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32 Cards in this Set
- Front
- Back
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What is the most common myositis in adults < 50yo?
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Polymyositis (PM)
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What is the most common myositis in children?
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Dermatomyositis (DM)
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What is the most common myositis in adults > 50yo?
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Inclusion Body Myositis (IBM)
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Muscle weakness that is proximal, symmetrical, and effects the upper and lower limbs is associated with which diagnosis?
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PM and DM
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Muscle biopsy that shows endomysial mononuclear infiltration is associated with which diagnosis?
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PM and IBM
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Myositis with T-Cell mediated attack is associated with which diagnosis?
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PM
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Anti-Jo-1 is associated with which diagnosis?
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PM, DM, Interstitial Lung Disease, Mechanic's Hands
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Anti-SRP is associated with which diagnosis?
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PM
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Anti-PM-Scl is associated with which diagnosis?
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PM, DM, Systemic Sclerosis
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Which myositis has no skin involvement?
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PM
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Which myositis has skin involvement?
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DM
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Muscle biopsy that shows perimysial mononuclear infiltration is associated with which diagnosis?
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DM
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Anti-Mi-2 is associated with which diagnosis?
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DM
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Anti-p155/140 is associated with which diagnosis?
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DM + Malignancy
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DM + Malignancy is associated with which antibody?
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Anti-p155/140
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Gottron's Papules are associated with which diagnosis?
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DM
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Purple, scaly papules on the finger joints are associated with which diagnosis?
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Gottron's Papules; DM
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Heliotrope sign is associated with which diagnosis?
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DM
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Purple-red eyelid discoloration is associated with which diagnosis?
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Heliotrope Sign; DM
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"Shawl Sign" or "V Sign" erythematous rash is associated with which diagnosis?
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DM
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Dilated nail fold capillary loops are associated with which diagnosis?
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DM and LSSc
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Mechanic's Hands are associated with which diagnosis? Which antibody?
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DM; Anti-Jo-1
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Roughening and cracking of the tips and sides of the fingers are associated with diagnosis? With antibody?
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Mechanic's Hands; DM; Anti-Jo-1
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Poikiloderma is associated with which diagnosis?
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DM
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Muscle weakness that is distal (forearm flexors and quadriceps) is associated with which diagnosis?
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IBM
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Muscle biopsy that shows rimmed vacuoles is associated with which diagnosis?
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IBM
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Muscle biopsy that shows basophilic granules is associated with which diagnosis?
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IBM
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Which enzyme finding is associated with PM and DM?
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ELEVATED CREATINE KINASE
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What is the electromyography findings associated with PM and DM?
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Myopathic Potential (low amplitude, short duration, polyphasic) + Normal nerve conduction
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What is a common cause of drug-induced myopathy?
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Statins (antibody to HMG-CoA Reductase)
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What are the 5 poor prognostic factors for PM and DM?
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1. Older Age
2. Cardiac Involvement 3. PULMONARY INVOLVEMENT 4. DYSPHAGIA 5. Malignancy |
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What is the treatment for PM and DM?
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High-dose oral corticosteroids
(IV methylprednisolone if severe or risk factors) Methotrexate, azathioprine IV Ig |
