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27 Cards in this Set

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What is an agonist of the biceps? Antagonist?
Agonist: Brachialis
Antagonist: Triceps

(both allow for flexion/extension and joint stabilization via co-contraction)
Fast Muscle vs Slow Muscle
-Color
-Speed of Tension Rise
-Speed of Tension Decay
-Fatigability
-Energy Source
-Mitchondria Count
-Vascularization
Fast:
White
Fast rise in tension
Fast decay in tension
Rapid fatigue
Glycolysis (anaerobic)
Sparse mitochondria
Poor capillary supply

Slow Muscle:
Red
Slow rise in tension
Slow decay in tension
Slow fatigue
Oxidative metabolism
Plentiful mitochondria
Rich capillary supply
Soleus: muscle type
strong, slow
Gastrocnimeus: muscle type
Fast, fatigue-resistant (intermediate--some mitoch, some ATPase)
Extraocular muscles: muscle type
Fast, fatigable
Where are alpha-MN cell bodies located?
Ventral horn of SC
Motor Unit vs Motor Neuron Pool
Motor Unit: 1 alpha-motor neuron + all mm fibers it innervates

Motor Neuron Pool: all alpha-MN's that innervate the same muscle
What is the relationship of motor unit size and muscle control?
The smaller the motor unit size (smaller ratio of alpha-MN's to muscle fibers) the more fine tuned control you'll have
What determines a muscle fiber's slow/fast properties?
The alpha-MN innervating it (determines twitch props, number of mitcoh, etc)
How do motor neurons dictate muscle force?
1) Firing rate of active MN's (1AP-->twitch; 2AP-->Temporal Summation; Multiple AP-->Tetany)
2) Recruit more active MN's in pool
What are fibrillations? When are they visible?
Fibrillations are muscle contractions that are only visible on EMG; they're abrnoraml and usually result of denervation
What are fasciulations? When are they visible?
Visible abnormal contractions

Can be seen in those with Polio
What types of neurons converge onto alpha-motor neurons in the spine?
1) Sensory inputs (Ia, II axons) from muscle spindles
2) Same/nearby segments via spinal IN's
3) Propriospinal input
4) Supraspinal control from BS and brain
What are the afferent innervations of muscle?
Muscle spindles (stretch receptors): sense length of m (Ia axons)

Golgi Tendon organs: sense force generated by m (Ib axons); sensitive to length
Extrafusal vs Intrafusal fibers
Extrafusal: innervated by alpha-MN; generate power

Intrafusal: innerv by gamma-MNs (not for contraction; for determining stretch)
Function of golgi tendon organs.
Measure tension of muscle via
List two ways stretch receptors can be activated.
1) Contract muscle
2) Contract intrafusal fibers of stretch receptor (no contraction necessary)
What types of neurons fire in response to muscle stretching?
Gamma motor neurons
Describe alpha-gamma co-activation.
When muscles contract (via alpha MN's), Stretch receptors slacken, goes offline.

BUT co-contraction of stretch receptors via gamma neurons keep stretch receptors taught and online

Thus muscles are always sensitive to stretch
Provide an example of a monosynaptic and polysynaptic reflex.
Monosynaptic: stretch reflex (myotatic, knee-jerk, tendon-jerk)

Polysynaptic: withdrawal reflex
Stretch Reflex Circuit acts directly on ______________ muscle
homonymous (muscle that's being stretched)
Function of Jendrassik’s maneuver?
Increases briskness of reflex jerk (demonstrates that reflex circuits can be modulated)
How does the Hoffman reflex work?
Shock afferent and efferent muscle nerves, should expect two jerks:
Immediate jerk (M wave) is due to direct activation of efferent fiber
Delated jerk (H wave) due to activation of Ia afferent fiber (tests reflex)
Explain automatic load adjustment.
Ex: pour beer into glass, increased Fg, increased stretch

Thus:
Increase activity (contraction) of agonist (Ia fibers)
Decreased activity (relaxation) of antagonists (IIb fibers)
Explain the use of servo control when muscle contraction doesn't meet expectations.
If m contraction doesn't meet expectations, muscle spindles provide corrective feedback

Causes alpha-gamma MN's to coactivate, fire together, and contract muscle.
Treatment for rigidity. Side effect?
Alternating dorsal risotomy to decrease descending gamma activity
Would lose reflex arc
Describe the events of the withdrawal reflex of the legs.
Nociceptive stimulus
-->IM Horn
-->Ventral Horn
-->Activate flexors and inhibit extensors on affected limb
-->Inhibit flexors and activate extensors on opposite limb
-->Inhibit extensors