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25 Cards in this Set

  • Front
  • Back
Primary Motor Cortex:
Input/output
Signs of Dysfunction
Input: VL thal, primary somatosensory
Output: Internal capsule

Dysfn: flacid hemiparesis/hemiplegia on contralateral side followed by spasticity
Spatial vs Object Alteration: related to which region of brain?
Spatial: animal stuck on first rewarded side, won't look on other side (perseverate)

Object:snack under cylinger/rectangle, will only look under cylinder

Prefrontal Lesions-->difficulty alternating
Premotor Cortex:
Input/output
Signs of Dysfunction
Input: VA thal, secondary somatosensory
Output: Motor cortex and contralateral premotor area (via CC)

Signs of Dysfn: Apraxia, contralateral fine motor deficits, difficulty using sensory feedback
Functions of premotor cortex
Integration of sensory and motor information

Praxis (learned motor movements--stamping, addressing, mailing an envelope)
Functions of frontal eye field.
Volitional eye movement in contralateral visual field (NOT PASSIVE EYE MOVEMENT)

Active visual search (can follow finger with eye, but can't look to left on command)
Frontal eye field:
Signs of dysfunction
Failure to move eyes volitionally to contralateral visual field
Intact passive eye movement
Poor visual search
Dorsolateral Cortex:
Function
Signs of Dysfunction
Integration of multimodal sensory info
Generation of multiple response alternatives
Selection of appropriate response
Spatial working memory
Maintenance of set, persistence
Set shifting, flexibility

Dysfn:
Trouble integrating sensory info
Generation of few, stereotyped response alternatives
Poor judgment in response selection
Impersistence
Perseveration
Patient is asked to draw as many different objects as possible. Ends up drawing objects similar to each other.

Area of dysfunction?
Dorsolateral Cortex

(Figural Fluency)
Describe the Figural Fluency Test
Draw as many diff objects as you can

(Dorsolateral Cortex)
A patient has difficulty completing a pattern of x's and o's.

Area of dysfunction?
Dorsolateral Cortex

Luria's test
Describe Luria's Test
Continue pattern of x's and o's or plateaus and peaks

Dorsolateral Cortex
What is executive function? Associated brain region?
Executive process = ability to utilize sensory input from multiple modalities (visual, auditory) in generation of appropriate responses

Dorsolateral Prefrontal Cortex
A patient begins drawing the face of a clock and numbers it from 1-22.

Dysfunction of what brain area?
Dorsolateral prefrontal cortex

(poor executive ability)
A patient is unable to identify pictures of different parts of a key as a key.

Dysfunction of what brain area?
Dorsolateral prefc

Poor executive ability
A patient is given an image to copy and later draw from memory. He performs poorly on both.

Area of dysfunction?
Frontal lobes: poor organization of learning/recall
Orbitofrontal Cortex:
Input/output
Signs of Dysfunction
Orbitofrontal
Input: limbic/olfactory, ventral visual
Output: autonomic musculature, endocrine system (cholinergic, caudate, autonomic system)

Signs of Dysfn:
Disinhibition, socially inappropriate behavior
Failure on feature working memory tasks
ANOSMIA (can't recognize smells)
Confabulation
Go-No Go tasks test what?
Orbitofrontal cortex
A patient is instructed to draw a cross and instead draws an ambulance.

Area of dysfunction?
Orbitofrontal cortex (intrusion and disinhibition)
Cingulate/SMA:
Functions
Signs of dysfunction
Cingulate/SMA
Fn: drive, motivation, environmental exploration, complex attention

Dysfn:
Apathi, akinetic mutism, ALIEN HAND SYNDROME, complex attentional deficits, delayed habituation
Small subcortical lesions can mimic ______________________
large cortical lesions

(parallel but separate connections to caudate and thalamus)
Give examples of frontal release signs. What are they indicative of?
Frontal release signs: snout, suck, glabellar, grasp

Indicative of frontal lobe damage

as as Gegenhalten (patient resists movement, can't inhibit autonomic stretch reflexes) and Cogwheeling
Frontal or magnetic gaits also indicative of frontal injury
Psychiatric effects of frontal dysfunction?
Shziophrenia
Delusions
Depression
OCD

Frontotemporal Dementia...
Symptoms of Korsakoff's Syndrome
Dysinhibited behavior, aboulia (lack of will/motivation)--no concern for environment
A patient begins copying x's and o's correctly, but then begins calling you hot stuff.

Diagnosis?
Korsakoff's Syndrome: intrusions and disinhibition
FTD vs AD
FTD: early changes in behavior and personality, deficits in executive and inhibitory fns, anterior atrophy

AD:
Preservation of personality and social bhvr
Deficits in naming and construction, frank amnesia after delay
Generalized and hippocampal atrophy