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22 Cards in this Set
- Front
- Back
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A-189. Briefly describe the transmission of malaria.
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Masquitoe w/ sporozoite -> sporozoite to human blood -> goes to liver and becomes merozoite -> goes to RBCs and lysis them -> cycle repeats w/ gametocytes being made sometimes which are picked back up by masquitoes and made in to sporozoites
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A-189. "Black Water Fever" is caused by what?
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Plasmodium falciparum
Lysis all kinds of RBCs -> ton of hemoglobinurea that look black |
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A-189. This creates alveolar cysts, frothy exudates, and spreads to liver, nodes, spleen and BM of AIDs pts.
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Pneumocystitis jiroveci - tissue protazoa
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A-189. This is a type of fluke (flatworm) found in crab meat that penetrates the intestine and ends up in the lung.
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Paragonimus
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A-189. Pt ate some shitty pork while on vacation in south america. What tapeworn does he most likely have?
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Taenia solium
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A-189. What "fish tapeworm" can cause B12 deficiency?
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Diphyllobothrium latum
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A-189. This is th emost common tape worm in the US and most common in the southwest. No animal carrier.
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Hymenolepsis
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A-189. What roundworm (nematode) is known as the pinworm and dx via the scotch tape test?
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Enterobius vermicularis
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A-189. Your pt is from the southwest US and has Fe-deficiency anemia caused by some round worm. What is it?
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Nector americanus
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A-189. Pt ate some undercooked bear and is in a world of hurt, edema, and cardiac issues. What roundworm did he eat?
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Trichinella spiralis
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A-189. What central american roundworn causes lizard skin and river blindness and who carries it?
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Onchocerca volvulus
Blackfly |
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A-189. This worm literally crawls under your skin...
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Dranunculus medinenis
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A-189. Get this round worm from raw seafood, mainly in the US from sushi...
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Anisakis simplex
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A-201. This combines with ATP to form cAMP, whcih via protein kinase A, activates hormone sensitive lipase.
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Adenylyl cyclase
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A-201. Excess acetyl CoA in the cytoplasm is metabolized into this via acetyl CoA carboxylase.
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Malonyl CoA
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A-201. Why do T1DM pts have such thin bodies?
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Lack of insulin = decreased acetyl CoA carboxylase, which leads to few TGs being produced
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A-201. What two things have to occur metabolically for DKA to occur?
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1.) Excess hormone sensitive lipase from lack of insulin
2.) Increase epi release (e.g. times of stress) |
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A-201. Where does arachodonic acid come from (unsat. fatty acid)?
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Eicosanoid
AA broken down to prostaglandins and leukotrienes (potent bronchoconstriction) |
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A-201. What is the rate limiting step in cholesterol synthesis. What drugs act here?
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HMG-CoA Reductase
Statins |
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A-201. What are the two main glycolipids and there general structure?
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Cerebroside - ceremide + 1 sugar
Ganglioside - ceremide plus 3 sugars |
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A-189. What is the structure of a sphingolipid?
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Ceramide + a phosforlyated head
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A-189. Name the associated clinical feature to the correct sphingolipidoses.
1.) Cherry red macula 2.) Angiokeratomos w/ hrt/kid fail 3.) Severe MR 4.) Progressive paralysis 5.) Erosion of long bones |
1.) Niemann-Pick & Tay-Sachs
2.) Fabry's 3.) Krabbe's 4.) Metachromatic dystrophy 5.) Gaucher's |
