194-Exam 3-Chapter 36- Drugs That Are Cell Cycle-Specific

Front 1

Name the Drugs that are cell cycle-specific

Back 1

5-FU
Etopiside
Paclitaxel
Hydroxyurea

Front 2

5-FU
1-treats
2-C/I
3-adverse
4-Nurse
5-teach pt

Back 2

1. many cancers
2. malnourished, decr. bone marrow, infection,
3. alopecia, sun, Preg D, bleeding, mouth ulcers
4. assess hematologic & neurologic status. Do not exceed 800mg daily, reduce folates such as leucovorin
5. precautions of chemo drugs.
6- diazepam, Leucovorin = synergystic

Front 3

Paclitaxil
1-treats
2-C/I
3-adverse
4-Nurse
5-teach pt

Back 3

1- ovarian & breast cancer (2nd line therapy)
2.anaphalaxis (1st 15 min),
3. alopeica, joint pain, loss of bone marrow function, no preg, less perception
4. base cbc, ecg, vitals. monitor 1st 15 min, then 1st hour. give in combo w cisplatin then premed w steroids, diphen & water
5. anaphalaxis

Front 4

Etopisisde
1-treats
2-C/I
3-adverse
4-Nurse
5-teach pt
6- synergistic w _____

Back 4

1- testicular tumors, small-cell lung cancer
2. hypersensitive,
3. hyposension,dyspnea, bronchospasm, tach
4. concentration stablility, infuse SLOW, never IV push, monitor CBC &WBC, nadir = 7-10 days
5. metallic taste, use hard candy
6- cisplatin

Front 5

Hydroxyurea
1-treats
2-C/I
3-adverse
4-Nurse
5-teach pt
6- synergistic w ______

Back 5

1- hematologic cancers
2. severe anemia, depres. bone marrow,
3. GI, myelosuppression,
4. monitor blood count, transfusion for anemia, give 1 wk prior to radiation, assess bleeding,
5. sensory & sexual disruption, Anemic not stop therapy. report bleeding, infection.