: dogs, ticks, humans - rocky mountain spotted fever - Americas, S Can - humans: Black measles, fever, headache, rash |
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Neorickettsia helminthoeca dz
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Neorickettsia helminthoeca:
- hosts: dogs, fish w/ flukes - salmon poisoning dz: fever, vomiting, bloody diarrhea, death >50% cases - fluke Nanophyteus salmincola infected with pathogen: inf mononuclear cells - intestine --> blood --> spleen, liver, lung, brain - Western US |
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Anaplasma phagocytophilum
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Anaplasma phagocytophilum:
- hosts: horses, ticks, dogs - equine ehrlichiosis: acute, jaundice, fever, limb edema, petechiae - inclusion bodies/ granulocytic morulae in PMNs - USA, CAN - oxytetracycline: rec in 3 weeks |
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Neorickettsia risticii (Ehrlichia risticii)
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Neorickettsia risticii (Ehrlichia risticii):
- hosts: horses, snails/ insects harboring infected trematode - potomac horse fever: colitis, diarrhea, leukopenia, fever, abortion, infected Macs ~ 30% fatal - NA, Europe, US: low areas near water - use FAT, then oxytetracycline - commercial bacterins = partial protection |
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Coxiella burnetti
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Coxiella burnetti:
- hosts: N. America= R, humans, ticks - Q fever subclin, abortion small R, fluids infective - humans: flu - Ziehl-Neelsen stain: red/ pink - vaccs: humans, animals - tetra |
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Ehrlichia ruminantium
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Ehrlichia ruminantium:
- hosts: R, ticks, spread by cattle egret - heartwater: hydropericardium, hydrothorax - convulsions, death - Africa, Carib, Guadloupe, Antigua |
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Anaplasma marginale
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Anaplasma marginale:
- cycle in cattle , ticks - RBCs infected, typically PM enlarged spleen - sporadic: S USA |
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Obligate intracellular small bacti
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Obligate intracellular small bacti:
- G-, minute - stain: Giemsa, mod Ziehl- Neelson, FA 1. Chlam 2. Ehrlichia 3. 'rickettsia 4. Coxiella 5. Cowdria |
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Ehrlichia canis signs
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Ehrlichia canis signs:
1. epistaxis 2. fever 3. dyspnea 4. lymphadenopathy 5. oculonasal discharge 6. peripheral edema: vasculitis 7. infected lymphocytes, neutrophil inclusion of Ehrlichia |
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Ehrlichia canis dx
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Ehrlichia canis dx:
1. smear w/ Giemsa 2. intracellular inclusions in buffy 3. thrombocytopenia 4. serology: FA, ELISA 5. cell culture isolation 6. PCR |
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Ehrlichia canis tx
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Ehrlichia canis tx:
- doxy, Tetra - blood tranfusion - tick control |
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Rocky Mtn SF signs
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Rocky Mtn SF signs:
1. hyperemia 2. edema, necrosis of extremeties 3. petechiae of mucous mem 4. fever 5. necrotizing vasculitis |
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Rocky Mtn SF dx, tx
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Rocky Mtn SF dx, tx:
- serology - NO vaccs - w/i 5 days of onset: doxy - oxytetra, tetra - zoonotic: wear gloves while removing ticks |
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Salmon poisoning dx, tx
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Salmon poisoning:
1. dx: fluke eggs in feces - history: raw fish in endemic areas - clin signs, rickettsial bodies in cells 2. tx: tetras, chloramph |
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Canine anaplasmosis
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Canine anaplasmosis:
- Minn, Wisc - subclin or chronic - mostly > 8 y/o - polyarthritis like Lyme - morulae in PMNs: blood, jt fluid - FA test, doxy |
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Bartonella hensilae
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Bartonella hensilae:
- cat scratch fever - 20% US cats carry - culture, PCR: Ab testing not reliable so culture 3x (sporadic) - enro, doxy |
