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27 Cards in this Set
- Front
- Back
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Cause of hemotogenous osteomyelitis in neonates.
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Group B Strep
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Cause of hemotogenous osteomyelitis in children.
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GAS, H. Flu
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Area of spine most commonly affected in adult hemotogenous osteomyelitis.
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Lumbar, Thoracic
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Hematogenous osteomyelitis in children most commonly begins in __________ because ___________
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metaphysis of long bones bc highly vascularized
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Osteomyelitis secondary to prosthesis is most commonly caused by ________.
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Coag negative staph
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10% of honey contains this bacteria.
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Clostridium botulinum
BAD UNTIL 2 years old |
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List 4 organisms that produce a single A:B toxin.
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Botulism
Tetanus Cholera Diphtheriae |
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This gram positive rod does not produce spores.
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Corynebacterium diphthariae
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The toxin of this organism inhibits host cell protein synthesis.
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Corynebacterium diphthariae
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This organism produces an A:5b toxin.
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Cholerae (vibrio)
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Clinical presentation of Osler's Nodes.
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TENDER ulcerations on palms/soles
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Clinical presentation of Janeway Lesions.
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NONTENDER ulcerations on palms/soles
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General treatment recommendation for endocarditis.
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IV CIDAL Abx x4-6 weeks
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Immunity induced by inactivated vaccines.
Subtypes (3). |
HUMORAL ONLY
Whole Inact'd (virus, bacteria) Fractional (protein, subunit, TOXOID) Polysaccharide Based (pure, conjugate) |
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Inflammation of bone and marrow is due to ________ (2)
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Pyogenic and mycobacteria
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Disease in sight of eradication in 2011.
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Polio
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Tetanus vaccine given alone with _______ (2)
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Diphtheria
Pertussis |
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Hemotogenous osteomyelitis is caused by ______________
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Staph aureus OR E coli
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Joint infections: causes in younger patients vs older patients
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Younger: neisseria gonorrhea
Older: staph aureus |
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Osteomyelitis with vascular insufficiency:
Mono or Polymicrobial Cause |
POLY
Due to: staph and strep staph/strep with gram neg Anaerobes |
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Most osteomyelitis occurs through _________.
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Hematogenous route
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Clostridium botulinum:
Gram Stain Shape |
GRAM POZ ROD
SPORES!!!! |
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Clostridium perfringens:
Method of infection |
WOUND INFECTION
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Clostridium diphtheriae:
Toxin effects |
NO SPORES
Toxin inhibits protein synthesis and leads to pseudomembranous formation on throat |
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Clostridium species with 12 exotoxins.
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C. perfringens
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This bacterium releases alpha-toxin, a lecithinase that lyses cells.
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C. perfringens
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This bacterium releases Toxin A and Toxin B. Effects?
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C. difficile
Toxin A: enterotoxin (watery diarrhea) Toxin B: Cytotoxin (pseudomembranous colitis) |
