194-Exam3-Ch33-Drugs Affecting Hematopoiesis

Front 1

Epoetin Alfa

1) treats
2) C/I
3) adverse
4) nurse
5) teach pt
6) drug int

Back 1

1) Anemia in chronic kidney disease(CKD), HIV, cancer and pre-op.
2) Uncontrolled hypertension.
3)Thrombotic effects in CKD. Hypertension in CKD, fever.
4) Consult w/MD about dose adjustment, verify iron availability. Monitor Hb, don't use high target levels of Hb.
5) Advise pt of the need for follow up blood work and the importance of dietary iron.
6) none known

Front 2

Neupogen (filgrastim)

1) treats
2) C/I
3) adverse
4) nurse
5) teach pt
6) drug int

Back 2

1) Increase neutrophil counts in cancer pts.
2) hypersensitivity to E. coli derived proteins. Don't administer 24 hrs before or after chemo.
3) medullary bone pain.
4) Do not dilute in saline, avoid shaking, don't decrease dose before expected nadir, keep refrigerated.
5) Teach pt how to reduce risk of infection due to decrease WBC count.
6) Lithium. (synergistic effect)

Front 3

oprelvekin

1) treats
2) C/I
3) adverse
4) nurse
5) teach pt
6) drug int

Back 3

1) prevents thromboctytopenia in cancer pts.
2) Don't use with or immediately after chemo.
3) CHF or pulmonary edema from fluid retention; atrial arrythmias. Nausea and vomiting.
4) Don't shake or agitate the vial; begin administering 6 to 24 hrs after chemo; monitor intake and output.
5) Contact prescriber if fluid retention occurs; avoid activities that increase the risk of bleeding.