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5 Cards in this Set

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Toxicokinetics

The study of how a toxic substance gets into the body and what happens to it while in the body

Toxicokinetic phase

Exposure --> Toxicokinetics --> Toxicodynamics


Includes: absorption, distribution, metabolism and elimination

Primary Routes of Exposure (3)

1) Gastrointestinal tract


2) Resipiratory tract


3) Skin

Absorption

Entry of toxicants to the body.


Must pass cellular barrier and enter the bloodstream to be considered "absorbed"

Factors Affecting Absorption (3)

1) route of exposure


2) concentration of substance at the site of contact


3) chemical and physical properties of the substance