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5 Cards in this Set
- Front
- Back
Toxicokinetics |
The study of how a toxic substance gets into the body and what happens to it while in the body |
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Toxicokinetic phase |
Exposure --> Toxicokinetics --> Toxicodynamics Includes: absorption, distribution, metabolism and elimination |
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Primary Routes of Exposure (3) |
1) Gastrointestinal tract 2) Resipiratory tract 3) Skin |
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Absorption |
Entry of toxicants to the body. Must pass cellular barrier and enter the bloodstream to be considered "absorbed" |
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Factors Affecting Absorption (3) |
1) route of exposure 2) concentration of substance at the site of contact 3) chemical and physical properties of the substance |